Results 11 to 20 of about 10,653 (208)
Immediate implantation integrates three surgical procedures into one and shortens the treatment cycle, showing great clinical value. However, in patients with periodontitis, the high risk of infection remains a major challenge.
Zhiqiang Qi +10 more
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'Smart' biomaterials and osteoinductivity [PDF]
In their recent paper in Nature Reviews Rheumatology, Boyan and Schwartz discussed the use of synthetic biomaterials in repair strategies of large bone defects (Are calcium phosphate ceramics 'smart' biomaterials?Nat. Rev. Rheumatol. 7, 8–9; 2011).1 This News & Views commentary, which is largely based on our publication in the Proceedings of the ...
Yuan, Huipin +8 more
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Osteoinduction, osteoconduction and osseointegration [PDF]
Osteoinduction is the process by which osteogenesis is induced. It is a phenomenon regularly seen in any type of bone healing process. Osteoinduction implies the recruitment of immature cells and the stimulation of these cells to develop into preosteoblasts.
T, Albrektsson, C, Johansson
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Osteoinductive bone graft substitutes [PDF]
This review will summarize the major efforts currently underway to develop osteoinductive bone graft substitutes for minimally invasive spine fusions. The primary categories of substitute include purified bone growth factors, recombinant bone growth factors, and growth factors delivered by gene therapy approaches.
S C, Ludwig, J M, Kowalski, S D, Boden
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Osteoinduction and osteoimmunology: Emerging concepts
AbstractThe recognition and importance of immune cells during bone regeneration, including around bone biomaterials, has led to the development of an entire field termed “osteoimmunology,” which focuses on the connection and interplay between the skeletal system and immune cells.
Richard J. Miron +3 more
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(1) Background: Biphasic bioceramics are synthetic bone substitutes that provide greater safety and better predictability in guided bone regeneration.
Paula Buzo Frigério +5 more
doaj +1 more source
A clinically relevant model of osteoinduction: a process requiring calcium phosphate and BMP/Wnt signalling [PDF]
In this study, we investigated a clinically relevant model of in vivo ectopic bone formation utilizing human periosteum derived cells (HPDCs) seeded in a Collagraft carrier and explored the mechanisms by which this process is driven.
Eyckmans, Jeroen +3 more
core +1 more source
Stimulation of bone growth with thrombin peptide derivatives [PDF]
Disclosed is a method of stimulating bone growth at a site in a subject in need of osteoinduction. The method comprises the step of administering a therapeutically effective amount of an agonist of the non-proteolytically activated thrombin receptor to ...
Carney, Darrell H. +4 more
core +2 more sources
Interferon Effects on Osteoinduction
Xenografts of human osteosarcoma growing in athymic mice are inhibited in growth rate by human interferon-alpha (IFN-alpha) treatment. In addition, differentiation of trabecular bone occurs external to the osteosarcomatous tissue and this is entirely dependent on IFN treatment.
Triffitt, J +4 more
openaire +2 more sources
Despite the huge research into stem cells and their regenerative properties for bone healing, there are still unanswered questions including the recipient’s respond to the presence of the stem cells, the fate of stem cells inside the bone defect and the ...
Luboš Tuček +4 more
doaj +1 more source

