Results 131 to 140 of about 171,941 (345)

S100 A16 promotes the progression of osteosarcoma by activating the PI3 K/AKT signaling pathway through ANXA2

Scientific Reports
Osteosarcoma is a common primary malignant bone tumor. S100A16 gene was reported to highly expressed in several tumor tissues while the relationship between S100A16 and osteosarcoma remains less well-understood.
Ying-Ying Xiang, Jiang-Hua Liu, Xin Yi, Jing-Yao Luo, Yi Yu, Guo-Liang Yi   +5 more
doaj   +1 more source

Cutaneous Leiomyosarcoma of the Head and Neck: Appreciation of a More Indolent Biological Behavior and Implications for Its Management

Head &Neck, EarlyView.
ABSTRACT Background Leiomysosarcoma (LMS) is generally associated with high metastatic potential and poor survival. Cutaneous LMS (cLMS) has been considered a different entity with more indolent biological behavior. Methods A narrative review was performed to assess the biological behavior of cLMS, with special attention for the head and neck location.
Eelco de Bree, Remco de Bree, Carlos Chiesa‐Estomba, Orlando Guntinas‐Lichius, M. P. Sreeram, Dimosthenis Michelakis, Karthik N. Rao, Alessandra Rinaldo, Alfio Ferlito   +8 more
wiley   +1 more source

The many faces of osteosarcoma

, 1997
Osteosarcoma is the most common primary malignant tumor of bone in adolescents and young adults. It accounts for approximately 15% of all primary bone tumors confirmed at biopsy. There are numerous types of primary osteosarcoma, including intramedullary (
Temple, H T, Robbin, M R, Kransdorf, M J, Flemming, D J, Murphey, M D, McRae, G A   +5 more
core   +1 more source

From nature to nanoscale: advances, challenges, and preclinical translation of nanofiber drug delivery systems containing plant‐derived active ingredients

Journal of the Science of Food and Agriculture, EarlyView.
Abstract Since the early 1960s, nanotechnology has been a critical area of science, allowing for the development of sophisticated nanomaterials. Nanofibers, one of the most widely used nanotechnological drug delivery systems, have emerged as a highly versatile platform within modern pharmaceutical sciences.
Heybet Kerem Polat, Yasin Turanlı, Nihat Kurt, Sefa Gözcü, Emre Tunçel, Hilal Bacanak, Eren Aytekin, Sedat Ünal   +7 more
wiley   +1 more source

Comparative spatial transcriptomic profiling of canine and human lung metastatic osteosarcoma tumor microenvironments [PDF]

Daniel P. Regan, Rebecca L. Makii, Kathryn E. Cronise, Michael McKenna, Maria Hernandez, Noémi Kedei, Jennifer Cotter, Troy A. McEachron   +7 more
openalex   +1 more source

Clinical Applications of 3D Specimen Scanning and Margin Mapping in Musculoskeletal Oncology: A 36 Patient Case Series

Journal of Surgical Oncology, EarlyView.
ABSTRACT Background Text‐based pathology reports inadequately communicate complex three‐dimensional (3D) relationships in musculoskeletal oncology, potentially contributing to errors in re‐resection and adjuvant treatment planning. While our prior 7‐case pilot study established technical feasibility, the scalability of this workflow and its utility as ...
Riley S. Gilbertson, Sakshi Krishna, Joaquin Austerlitz, Andreja Radevic, Michael J. Colello, Alexander N. Perez, Reena Singh, Jennifer L. Halpern, Herbert S. Schwartz, Michael C. Topf, Joshua M. Lawrenz, Daniel J. Johnson   +11 more
wiley   +1 more source

Using β-Elemene to reduce stemness and drug resistance in osteosarcoma: A focus on the AKT/FOXO1 signaling pathway and immune modulation

Journal of Bone Oncology
Objective: Osteosarcoma, a highly malignant bone tumor, poses significant treatment challenges due to its propensity for stemness and drug resistance, particularly against doxorubicin (DOX). This study aims to investigate the mechanism by which β-elemene
Shaochun Zhang, Zhijie Xing, Jing Ke
doaj   +1 more source

Osteosarcoma [PDF]

British Journal of Cancer, 2001
Philip, T, Blay, J Y, Brunat-Mentigny, M, Carrie, C, Chauvot, P, Farsi, F, Fervers, B, Gentet, J C, Giammarile, F, Kohler, R, Mathoulin, S, Patricot, L M, Thiesse, P   +12 more
openaire   +2 more sources

Intraoperative Evaluation of Sarcoma Surgical Margins With Indocyanine Green Fluorescence Imaging: Results From an Observational Study

Journal of Surgical Oncology, EarlyView.
ABSTRACT Introduction Sarcomas are rare malignancies that affect both adults and children. Surgical removal with negative histopathological margins is the foundation of sarcoma treatment. Failure to achieve negative margins puts patients at risk of local recurrence (LR). LR rates range between 10% and 30%.
Sumail Bhogal, Matthew Gong, William Li, Brenda Diergaarde, Alma Heyl, Clark Roth, Lawrence Garvin II, Alexander Hoffman, Amanda Locker, Ines Lohse, Maria Silvaggio, Stella Lee, Richard McGough, Kurt Weiss   +13 more
wiley   +1 more source

Downregulation of TMTC4 expression is associated with improved prognosis in osteosarcoma

Journal of International Medical Research
Purpose Osteosarcoma is the most common primary tumor of bone tissue. To date, the expression of transmembrane and tetratricopeptide repeat containing 4 (TMTC4) in osteosarcoma has not been reported.
Zihan Li, Yihao Tian
doaj   +1 more source