Results 111 to 120 of about 116,442 (313)
Osteosarcoma is the most common primary malignant bone tumor in adolescents. While chemotherapy combined with surgery can improve the prognosis of some patients, chemo-resistance is still a huge obstacle in osteosarcoma treatment.
Zizheng Chen+13 more
doaj
Purpose The function of lncRNAs in cancer stem cells (CSCs) remains to be elucidated. The present study aimed to investigate the regulating role of a novel lncRNA, hypoxia-inducible factor-2α (HIF-2α) promoter upstream transcript (HIF2PUT), in ...
Ding Zhao+3 more
doaj +1 more source
The PCLA‐SNP scaffolds can produce photothermal agents in situ under ultraviolet radiation. Then, the scaffold can release nitric oxide gas spontaneously and generate hyperthermia under near‐infrared laser to enhance ablation of bone tumors. Furthermore, the calcium and iron ions released from PCLA‐SNP scaffolds can accelerate bone regeneration ...
Shaojie Dong+9 more
wiley +1 more source
Cuproplasia and cuproptosis, two sides of the coin
Abstract Copper is an essential micronutrient in the human body, mainly acting as a crucial cofactor required for a wide range of physiological processes across nearly all cell types. Recent advances revealed that tumor cells seize copper to fulfill their rapid proliferation, metastasis, immune evasion, and so on by reprogramming the copper regulatory ...
Kaizhong Lu+4 more
wiley +1 more source
Osteosarcoma in pregnant women is rare. Delay in diagnosis may be due to lack of any signs or symptomsduring gestation, clinical misdiagnoses, religious attitude and refusal of the patients. Most cases soft-tissueand bone tumors during pregnancy can be managed successfully with surgery during gestation.
Sagar Raj Pandey+5 more
openaire +5 more sources
Immunotherapy of osteosarcoma based on immune microenvironment modulation
Osteosarcoma is a highly malignant tumor with unsatisfactory therapeutic outcomes achieved by chemotherapy, radiotherapy, and surgery. As an emerging oncological treatment, immunotherapy has shown potential in the clinical management of many tumors but ...
Heping Lian+8 more
doaj +1 more source
Image based cellular contractile force evaluation with small-world network inspired CNN: SW-UNet [PDF]
We propose an image-based cellular contractile force evaluation method using a machine learning technique. We use a special substrate that exhibits wrinkles when cells grab the substrate and contract, and the wrinkles can be used to visualize the force magnitude and direction.
arxiv
Osteosarcoma of the jaws.Analysis of 56 cases [PDF]
George E. Garrington+3 more
openalex +1 more source
Bioactives From Brown Algae: Antioxidant, Anti‐Inflammatory, Anticancer, and Antimicrobial Potential
This review explores key bioactives in brown algae and their antioxidant, anti‐inflammatory, anticancer, and antimicrobial properties. Covering studies from 2014 to 2024, it highlights their relevance in pharmaceuticals, nutraceuticals, cosmetics, and foods, while addressing challenges and future directions to unlock their full potential.
Irvin Fonseca‐Barahona+2 more
wiley +1 more source
Twenty-Five Years' Experience in the Treatment of Osteosarcoma [PDF]
Carl Krebs
openalex +1 more source