Results 41 to 50 of about 53,476 (305)

Role of osteoprotegerin/receptor activator of nuclear factor kappa B/receptor activator of nuclear factor kappa B ligand axis in nonalcoholic fatty liver disease [PDF]

, 2018
Concomitantly with the increase in the prevalences of overweight/obesity, nonalcoholic fatty liver disease (NAFLD) has worldwide become the main cause of chronic liver disease in both adults and children.
Andreoli, Gian Marco, D’Avanzo, Miriam, Mitri, Delia De, Pacifico, Lucia, Pierimarchi, Pasquale   +4 more
core   +1 more source

Serum osteoprotegerin and renal osteodystrophy [PDF]

Nephrology Dialysis Transplantation, 2002
Numerous growth factors and cytokines are known to modulate bone turnover. An important, recently discovered complex involved in osteoclastogenesis is the osteoprotegerin/osteoprotegerin-ligand (OPG/OPGL) cytokine complex, which is produced by osteoblasts.
Coen, Giorgio, Ballanti, Paola, Balducci, Alessandro, Calabria, Santo, Fischer, Maria Stephanie, Jankovic, Ljiljana, Manni, Micaela, Morosetti, Massimo, Moscaritolo, Eleonora, Sardella, Daniela, Bonucci, Ermanno   +10 more
openaire   +3 more sources

Osteoprotegerin Is Associated With Major Bleeding But Not With Cardiovascular Outcomes in Patients With Acute Coronary Syndromes: Insights From the PLATO (Platelet Inhibition and Patient Outcomes) Trial

Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2018
Background Elevated levels of osteoprotegerin, a secreted tumor necrosis factor–related molecule, might be associated with adverse outcomes in patients with coronary artery disease. We measured plasma osteoprotegerin concentrations on hospital admission,
Thor Ueland, Axel Åkerblom, Tatevik Ghukasyan, Annika E. Michelsen, Pål Aukrust, Richard C. Becker, Maria Bertilsson, Anders Himmelmann, Stefan K. James, Agneta Siegbahn, Robert F. Storey, Frederic Kontny, Lars Wallentin   +12 more
doaj   +1 more source

Brucella and Osteoarticular Cell Activation: Partners in Crime [PDF]

, 2017
Osteoarticular brucellosis is the most common presentation of human active disease although its prevalence varies widely. The three most common forms of osteoarticular involvement are sacroiliitis, spondylitis, and peripheral arthritis.
Adamopoulos, Adarichev, Al-Eissa, Aydin, Azuma, Bartok, Behera, Bivi, Bonewald, Burrage, Buzgan, Cenci, Chen, Civitelli, Colmenero, Delpino, Delpino, Delpino, D’Amelio, D’Amelio, El-Jawhari, Farkas, Fuller, Garcia Samartino, Geiger, Giambartolomei, Giambartolomei, Gilmore, Goenka, Goenka, Golding, Gotuzzo, Grundt, Haynes, Horowitz, Ibero, Ikeda, Inman, Karner, Kasim, Kawai, Kitazawa, Kobayashi, Kollet, Kong, Kotake, Lacey, Lampiasi, Lerner, Madkour, Madkour, Magnani, Merkel, Milner, Mori, Nair, Nakayamada, Pappas, Pappas, Pesce Viglietti, Press, Prideaux, Rajapakse, Rajashekara, Rodan, Roggia, Sato, Scian, Scian, Scian, Scian, Shaalan, Skyberg, Soder, Song, Streuli, Takayanagi, Takayanagi, Takayanagi, Tanaka, Teitelbaum, Thomson, Tokoyoda, Turan, Viau, Visnjic, Wallach, Wei, Yasuda, Young, Young, Zhan, Zhan, Zhan, Zhao, Zwerdling   +95 more
core   +1 more source

Osteoprotegerin Promotes Liver Steatosis by Targeting the ERK–PPAR-γ–CD36 Pathway

Diabetes, 2019
Previous cross-sectional studies have established that circulating osteoprotegerin (OPG) levels are associated with nonalcoholic fatty liver disease (NAFLD). However, the role of OPG in metabolic diseases, such as diabetes and NAFLD, is still unclear. In
Cheng Zhang, Xiaohe Luo, Jianrong Chen, Baoyong Zhou, Mengliu Yang, Rui Liu, Dongfang Liu, H. Gu, Zhiming Zhu, Hongting Zheng, Lingou Li, Gangyi Yang   +11 more
semanticscholar   +1 more source

Osteoprotegerin, vascular calcification and atherosclerosis [PDF]

Atherosclerosis, 2009
The association of bone pathologies with atherosclerosis has stimulated the search for common mediators linking the skeletal and the vascular system. Since its initial discovery as a key regulator in bone metabolism, osteoprotegerin (OPG) has become the subject of intense interest for its role in vascular disease and calcification. Studies in vitro and
Golledge, Jonathan, Van Campenhout, Ann
openaire   +3 more sources

Relationship between serum osteoprotegerin and vascular calcifications in hemodialysis patients

The Egyptian Heart Journal, 2017
Background: Uremia is a vasculopathic process, and both cardiac calcification and vascular calcification seen from the early stages of chronic kidney disease.
Tarek Z. El Baz, Osama A. Khamis, Amal El-Shehaby, Hussein Chahine, Ahmad Alaa Al-Din Ahmed, Mostafa A. Alsawasany   +5 more
doaj   +1 more source

Comparative Study of the Cytokine Profiles of Serum and Tissues from Patients with the Ossification of the Posterior Longitudinal Ligament

Biomedicines, 2023
Background: The ossification of the posterior longitudinal ligament (OPLL) is one of the contributing factors leading to severe cervical spondylotic myelopathy (CSM). The mechanism causing ossification is still unclear.
Li-Yu Fay, Chao-Hung Kuo, Hsuan-Kan Chang, Mei-Yin Yeh, Chih-Chang Chang, Chin-Chu Ko, Tsung-Hsi Tu, Yi-Hsuan Kuo, Wang-Yu Hsu, Chien-Hui Hung, Ching-Jung Chen, Jau-Ching Wu, May-Jywan Tsai, Wen-Cheng Huang, Henrich Cheng, Meng-Jen Lee   +15 more
doaj   +1 more source

Osteoprotegerin Is more than a Possible Serum Marker in Liver Fibrosis: A Study into Its Function in Human and Murine Liver

Pharmaceutics, 2020
Osteoprotegerin (OPG) serum levels are associated with liver fibrogenesis and have been proposed as a biomarker for diagnosis. However, the source and role of OPG in liver fibrosis are unknown, as is the question of whether OPG expression responds to ...
Adhyatmika Adhyatmika, Leonie Beljaars, Kurnia S. S. Putri, Habibie Habibie, Carian E. Boorsma, Catharina Reker-Smit, Theerut Luangmonkong, Burak Guney, Axel Haak, Keri A. Mangnus, Eduard Post, Klaas Poelstra, Kim Ravnskjaer, Peter Olinga, Barbro N. Melgert   +14 more
doaj   +1 more source

Pangasius djambal gelatin increases osteoprotegerin, decreases RANK and RANKL after tooth extraction in vivo

Dental Journal, 2023
Background: Osteoprotegerin (OPG) plays a role in preventing osteoclast formation and osteoclastic bone resorption by inhibiting the receptor activator nuclear factor-β and its ligand (RANK–RANKL) interaction that causes bone resorption.
Fredy Mardiyantoro, Nenny Prasetyaningrum, Lukman H. Hidayat, Uswatun Khasanah, Virginia C. Roring, Ahida Muizun, Varellia A. W. Kardikadewi   +6 more
doaj   +1 more source