Osteonectin bidirectionally regulates osteoblast mineralization
Objective The aim of this study was to investigate whether Osteonectin/Secreted protein acidic and rich in cysteine (ON/SPARC) had a two-way dose-dependent regulatory effect on osteoblast mineralization and its molecular mechanism.
Yun‑Sen Zhu +3 more
doaj +3 more sources
Osteonectin as a screening marker for pancreatic cancer: A prospective study [PDF]
Objective Osteonectin plays a central role in various processes during the development of pancreatic adenocarcinoma. This prospective pilot study was performed to determine the feasibility of serum osteonectin as a screening tool for pancreatic cancer ...
Angeliki Papapanagiotou +7 more
doaj +4 more sources
Preparation and characterization of decellularized bovine bone as a bioscaffold for bone tissue engineering applications [PDF]
Objective(s): This study aimed to develop and evaluate decellularized bovine bone (DBB) scaffolds and investigate their potential to promote osteogenic differentiation when combined with Crocin and Alendronate.Materials and Methods: Bovine bone was ...
Roya Akbarpour +3 more
doaj +2 more sources
Structure and Expression of Osteonectin Mrna in Human Tissue [PDF]
A cDNA encoding osteonectin was isolated from a human bone cell cDNA library and used to examine osteonectin protein structure, mRNA structure and expression in human tissue. The deduced protein sequence shows complete identity with a recently isolated placental form and extensive homology to mouse and bovine counterparts.
Marian Young +2 more
exaly +4 more sources
Propolis nanoemulsion and mesenchymal stem cell conditioned medium promote osteoblastogenesis against lipopolysaccharide-induced osteolysis in hyperglycemic rats [PDF]
Hyperglycemia is known to worsen lipopolysaccharide (LPS)-induced inflammatory osteolysis. However, regenerative therapy with human umbilical cord mesenchymal stem cells conditioned medium (HUCMSCs-CM) and Tetragonula biroi propolis nanoemulsion (PNE ...
Ananto Ali Alhasyimi +7 more
doaj +2 more sources
Background The role of adipokine dysregulation in determining the metabolic fate of obesity is not well studied. We aimed to examine whether the matricellular protein osteonectin and the profiles of certain adipokines could differentiate metabolically ...
Shan Gao, Steven Willi
exaly +3 more sources
Teriparatide facilitates osteogenic differentiation of bone mesenchymal stem cells to alleviate idiopathic osteoporosis via the circFNDC3B-miR-125a-5p-GLS axis [PDF]
Osteoporosis (OP), a systemic bone disease, is characterized by degeneration of bone microstructure and susceptibility to fracture. Teriparatide (TPD) is an active fragment of human endogenous parathyroid hormone which has been revealed to promote ...
Jiaxin Fu +3 more
doaj +2 more sources
Estimation of the Therapeutic Effect of Diode Laser on Bone Cells in Mandibular Distraction Osteogenesis: An Experimental Study in Adult Male Rabbits [PDF]
Background: The use of the intraoral distractors has been associated with different drawbacks resulting in their untimely removal and treatment relapse.Objective: This study aimed to estimate the therapeutic effect of diode laser on bone cells in the ...
Akram Abdelaal, Fatma Saad
doaj +1 more source
The literature review highlights the results of the most recent foreign and Russian studies on topical problems of vascular calcification with an emphasis on the relationship between some biochemical markers of vascular calcification (in priority ...
N. A. Maslatsov, Yu. I. Ragino
doaj +1 more source
Bonebiomarkers in Periodontal Disease: A Review Article [PDF]
Periodontitis, is an inflammatory state of the tooth supporting structures and if left untreated, the disease continues to progressive bone destruction and subsequent tooth loss.
V. Shankar Ram +4 more
doaj +1 more source

