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Bone Grafts: Everything You Need to Know. [PDF]
J Periodontal ResThis review classifies bone grafts (autograft, allograft, xenograft, synthetic) by source and osteogenic/inductive/conductive potential, linking material properties and mechanisms to clinical indications in periodontal and dental regeneration. Key challenges—limited osteoinduction, poor vascularisation, unbalanced resorption, handling difficulties, and
Haugen HJ +5 more
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'Smart' biomaterials and osteoinductivity [PDF]
Nature Reviews Rheumatology, 2011 In their recent paper in Nature Reviews Rheumatology, Boyan and Schwartz discussed the use of synthetic biomaterials in repair strategies of large bone defects (Are calcium phosphate ceramics 'smart' biomaterials?Nat. Rev. Rheumatol. 7, 8–9; 2011).1 This News & Views commentary, which is largely based on our publication in the Proceedings of the ...
Yuan, Huipin +8 more
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Osteoinduction and osteoimmunology: Emerging concepts
Periodontology 2000, 2023 AbstractThe recognition and importance of immune cells during bone regeneration, including around bone biomaterials, has led to the development of an entire field termed “osteoimmunology,” which focuses on the connection and interplay between the skeletal system and immune cells.
Richard J. Miron +3 more
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Biology, 2023 (1) Background: Biphasic bioceramics are synthetic bone substitutes that provide greater safety and better predictability in guided bone regeneration.
Paula Buzo Frigério +5 more
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Interferon Effects on Osteoinduction
Connective Tissue Research, 1989 Xenografts of human osteosarcoma growing in athymic mice are inhibited in growth rate by human interferon-alpha (IFN-alpha) treatment. In addition, differentiation of trabecular bone occurs external to the osteosarcomatous tissue and this is entirely dependent on IFN treatment.
Triffitt, J +4 more
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Acta Medica, 2017 Despite the huge research into stem cells and their regenerative properties for bone healing, there are still unanswered questions including the recipient’s respond to the presence of the stem cells, the fate of stem cells inside the bone defect and the ...
Luboš Tuček +4 more
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Osteoinduction by demineralised bone [PDF]
International Orthopaedics, 1998 Bone contains several growth factors, including bone morphogenetic proteins (BMPs), transforming growth factor beta (TGF-beta), insulin-like growth factors I and II (IGF-I and IGF-II), platelet derived growth factor (PDGF) and basic and acidic fibroblast growth factor (bFGF and aFGF).
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Osteoinductive bone graft substitutes [PDF]
European Spine Journal, 2000 This review will summarize the major efforts currently underway to develop osteoinductive bone graft substitutes for minimally invasive spine fusions. The primary categories of substitute include purified bone growth factors, recombinant bone growth factors, and growth factors delivered by gene therapy approaches.
S C, Ludwig, J M, Kowalski, S D, Boden
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Dental Research Journal, 2012 Background: It has been stated that the bone allografts from different tissue banks may lead to various amount of bone induction, so the aim of this study was to evaluate bone regeneration of three demineralized allografts both histologically and ...
Parichehr Behfarnia +3 more
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Вестник трансплантологии и искусственных органов, 2022 Objective: to study the induction of osteogenesis caused by introducing into the defect area broadly porous cryogenically structured 3D carriers, based on serum albumin and loaded with a bioregulator isolated from bovine serum on an experimental model of
A. I. Shaikhaliev +4 more
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