Results 11 to 20 of about 32,260 (226)

Extracellular vesicles from adipose tissue‐derived stem cells alleviate osteoporosis through osteoprotegerin and miR‐21‐5p

open access: yesJournal of Extracellular Vesicles, 2021
Osteoporosis is one of the most common skeletal disorders caused by the imbalance between bone formation and resorption, resulting in quantitative loss of bone tissue.
Kyoung Soo Lee   +15 more
doaj   +2 more sources

Osteoprotegerin Is Associated With Major Bleeding But Not With Cardiovascular Outcomes in Patients With Acute Coronary Syndromes: Insights From the PLATO (Platelet Inhibition and Patient Outcomes) Trial

open access: yesJournal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2018
Background Elevated levels of osteoprotegerin, a secreted tumor necrosis factor–related molecule, might be associated with adverse outcomes in patients with coronary artery disease. We measured plasma osteoprotegerin concentrations on hospital admission,
Thor Ueland   +12 more
doaj   +2 more sources

Association of osteocalcin, osteoprotegerin, and osteopontin with cardiovascular disease and retinopathy in type 2 diabetes [PDF]

open access: hybridDiabetes/Metabolism Research Reviews, 2023
Novel biomarkers of vascular disease in diabetes could help identify new mechanistic pathways. Osteocalcin, osteoprotegerin, and osteopontin are key molecules involved in bone and vascular calcification processes, both of which are compromised in ...
Ernesto Maddaloni   +19 more
openalex   +2 more sources

Activated T cells regulate bone loss and joint destruction in adjuvant arthritis through osteoprotegerin ligand [PDF]

open access: bronzeNature, 1999
Young‐Yun Kong   +20 more
openalex   +2 more sources

RANKL/RANK is required for cytokine-induced beta cell death; osteoprotegerin, a RANKL inhibitor, reverses rodent type 1 diabetes

open access: yesScience Advances, 2023
Treatment for type 1 diabetes (T1D) requires stimulation of functional β cell regeneration and survival under stress. Previously, we showed that inhibition of the RANKL/RANK [receptor activator of nuclear factor kappa Β (NF-κB) ligand] pathway, by ...
N. G. Kondegowda   +11 more
semanticscholar   +1 more source

Two Consecutive Days of Extreme Conditioning Program Training Affects Pro and Anti-inflammatory Cytokines and Osteoprotegerin without Impairments in Muscle Power [PDF]

open access: goldFrontiers in Physiology, 2016
The aim of this study was to investigate the effects of two consecutive extreme conditioning program training sessions (24 h apart) designed to enhance work-capacity that involved both cardiovascular and muscular exercises on cytokines, muscle power ...
Ramires Alsamir Tibana   +11 more
openalex   +2 more sources

The roles of osteoprotegerin in cancer, far beyond a bone player

open access: yesCell Death Discovery, 2022
Osteoprotegerin (OPG), also known as tumor necrosis factor receptor superfamily member 11B (TNFRSF11B), is a member of the tumor necrosis factor (TNF) receptor superfamily.
Yufei Wang   +4 more
semanticscholar   +1 more source

Osteoprotegerin and Ischemic Stroke Prognosis: A Prospective Multicenter Study and Mendelian Randomization Analysis

open access: yesStroke, 2022
Background: Osteoprotegerin was implicated in vascular injury and inflammatory responses, but its prognostic value in ischemic stroke remained unclear.
Zhengbao Zhu   +11 more
semanticscholar   +1 more source

Osteoprotegerin-dependent M cell self-regulation balances gut infection and immunity

open access: yesNature Communications, 2020
Microfold cells (M cells) are responsible for antigen uptake to initiate immune responses in the gut-associated lymphoid tissue (GALT). Receptor activator of nuclear factor-κB ligand (RANKL) is essential for M cell differentiation.
S. Kimura   +14 more
semanticscholar   +1 more source

Prognostic Value of Serum Osteoprotegerin Level in Patients With Hepatocellular Carcinoma Following Surgical Resection

open access: yesFrontiers in Oncology, 2021
BackgroundMultiple studies have reported that tissue or serum osteoprotegerin (OPG) level is a prognostic factor for patients with cancer. However, little is known about the role of serum OPG in hepatocellular carcinoma (HCC).
Chihao Zhang   +10 more
doaj   +1 more source

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