Results 41 to 50 of about 7,635 (213)

Basic fibroblast growth factor destabilizes osteonectin mRNA in osteoblasts

open access: yes, 1998
Osteonectin (secreted protein acidic and rich in cysteine, 40-kDa basement membrane) is a glycoprotein abundantly expressed in bone and in other tissues undergoing active remodeling.
Anne M. Delany, Ernesto Canalis
core   +1 more source

The evaluation of peri-implant sulcus fluid osteocalcin, osteopontin, and osteonectin levels in peri-implant diseases

open access: yes, 2018
Background: Peri-implant mucositis is an inflammation of the soft tissues surrounding an implant. Peri-implantitis refers to a process characterized by peri-implant bone loss along with an inflammation of the soft tissues.
Cakal O.T., Efeoglu C., Bozkurt E.
core   +2 more sources

Immunolocalization of osteonectin in avian tibial dyschondroplastic cartilage [PDF]

open access: yesDevelopmental Dynamics, 1996
Osteonectin is an acidic calcium-binding protein found in cartilage, bone matrix, vascular endothelium, and areas of tissue repair. Using immunocytochemistry, osteonectin has been localized in all zones of the normal avian epiphyseal growth plate with notably high amounts in the hypertrophic zone.
J, Wu   +4 more
openaire   +2 more sources

The profiling and analysis of gene expression in human periodontal ligament tissue and fibroblasts

open access: yesClinical and Experimental Dental Research, 2022
Objectives The periodontal ligament (PDL) is an important component of periodontium to support dental structure in the alveolar socket. Regeneration of PDL tissue is an effective treatment option for periodontal disease and the profiling of genes ...
Nattakarn Hosiriluck   +4 more
doaj   +1 more source

A Fully Human Engineered Bone Niche With Endogenous Osteoclastogenesis Reveals Osteoclast‐Dependent Osteomimicry in Prostate Cancer Cells

open access: yesAdvanced Healthcare Materials, EarlyView.
A human 3D bone niche integrating osteoblasts and osteoclasts enables co‐culture with prostate cancer cell lines and patient‐derived organoids. The engineered niche (i) models aspects of reciprocal phenotypic regulation between osteoblasts and cancer cells, (ii) captures osteoclast‐enhanced osteomimicry in tumor cells, and (iii) establishes a ...
Andrea Mazzoleni   +7 more
wiley   +1 more source

Adipokines in Obese Asthma: A Complex Relationship Influenced More by Sex, Weight, and Oral Steroid Treatment Than Disease Severity

open access: yesAllergy, EarlyView.
Adipokine secretion from adipose tissue may be involved in obesity‐related asthma, but it is unknown how adipokine levels relate to asthma characteristics. Plasma adipokines were measured in well‐characterized lean, overweight or obese patients with mild‐to‐moderate or severe asthma.
Lars I. Andersson   +20 more
wiley   +1 more source

Exploring the Role of Serum Osteonectin and Hsp27 in Pediatric MAFLD Diagnosis and Cardiometabolic Health. [PDF]

open access: yesNutrients
Background: Childhood obesity is one of the major challenges of public health policies. The problem of fatty liver in childhood, known as MAFLD (metabolic dysfunction-associated fatty liver disease), is of particular interest as the gold standard ...
Bălănescu A   +6 more
europepmc   +2 more sources

Osteonectin (SPARC) Expression in Vascular Calcification : In Vitro and Ex Vivo Studies

open access: yes, 2016
Osteonectin, also termed SPARC, is a noncollagenous protein of bone matrix. Since there are controversial results regarding its role during the process of vascular calcification, we investigated osteonectin expression in our in vitro calcification model.
L. Cappelletti   +6 more
core   +1 more source

A guide to the types, structures, and multifaceted functions of matrix metalloproteinases in cancer

open access: yesThe FEBS Journal, EarlyView.
Matrix metalloproteinases (MMPs) orchestrate cancer progression and metastasis through proteolytic and non‐proteolytic actions. By remodeling the tumor microenvironment, enhancing growth factor availability, and modulating cell behavior, MMPs promote proliferation, migration or invasion, and epithelial‐to‐mesenchymal transition. Alongside extracellular
Zoi Piperigkou   +4 more
wiley   +1 more source

Trafficking of osteonectin by retinal pigment epithelial cells: Evidence for basolateral secretion

open access: yes, 2007
Osteonectin is a glycoprotein that modulates several aspects of cellular behaviour including proliferation and adhesion. The retinal pigment epithelium forms a continuous monolayer of polarised cells immediately bellow the neuroretina, and is integral to
Spiller, Dave G.; id_orcid   +7 more
core   +1 more source

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