Amelogenin Peptide Extract Increases Differentiation and Angiogenic and Local Factor Production and Inhibits Apoptosis in Human Osteoblasts [PDF]
, 2013 Enamel matrix derivative (EMD), a decellularized porcine extracellular matrix (ECM), is used clinically in periodontal tissue regeneration. Amelogenin, EMD’s principal component, spontaneously assembles into nanospheres in vivo, forming an ECM complex ...
Almaguer-Flores, Argelia +6 more
core +2 more sources
The association of osteoprotegerin and RANKL with osteoporosis: a systematic review with meta-analysis [PDF]
, 2023 Guanghao Chi +4 more
openalex +1 more source
Expression of osteoprotegerin and its ligands, RANKL and TRAIL, in rheumatoid arthritis
Scientific Reports, 2016 Osteoprotegerin (OPG), receptor activator of nuclear factor-ΚB ligand (RANKL) and tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) have been involved in rheumatoid arthritis (RA) pathophysiology.
S. Remuzgo-Martínez +10 more
semanticscholar +1 more source
Periodontology 2000, EarlyView.Abstract Background Understanding periodontal diseases through a biological lens has been a central aim in periodontal research. Visionary pioneers in the field established the foundations of our knowledge, providing invaluable insights into disease mechanisms and progression.
Nagihan Bostanci +2 more
wiley +1 more source
A virtual approach to evaluate therapies for management of multiple myeloma induced bone disease: Modelling Therapies for Multiple Myeloma Induced Bone Disease [PDF]
, 2015 Multiple myeloma bone disease is devastating for patients and a major cause of morbidity. The disease leads to bone destruction by inhibiting osteoblast activity while stimulating osteoclast activity.
Fagan, Michael J. +2 more
core +2 more sources
Malaysian Orthopaedic Journal, 2018 Introduction: Osteoporosis (OP) is a major health problem in the older population. The aim of the study was to assess the role of serum osteoprotegerin (OPG) as a diagnostic indicator of primary osteoporosis in peri- and post-menopausal women in an ...
A. Pandey +4 more
semanticscholar +1 more source
Antibiotic‐mediated immune modulation in periodontitis
Periodontology 2000, EarlyView.Abstract Periodontitis is a chronic inflammatory disease affecting the supporting structures of the teeth. Although initiated by dysbiotic microbial communities, its progression is largely driven by the host's uncontrolled inflammatory response. While antibiotics have conventionally been employed in periodontitis therapy for their antimicrobial ...
Lina J. Suárez +6 more
wiley +1 more source
Autoantibodies to Osteoprotegerin are Associated with Low Hip Bone Mineral Density and History of Fractures in Axial Spondyloarthritis: A Cross-Sectional Observational Study [PDF]
, 2017 Osteoporosis is a recognised complication of axial spondyloarthritis (axSpA) and is thought to be due to functional impairment and the osteoclast-activating effects of proinflammatory cytokines.
A Real +29 more
core +2 more sources
Heparan Sulfate Regulates the Structure and Function of Osteoprotegerin in Osteoclastogenesis*
Journal of Biological Chemistry, 2016 Osteoprotegerin (OPG), a decoy receptor secreted by osteoblasts, is a major negative regulator of bone resorption. It functions by neutralizing the receptor activator of nuclear factor κB ligand (RANKL), which plays a central role in promoting ...
Miaomiao Li, Shuying Yang, Ding Xu
semanticscholar +1 more source