Results 111 to 120 of about 171,941 (345)
Concurrent Germline RB1 & Mosaic TP53 in a Child With Multiple Childhood Cancers
American Journal of Medical Genetics Part A, EarlyView.ABSTRACT We report a patient with a pathogenic germline variant (PGV) in RB1 and somatic mosaicism for a pathogenic TP53 variant who developed three distinct types of childhood cancer: retinoblastoma, osteosarcoma, and myelodysplastic syndrome (MDS) before the age of 6 years.
Ole Haubjerg Nielsen +8 more
wiley +1 more source
Global hub genes within the osteosarcoma network.
, 2015 The table lists the top 5% of genes with the highest number of interactions in the OS network. For each hub gene the Entrez geneid, the official gene symbol and its node degree is given.
Eberhard Korsching (387671) +6 more
core +1 more source
Immunotherapy of osteosarcoma based on immune microenvironment modulation
Frontiers in ImmunologyOsteosarcoma is a highly malignant tumor with unsatisfactory therapeutic outcomes achieved by chemotherapy, radiotherapy, and surgery. As an emerging oncological treatment, immunotherapy has shown potential in the clinical management of many tumors but ...
Heping Lian +8 more
doaj +1 more source
Osteosarcoma in Korean children and adolescents [PDF]
, 2015 Osteosarcoma is the most frequent primary bone tumor. Advances in combination chemotherapy and surgical technique have greatly improved the survival of patients with osteosarcoma.
Jun Ah Lee
core +2 more sources
A temporal coupling hypothesis for chemoresistance in canine DLBCL and osteosarcoma: stress signalling and microRNA regulation. [PDF]
Vet Anim SciAkbari-Ardabili S.
europepmc +2 more sources
Advances in limb salvage treatment of osteosarcoma
, 2018 Osteosarcoma is the most common primary malignant bone tumor; its standard treatment includes neoadjuvant chemotherapy combined with surgery. Neoadjuvant chemotherapy has significantly improved the 5-year survival and limb salvage rates in osteosarcoma ...
Ya Zhang +9 more
core +1 more source
The Anatomical Record, EarlyView.Abstract Studies investigating paleopathologies in sauropods remain scarce despite their relative abundance in the fossil record. In this study we report new occurrence of paleopathological features, corresponding to a neoplasm found in a middle caudal vertebra (MCT.R.2120) of an advanced titanosaur from the Presidente Prudente Formation (Bauru Basin ...
Maria Luiza Peres Bertolossi +5 more
wiley +1 more source
Paediatric development of radiopharmaceutical imaging agents and radioligand therapeutics
British Journal of Clinical Pharmacology, EarlyView.Abstract This review focuses on the development of radiopharmaceutical imaging agents and radioligand therapeutics for paediatric use. Nuclear medicine plays an important role in the diagnosis and treatment of various childhood conditions, including cancers, infections and brain disorders.
Justin L. Hay +5 more
wiley +1 more source
Low-grade osteosarcoma of the ethmoid sinus.
, 2007 Osteosarcoma uncommonly arises in craniofacial bones and has only rarely been reported to arise in the ethmoid sinus. Most primary osteosarcomas arising in paranasal sinuses are high-grade malignancies.
R. Kerr +3 more
core +1 more source