Results 21 to 30 of about 32,260 (226)

Pathogenetic and diagnostic role of osteoprotegerin in the combined course of osteoarthritis and obesity

Journal of Education, Health and Sport, 2022
In recent years, it has been proven that the formation of OA can occur against the background of impaired bone metabolism. Bone remodeling is considered as a continuous complex process aimed at eliminating microdamages and updating the bone matrix. A
A. Litvynova, L. Pasiieshvili
doaj   +1 more source

Incorporation of Bone Morphogenetic Protein-2 and Osteoprotegerin in 3D-Printed Ti6Al4V Scaffolds Enhances Osseointegration Under Osteoporotic Conditions

Frontiers in Bioengineering and Biotechnology, 2021
Osteoporosis is an age-related metabolic disease that results in limited bone regeneration capacity and excessive osteoclast activity. After arthroplasty in patients with osteoporosis, poor interface osseointegration resulting from insufficient bone ...
Xianggang Wang, Xianggang Wang, Zhengyan Li, Zhengyan Li, Zhonghan Wang, Zhonghan Wang, He Liu, He Liu, Yutao Cui, Yutao Cui, Yuzhe Liu, Yuzhe Liu, Ming Ren, Ming Ren, Hongsheng Zhan, Hongsheng Zhan, Zuhao Li, Zuhao Li, Minfei Wu, Minfei Wu, Jincheng Wang, Jincheng Wang   +21 more
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The tooth eruption and its abnormalities - A narrative review

SRM Journal of Research in Dental Sciences, 2022
Background: The process of tooth eruption is influenced by local, systemic, and genetic factors. Any disturbances in these factors might lead to abnormalities in the eruption of the tooth.
K V Sai Charan, R Sangeetha, N Santana, G Hema Priya, M Kumari, P Murali, V S Gayathri   +6 more
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osteoprotegerin-deficient mice develop early onset osteoporosis and arterial calcification.

Genes & Development, 1998
Osteoprotegerin (OPG) is a secreted protein that inhibits osteoclast formation. In this study the physiological role of OPG is investigated by generating OPG-deficient mice.
N. Bucay, I. Sarosi, C. Dunstan, S. Morony, J. Tarpley, C. Capparelli, S. Scully, H. Tan, Wei-wei Xu, D. Lacey, W. J. Boyle, W. S. Simonet   +11 more
semanticscholar   +1 more source

Association of serum osteoprotegerin with vascular calcification in patients with type 2 diabetes

Cardiovascular Diabetology, 2013
Background Osteoprotegerin is a member of the tumor necrosis factor-related family and inhibits RANK stimulation of osteoclast formation as a soluble decoy receptor.
Aoki Atsushi, Murata Miho, Asano Tomoko, Ikoma Aki, Sasaki Masami, Saito Tomoyuki, Otani Taeko, Jinbo Sachimi, Ikeda Nahoko, Kawakami Masanobu, Ishikawa San-e   +10 more
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The Role of Osteoprotegerin and Its Ligands in Vascular Function

International Journal of Molecular Sciences, 2019
The superfamily of tumor necrosis factor (TNF) receptors includes osteoprotegerin (OPG) and its ligands, which are receptor activators of nuclear factor kappa-B ligand (RANKL) and TNF-related apoptosis-inducing ligand (TRAIL).
L. Rochette, A. Méloux, E. Rigal, M. Zeller, Y. Cottin, C. Vergely   +5 more
semanticscholar   +1 more source

Impact of Alirocumab on Release Markers of Atherosclerotic Plaque Vulnerability in Patients with Mixed Hyperlipidemia and Vulnerable Atherosclerotic Plaque

Medicina, 2022
Background and Objectives: Atherosclerosis is a disease in the pathogenesis of which plasma factors apart from elevated cholesterol levels play a keyrole. Such factors include osteopontin (OPN), osteoprotegerin (OPG), and metalloproteinases (MMPs), which
Michał Kosowski, Marcin Basiak, Marcin Hachuła, Bogusław Okopień   +3 more
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Risk Factors Associated With Altered Circulating MicroRNA‐125b and Their Influences on Uremic Vascular Calcification Among Patients With End‐Stage Renal Disease

Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2019
Background MicroRNA‐125b (miR‐125b) has been shown to regulate vascular calcification (VC), and serum miR‐125b levels are a potential biomarker for estimating the risk of uremic VC status.
Chia‐Ter Chao, Tzu‐Hang Yuan, Hsiang‐Yuan Yeh, Hsuan‐Yu Chen, Jenq‐Wen Huang, Huei‐Wen Chen   +5 more
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Relationship between serum osteoprotegerin and vascular calcifications in hemodialysis patients

The Egyptian Heart Journal, 2017
Background: Uremia is a vasculopathic process, and both cardiac calcification and vascular calcification seen from the early stages of chronic kidney disease.
Tarek Z. El Baz, Osama A. Khamis, Amal El-Shehaby, Hussein Chahine, Ahmad Alaa Al-Din Ahmed, Mostafa A. Alsawasany   +5 more
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Osteoprotegerin Promotes Liver Steatosis by Targeting the ERK–PPAR-γ–CD36 Pathway

Diabetes, 2019
Previous cross-sectional studies have established that circulating osteoprotegerin (OPG) levels are associated with nonalcoholic fatty liver disease (NAFLD). However, the role of OPG in metabolic diseases, such as diabetes and NAFLD, is still unclear. In
Cheng Zhang, Xiaohe Luo, Jianrong Chen, Baoyong Zhou, Mengliu Yang, Rui Liu, Dongfang Liu, H. Gu, Zhiming Zhu, Hongting Zheng, Lingou Li, Gangyi Yang   +11 more
semanticscholar   +1 more source