Results 121 to 130 of about 116,442 (313)
ChemBioChem, Accepted Article.Proteoglycans (PGs) play roles in many important biological events including growth factor signaling, wound repair, blood coagulation, brain development, and neural stem cell migration. As the glycosaminoglycan chain of PGs is attached to the core protein through a tetrasaccharide linkage region, it is important to decipher the intricate control of the
Po-han Lin, Xuefei Huang
wiley +1 more source
Molecular Informatics, Volume 42, Issue 1, January 2023., 2023 Abstract Many human diseases including cancer, degenerative and autoimmune disorders, diabetes and others are multifactorial. Pharmaceutical agents acting on a single target do not provide their efficient curation. Multitargeted drugs exhibiting pleiotropic pharmacological effects have certain advantages due to the normalization of the complex ...
O. A. Bocharova +18 more
wiley +1 more source
Bridging Classification and Segmentation in Osteosarcoma Assessment via Foundation and Discrete Diffusion Models [PDF]
arXivOsteosarcoma, the most common primary bone cancer, often requires accurate necrosis assessment from whole slide images (WSIs) for effective treatment planning and prognosis. However, manual assessments are subjective and prone to variability. In response, we introduce FDDM, a novel framework bridging the gap between patch classification and region ...
arxiv
Osteosarcoma Cell and Osteosarcoma Stem Cell Potent Immunogenic Bi‐Nuclear Gallium(III) Complexes
Chemistry – A European Journal, EarlyView.Current treatment options are unable to benefit the majority of osteosarcoma patients with metastasized tumors (70–80% 5‐year fatality rate). Osteosarcoma stem cells (OSCs), a small sub‐population of osteosarcoma cells with stem cell‐like properties, are thought to play a role in the spread of osteosarcoma. In this manuscript, we report the first metal
Xiao Feng +5 more
wiley +1 more source
Pediatric Blood &Cancer, Volume 70, Issue 2, February 2023., 2023 Abstract Background We investigated psychological distress in a South African childhood cancer survivor (CCS) cohort. Methods Adult CCSs treated at Tygerberg Hospital, Cape Town, completed the Brief Symptom Inventory‐18. Internal consistency was acceptable: Cronbach's alpha values were 0.91 (Global Severity Index (GSI)), 0.85 (depression), 0.83 ...
Anel Van Zyl +4 more
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The occurrence of squamous carcinoma and osteosarcoma in young rabbits injected with 90Sr (50-100 mu-c--kg.) [PDF]
, 1965 Samadhan Kshirsagar +2 more
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Journal of Oral and Maxillofacial Pathology, 2012 Tumors of jaw bones are among the most uncommon of all types of neoplasms. Osteosarcoma of jaw bones represents a distinct group of lesions from the conventional type commonly occurring in long bones. Nonetheless, our present knowledge of the tumor allows us to affirm that its clinical behavior and pathologic features differ markedly from those of its ...
Mayur Chaudhary, Shweta Chaudhary
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CleanMat, EarlyView.Biomass Sources, synthesis techniques, structures, applications, and contribution toward SDG goals of biomass‐derived carbon nanomaterials. ABSTRACT Plant life has dominated this planet from the beginning of time. With over 82% of biomass (BM) coming from plants, primarily trees, plants are the dominant form of life on Earth.
A. F. M. Fahad Halim +5 more
wiley +1 more source
Targeting the mitochondrial protein YME1L to inhibit osteosarcoma cell growth in vitro and in vivo
Cell Death and DiseaseExploring novel diagnostic and therapeutic biomarkers is extremely important for osteosarcoma. YME1 Like 1 ATPase (YME1L), locating in the mitochondrial inner membrane, is key in regulating mitochondrial plasticity and metabolic activity.
Xu Sun +5 more
doaj +1 more source