Results 91 to 100 of about 116,442 (313)
Journal of Bone Oncology, 2021 Osteosarcoma frequently presents as recurrence and metastasis, even if the primary lesion was eradicated and/or radiotherapy and chemotherapy were administered.
Baobiao Zhuo +6 more
doaj
HSP90AA1-mediated autophagy promotes drug resistance in osteosarcoma
Journal of Experimental & Clinical Cancer Research, 2018 Background Osteosarcoma is the most common primary bone tumor in children and adolescents. Unfortunately, osteosarcoma treatments often fail due to the development of chemoresistance, of which the underlying molecular mechanisms still remain unclear.
Xin Xiao +9 more
doaj +1 more source
Predicting Pathogenicity Of nsSNPs Associated With Rb1 -- An In Silico Approach [PDF]
arXiv, 2023 Single nucleotide polymorphisms (SNPs) are variations at specific locations in DNA. Sequence responsible for marking genes associated with diseases or tracking inherited diseases within The family. These variations in the Rb1 gene can cause Retinoblastoma and cancer in the retina Of one eye or both, Osteosarcoma, Melanoma, Leukemias, Lungs, and Breast ...
arxiv
Viridicatol from the Deep‐Sea‐Derived Fungus Alleviates Bone Loss by Targeting the Wnt/SHN3 Pathway
Advanced Science, EarlyView.Viridicatol (VDC), isolated from the deep‐sea‐derived fungus, enhances osteogenesis in vitro and in vivo by targeting Wnt/SHN3 signaling pathway. It can be delivered via engineered nanovesicles to mitigate bone loss of osteoporosis, fracture repair, and osteogenesis imperfecta.
Chun‐Lan Xie +10 more
wiley +1 more source
Cellular Physiology and Biochemistry, 2018 Background/Aims: Gain-of-function of mutant p53 is associated with a high rate of lung metastasis in osteosarcoma. To investigate the mechanism of mutant p53-induced osteosarcoma metastasis, expression array analysis was performed, comparing non ...
Yanqin Zhang +15 more
doaj +1 more source
Advanced Science, EarlyView.An acoustic‐responsive therapeutic platform for synergistic sonopiezoelectric‐gaseous osteosarcoma therapy and bone regeneration is fabricated through the joint loading of few‐layer black phosphorus nanosheets and S‐Nitroso‐L‐glutathione onto the 3D‐printed bioactive glass scaffolds.
Haoyu Fang +8 more
wiley +1 more source
Journal of Surgical Oncology, Volume 127, Issue 1, Page 148-158, January 2023., 2023 Abstract Background Expandable endoprostheses can be used to equalize limb length for pediatric patients requiring reconstruction following large bony oncologic resections. Outcomes of the Compress® Compliant Pre‐Stress (CPS) spindle paired with an Orthopedic Salvage System expandable distal femur endoprosthesis have not been reported.
Kara S. Tanaka +16 more
wiley +1 more source
Advanced Science, EarlyView.This study develops lipid nanoparticles (LNPs) combining cationic and ionizable lipids for efficient cytosolic protein delivery. Optimized LNPs deliver functional proteins, including antibodies, enzymes, and Cas9, with high serum stability and albumin‐mediated endocytosis.
Lanfang Ren +6 more
wiley +1 more source
A Rare Case of Extraskeletal Primary Osteosarcoma of Breast: How We Managed
Asian Journal of Oncology, 2018 Primary osteosarcoma arising in breast is a rare form of extra skeletal osteosarcoma, accounting for less than 1% of all breast cancers and 12.5% of sarcomas arising in breast.
Kailash Chand Sharma +5 more
doaj +1 more source
Biomedical Applications of Gadolinium‐Containing Biomaterials: Not Only MRI Contrast Agent
Advanced Science, EarlyView.This paper summarizes the latest applications and potential mechanisms of the rare earth element gadolinium in biomedical fields, in addition to its traditional application as an MRI contrast agent, including osteogenesis, antimicrobial, antitumor, bioimaging, bioprobes, and so on.
Xingtong Pan +9 more
wiley +1 more source