Results 91 to 100 of about 32,260 (226)

Systemic, Lifestyle and Environmental Modifying Factors in the Pathogenesis of Periodontitis

open access: yesJournal of Periodontal Research, EarlyView.
A variety of impacting factors in the pathogenesis of periodontitis exist, including systemic, lifestyle, and environmental factors. This review highlights the manifold mechanistic aspects of the link between the pathogenesis of periodontitis, addressing these numerous factors to supplement the long‐standing knowledge of the progression of the disease.
Groeger Sabine Elisabeth   +5 more
wiley   +1 more source

The Function of Naringin in Inducing Secretion of Osteoprotegerin and Inhibiting Formation of Osteoclasts

open access: yesEvidence-Based Complementary and Alternative Medicine, 2016
Osteoporosis has become one of the most prevalent and costly diseases in the world. It is a metabolic disease characterized by reduction in bone mass due to an imbalance between bone formation and resorption.
Tong Xu   +5 more
semanticscholar   +1 more source

Stem Cells From Dental Pulp, Periodontal Tissues, and Other Oral Sources: Biological Concepts and Regenerative Potential

open access: yesJournal of Periodontal Research, EarlyView.
A graphical abstract recapping the different sources of dental, periodontal, and other oral‐derived mesenchymal stromal cells (MSCs) and their regenerative mechanisms and potentials. The review's article findings bridge fundamental biological science with translational advances, highlighting the significance of MSCs in craniofacial regenerative ...
Karim M. Fawzy El‐Sayed   +6 more
wiley   +1 more source

Osteoprotegerin Is a Receptor for the Cytotoxic Ligand TRAIL*

open access: yesJournal of Biological Chemistry, 1998
TRAIL is a tumor necrosis factor-related ligand that induces apoptosis upon binding to its death domain-containing receptors, DR4 and DR5. Two additional TRAIL receptors, TRID/DcR1 and DcR2, lack functional death domains and function as decoy receptors ...
J. Emery   +14 more
semanticscholar   +1 more source

Inflammatory and Immunological Basis of Periodontal Diseases

open access: yesJournal of Periodontal Research, EarlyView.
The periodontal lesion emerges as an evolving immunological battlefield, where host–microbiome interactions, dysregulated immune responses, fragile resolution mechanisms, and inflammophilic dysbiosis converge to shift the balance from homeostasis to unrestrained tissue destruction.
Giacomo Baima   +3 more
wiley   +1 more source

Heparan Sulfate Regulates the Structure and Function of Osteoprotegerin in Osteoclastogenesis*

open access: yesJournal of Biological Chemistry, 2016
Osteoprotegerin (OPG), a decoy receptor secreted by osteoblasts, is a major negative regulator of bone resorption. It functions by neutralizing the receptor activator of nuclear factor κB ligand (RANKL), which plays a central role in promoting ...
Miaomiao Li, Shuying Yang, Ding Xu
semanticscholar   +1 more source

Randomised Clinical Trial on the Effect of Intermittent Vibrational Force Application During Orthodontic Treatment With Aligners on Root Resorption

open access: yesOrthodontics &Craniofacial Research, EarlyView.
ABSTRACT Objective The aim of this RCT was to analyse the relationship between intermittent vibratory forces and external apical root resorption (EARR) in patients treated with clear aligners, building on prior research on vibrational effects on biomarkers.
Leonardo Teti   +5 more
wiley   +1 more source

The role of acquired host immunity in periodontal diseases

open access: yesPeriodontology 2000, EarlyView.
Abstract The aim of this narrative review is to relate the contribution of European researchers to the complex topic of the host immune system in periodontal disease, focusing on acquired immunity. Other chapters in this volume will address the genetics and autoantibody responses and other forms of immunity to periodontal disease.
Denis F. Kinane   +2 more
wiley   +1 more source

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