Medication-Related Osteonecrosis: Why the Jawbone?
Dentistry Journal, 2023 Medication-related osteonecrosis of the jaw (MRONJ) has emerged as a complication of anti-resorptive medications. Despite its low incidence rate, this problem has gained attention in recent years due to its devastating consequences and lack of preventive
Sydney Kuehn +2 more
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Challenges and Controversies in the Diagnosis of MRONJ [PDF]
, 2019 Medication-related osteonecrosis of the jaw (MRONJ) is a relatively rare but potentially seriousand debilitating complication [...
Campisi, Giuseppina, Fede, Olga Di
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Cost-utility of adjuvant zoledronic acid in patients with breast cancer and low estrogen levels [PDF]
, 2015 BACKGROUND: Adjuvant zoledronic acid (za) appears to improve disease-free survival (dfs) in women with early-stage breast cancer and low levels of estrogen (lle) because of induced or natural menopause.
Lamond, Nathan W D +3 more
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Journal of Medical Case Reports, 2011 Introduction Osteonecrosis of the jaw is a serious side effect in patients receiving nitrogen-containing bisphosphonates intravenously due to malignant diseases.
Ehrenfeld Michael +3 more
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Histology of the Oral Mucosa in Patients With BRONJ at III Stage: A Microscopic Study Proves the Unsuitability of Local Mucosal Flaps. [PDF]
, 2013 BACKGROUND: Bisphosphonate Osteonecrosis of the Jaw (BRONJ) is a newly recognized condition reported in patients treated with aminobisphosphonates (BF).
CORDOVA, Adriana +3 more
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The Validity of Claims-Based Algorithms to Identify Serious Hypersensitivity Reactions and Osteonecrosis of the Jaw. [PDF]
PLoS ONE, 2015 Validation of claims-based algorithms to identify serious hypersensitivity reactions and osteonecrosis of the jaw has not been performed in large osteoporosis populations.
Nicole C Wright +7 more
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Prophylaxis and antibiotic therapy in management protocols of patients treated with oral and intravenous bisphosphonates [PDF]
, 2017 Osteonecrosis of the jaw (MRONJ) linked to bisphosphonate treatment has specific characteristics that render its therapeutic management challenging for clinicians.
Bermúdez Bejarano, Elena Beatriz +6 more
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Osteonecrosis of the jaw in a patient under treatment of osteoporosis with oral bisphosphonate
Autopsy and Case Reports, 2021 Although uncommon in patients under oral therapy, bisphosphonate-related osteonecrosis of the jaw (BRONJ) can be a very severe issue. Early intervention with surgical resection should be the preferable method of treating any stage of the disease ...
Marília A. Figueiredo +2 more
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SNX10 gene mutation leading to osteopetrosis with dysfunctional osteoclasts [PDF]
, 2017 Acknowledgements We sincerely thank the patients and family members who participated in this study. We would also like to thank Stefan Esher, Umeå University, for help with genealogy, and Anna Westerlund for excellent technical assistance.
Ameur, Adam +15 more
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Endokrynologia Polska, 2011 The paper concerns osteonecrosis of the jaw (ONJ). It is a rare but serious clinical condition. It can develop in patients treated in oncologic doses with bisphosphonates but also with denosumab. In osteoporosis ONJ seems to be very rare. Definition, pathogenesis, risk factors, prevention and treatment, and the frequency of ONJ are presented.
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