Results 71 to 80 of about 22,928 (253)
Cell Proliferation, EarlyView.Schematic summarizing the pathway of sSema4D from γδ T cells inhibiting osteoblast differentiation in BRONJ. ABSTRACT Bisphosphonate‐related osteonecrosis of the jaw (BRONJ) is a severe complication in patients undergoing long‐term bisphosphonate therapy, while our knowledge on the pathogenesis of BRONJ is far from sufficient.
Lingling Ou +15 more
wiley +1 more source
Adalimumab: Another Medication Related to Osteonecrosis of the Jaws?
Case Reports in Dentistry, 2016 Objective. The acronym MRONJ has been created in order to identify “Medication-Related Osteonecrosis of the Jaw,” observed after the use of Bisphosphonates, RANK ligand inhibitor, and antiangiogenic medications. Only a case of osteonecrosis of the jaw in
Andrea Cassoni +8 more
doaj +1 more source
Updates on osteonecrosis of the jaw [PDF]
Current Opinion in Supportive & Palliative Care, 2010 Osteonecrosis of the jaw (ONJ) is an uncommon condition noted to occur in patients with cancer who are receiving intravenous bisphosphonates. The cause of ONJ remains unknown. The leading hypotheses addressing the mechanism of ONJ are reviewed here.The present clinical data suggest that ONJ may occur in approximately 5% of patients with metastatic bone
Junro, Yamashita +2 more
openaire +2 more sources
European Journal of Dental Education, EarlyView.ABSTRACT Introduction ONCOllab is a social media application developed by FDI to improve the management of oral complications that may arise during cancer therapy. This study aimed to evaluate the effects of ONCOllab on learning and perception among dental students.
Sara Samur Erguven +3 more
wiley +1 more source
Dental extraction following zoledronate, induces osteonecrosis in rat´s jaw [PDF]
, 2017 Bisphosphonate-Related Osteonecrosis of the Jaw (BRONJ) is clinically characterized by the presence of exposed bone in the oral cavity that persists for more than eight weeks.
Gaitán Cepeda, Luis Alberto +2 more
core +1 more source
BMC Oral HealthIntroduction Medication-related osteonecrosis of the Jaw (MRONJ) is a serious side effect of bone-modifying agents (BMAs), including bisphosphonates, denosumab, and antiangiogenic drugs.
R. Mauceri +5 more
doaj +1 more source
Maxillary osteonecrosis linked to Pembrolizumab therapy: a case report
Journal of Oral Medicine and Oral SurgeryIntroduction: Osteonecrosis of the jaw is a serious condition often associated with the use of bone-modifying agents or antiangiogenics. Recent evidence suggests that immune checkpoint inhibitors, including Pembrolizumab, might also contribute to ...
Gosselin-Rousselle Louise +4 more
doaj +1 more source
European Journal of Oral Sciences, EarlyView.Abstract This study investigated how chronic metformin administration modulates the cellular profile and inflammatory markers in a zoledronic acid‐based rat model of medication‐related osteonecrosis of the jaw (MRONJ). Male Wistar rats were allocated to different treatments: (i) naïve, (ii) MRONJ (zoledronic acid, 0.2 mg/kg, i.v.
Liviane Maria Alves Rabelo +10 more
wiley +1 more source
Fatal spinal cord compression in a horse with chronic actinobacterial cranial nuchal bursitis
Equine Veterinary Education, EarlyView.Summary A 14‐year‐old warmblood gelding was managed for waxing and waning cranial nuchal bursitis for 2 years. Intensive medical and surgical management was not curative, and the patient was subjected to euthanasia after becoming acutely recumbent. Ante‐mortem and post‐mortem next generation sequencing of bursal tissue and post‐mortem conventional PCR ...
H. Mesch +4 more
wiley +1 more source
Bisphosphonate-Related Osteonecrosis of the Jaw Mimicking Bone Metastasis
Case Reports in Oncological Medicine, 2014 Osteonecrosis of the jaw is usually a potential complication of bisphosphonate therapy. In a cancer patient, this disease entity can be misdiagnosed as a metastatic lesion. Our aim is to make clinicians aware of bisphosphonate associated osteonecrosis of
Geetika Bhatt +4 more
doaj +1 more source