Results 141 to 150 of about 171,941 (345)

Integration of single-cell and bulk analysis reveals TBXAS1 as a key platelet-related gene causing poor prognosis in osteosarcoma

open access: yesFrontiers in Genetics
BackgroundPlatelets are associated with poor prognosis in most tumors, but their specific pathogenic mechanism in osteosarcoma is not yet clear. The objective of this study is to conduct an in-depth analysis of how genes closely related to platelet ...
Han Liu   +9 more
doaj   +1 more source

Selective inhibition of MG-63 osteosarcoma cell proliferation induced by curcumin-loaded self-assembled arginine-rich-RGD nanospheres

open access: yes, 2015
Run Chang,1 Linlin Sun,1 Thomas J Webster1,2 1Department of Chemical Engineering, Northeastern University, Boston, MA, USA; 2Center of Excellence for Advanced Materials Research, King Abdulaziz University, Jeddah, Saudi Arabia Abstract: Osteosarcoma is
Sun L, Chang R, Webster TJ
core  

An Analysis of CT‐Guided Percutaneous Core Needle Biopsy of Tibial Lesions: How Successful Are We?

open access: yesJournal of Surgical Oncology, EarlyView.
ABSTRACT Background and Objectives Core needle biopsy (CNB) is commonly used to diagnose bone tumors, but characteristics of tibial lesions may affect its diagnostic performance. We evaluated the diagnostic performance of CT‐guided CNB for tibial lesions, factors associated with diagnostic success, and outcomes of nondiagnostic biopsies.
Lauren E. Wessel   +7 more
wiley   +1 more source

Triptolide Suppresses Tongue Squamous Cell Carcinoma Progression via PI3K–AKT Pathway Inhibition: An Integrative Network Pharmacology and Experimental Validation Study

open access: yesThe Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT Tongue squamous cell carcinoma, the most aggressive subtype of oral squamous cell carcinoma, which is associated with high mortality, frequent recurrence, and early lymph‐node metastasis. Triptolide, a bioactive diterpenoid from Tripterygium wilfordii, exhibits broad anticancer activity.
Shan‐Shan Wang   +3 more
wiley   +1 more source

PATHOMORPHOLOGICAL FEATURES DIAGNOSTIC OF THE OSTEOSARCOMA IN DOGS

open access: yesВетеринарная патология, 2013
Bone tumor are characterized by an aggressive course, early hematogenous metastasis. The incidence of canine osteosarcoma is 80 - 90 % of bone tumors. The main method in diagnosis of osteosarcoma is morphological.
Natalya Viktorovna Mitrokhina   +1 more
doaj  

LncRNA HOXA-AS3 promotes cell proliferation and invasion via targeting miR-218-5p/FOXP1 axis in osteosarcoma

open access: yesScientific Reports
Osteosarcoma is an aggressive form of bone cancer and affects the health in children and adolescents. Although conventional treatment improves the osteosarcoma survival, some patients have metastasis and drug resistance, leading to a worse prognosis ...
Rong Li   +10 more
doaj   +1 more source

Efficacy and safety of ifosfamide-based chemotherapy for osteosarcoma: a meta-analysis

open access: yes, 2015
Xiao-Liang Fan,1,* Guo-Ping Cai,2,* Liu-Long Zhu,1 Guo-Ming Ding1 1Department of Orthopaedics, Hangzhou First People’s Hospital, Nanjing Medical University, Hangzhou, 2Department of Orthopaedics, Jinshan Hospital, Fudan University, Shanghai ...
Cai GP, Zhu LL, Ding GM, Fan XL
core  

Prevention of Early Onset of Breast Cancer With Ashwagandha

open access: yesMolecular Carcinogenesis, EarlyView.
ABSTRACT Prevention of breast cancer is feasible because many risk factors for this malignancy are known (e.g., family history, reproductive factors, etc.). Medicinal plants and/or their bioactive phytochemicals are attractive for the prevention of early onset of breast cancer due to their generally favorable safety profile.
Eun‐Ryeong Hahm   +2 more
wiley   +1 more source

USP14-mediated deubiquitination stabilizes integrin β1 to sustain malignant progression and chemotherapy resistance in osteosarcoma [PDF]

open access: gold
Jiahao Zhang   +14 more
openalex   +1 more source

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