Results 231 to 240 of about 22,928 (253)
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Skeletal Radiology, 2008
Osteonecrosis of the jaw (ONJ) was first reported in the dental literature in 2003. The term was coined to describe a spectrum of dental problems seen in cancer patients treated with high doses of intravenous bisphosphonates for the prevention of skeletal-related events.
Ian R, Reid, Tim, Cundy
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Osteonecrosis of the jaw (ONJ) was first reported in the dental literature in 2003. The term was coined to describe a spectrum of dental problems seen in cancer patients treated with high doses of intravenous bisphosphonates for the prevention of skeletal-related events.
Ian R, Reid, Tim, Cundy
+11 more sources
Treatment of Osteonecrosis of the Jaw
Journal of Craniofacial Surgery, 2015The definition of bisphosphonate-related osteonecrosis of the jaw (BRONJ) was recently broadened and it is now known as medication-related osteonecrosis of the jaw (MRONJ). To date, the management of MRONJ is controversial. Conservative treatment is recommended, but it is difficult to successfully treat stage 3 MRONJ. Administration of teriparatide for
Eiki, Yamachika +5 more
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Bisphosphonate-related osteonecrosis of the jaws
Stomatologiya, 2022The number of patients with metabolic osteopathies and oncological diseases occurring with the formation of bone metastases is constantly growing and requires special attention not only of oncologists, but also maxillofacial surgeons, dental surgeons and periodontists, due to severe complications from the oral cavity, against the background of ...
V.V. Sogacheva, V.A. Syomkin
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Bisphosphonate-associated osteonecrosis of the jaw
Menopause International, 2007The term 'osteonecrosis of the jaw' is typically used to describe the exposure of bone within the oral cavity. These lesions are often painful and can result in pathological fracture and disfigurement in severe cases. Infection and dental extractions commonly precede presentation, although lesions can occur spontaneously.
Neil, Basu, David M, Reid
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Axitinib-related osteonecrosis of the jaw
Oral Surgery, Oral Medicine, Oral Pathology and Oral Radiology, 2017Tyrosine kinase inhibitors (TKIs) are oral chemotherapy drugs used primarily to treat leukemias, renal cell carcinomas, gastrointestinal stromal tumors, and neuroendocrine tumors. Within this group, a number of drugs have already been implicated in jaw necrosis.
Vinod, Patel +3 more
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Biophosphonate-Related Osteonecrosis of the Jaws
Dental Clinics of North America, 2008In 2003 and 2004, the first reports of patients who developed necrosis of the jawbones while taking biophosphonates appeared in literature; most patients were on this drug for treatment of cancer and some osteoporosis. Since then, more than 500 cases have been identified and the number of these cases continues to grow.
Salvatore L, Ruggiero, Sook-Bin, Woo
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Bisphosphonate-Related Osteonecrosis of the Jaw
Annals of Plastic Surgery, 2020Objectives Antiresorptive agents for bone pain were widely used to treat patients with advanced osteoporosis, multiple myeloma, and bone metastatic cancer. In recent years, however, bisphosphonate-related osteonecrosis of the jaw (BRONJ) has been a rare but major complication of this therapy.
Hsin-I, Chien +6 more
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Drug induced osteonecrosis of the jaw
Cancer Treatment Reviews, 2015Despite the widespread use of bisphosphonates and their unequivocal efficacy for the treatment of various disease states, osteonecrosis of the jaw remains one of the most feared complications associated with their use. Current evidence, however, suggests that there is also a relationship between occurrence of osteonecrosis of the jaw and use of other ...
Issam S, Hamadeh +2 more
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2010
Osteonecrosis of the jaw (ONJ), defined as an oral soft tissue defect with superficial necrosis of the underlying exposed bone, is a severe but uncommon side effect of bisphosphonates (BP). ONJ typically follows a mucosal injury, such as a dental extraction. The exact incidence is unknown but seems to range between 3 and 4%.
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Osteonecrosis of the jaw (ONJ), defined as an oral soft tissue defect with superficial necrosis of the underlying exposed bone, is a severe but uncommon side effect of bisphosphonates (BP). ONJ typically follows a mucosal injury, such as a dental extraction. The exact incidence is unknown but seems to range between 3 and 4%.
openaire +1 more source