Results 141 to 150 of about 213,774 (293)

A Contemporary Assessment of Osteosarcoma: Lessons from a Comparative Approach

, 2022
Aaron Sarver, Kelly M. Makielski, Jaime F. Modiano   +2 more
openalex   +2 more sources

Paediatric development of radiopharmaceutical imaging agents and radioligand therapeutics

British Journal of Clinical Pharmacology, EarlyView.
Abstract This review focuses on the development of radiopharmaceutical imaging agents and radioligand therapeutics for paediatric use. Nuclear medicine plays an important role in the diagnosis and treatment of various childhood conditions, including cancers, infections and brain disorders.
Justin L. Hay, Amandine Manon, Hunter Stephens, S. Y. Amy Cheung, Bart de Keizer, Erik T. te Beek   +5 more
wiley   +1 more source

Cold atmospheric plasma‐mediated tumor microenvironment remodeling for cancer treatment

BMEMat, EarlyView.
Schematic presentation of CAP‐mediated TME remodeling. This review summarizes recent efforts in cold atmospheric plasma (CAP) application in cancer treatment, highlighting the anticancer potential of CAP, molecular mechanisms, and future perspectives for further improvement and clinical translation.
Israr Khan, Qiujie Fang, Cao Fei, Ziyuan Wang, Zhaowei Chen, Guojun Chen, Zhiming Xu, Shu Xu, Zhitong Chen   +8 more
wiley   +1 more source

PATHOMORPHOLOGICAL FEATURES DIAGNOSTIC OF THE OSTEOSARCOMA IN DOGS

Ветеринарная патология, 2013
Bone tumor are characterized by an aggressive course, early hematogenous metastasis. The incidence of canine osteosarcoma is 80 - 90 % of bone tumors. The main method in diagnosis of osteosarcoma is morphological.
Natalya Viktorovna Mitrokhina, Yuriy Anatolyevich Vatnikov   +1 more
doaj  

Targeting the mitochondrial protein YME1L to inhibit osteosarcoma cell growth in vitro and in vivo

Cell Death and Disease
Exploring novel diagnostic and therapeutic biomarkers is extremely important for osteosarcoma. YME1 Like 1 ATPase (YME1L), locating in the mitochondrial inner membrane, is key in regulating mitochondrial plasticity and metabolic activity.
Xu Sun, Ce Shi, Jin Dai, Mei-Qing Zhang, Dong-Sheng Pei, Lei Yang   +5 more
doaj   +1 more source

Using β-Elemene to reduce stemness and drug resistance in osteosarcoma: A focus on the AKT/FOXO1 signaling pathway and immune modulation

Journal of Bone Oncology
Objective: Osteosarcoma, a highly malignant bone tumor, poses significant treatment challenges due to its propensity for stemness and drug resistance, particularly against doxorubicin (DOX). This study aims to investigate the mechanism by which β-elemene
Shaochun Zhang, Zhijie Xing, Jing Ke
doaj   +1 more source

<p>Piceatannol Suppresses the Proliferation and Induced Apoptosis of Osteosarcoma Cells Through PI3K/AKT/mTOR Pathway</p>

, 2020
Bin Wang, Jingyu Li
openalex   +2 more sources

Nanomaterials‐mediated glycolysis rewriting to potentiate tumor immunotherapy

BMEMat, EarlyView.
This review systematically summarizes cutting‐edge advances in glycolysis‐rewiring nanomedicines, emphasizing their mechanisms in reversing immunosuppression and reinvigorating antitumor immune responses. Challenges in clinical translation and future directions for designing multifunctional metabolic‐immune modulators are also critically discussed ...
Zilin Ma, Songyan Li, Jie Yan, Xuechun Wang, Wen Zhao, Yunxuan Song, Dongdong Liu, Jianwei Jiao, Xiuying Duan, Guiqiang Zhang   +9 more
wiley   +1 more source

Integration of single-cell and bulk analysis reveals TBXAS1 as a key platelet-related gene causing poor prognosis in osteosarcoma

Frontiers in Genetics
BackgroundPlatelets are associated with poor prognosis in most tumors, but their specific pathogenic mechanism in osteosarcoma is not yet clear. The objective of this study is to conduct an in-depth analysis of how genes closely related to platelet ...
Han Liu, Wacili Da, Jianhua Mu, Xuanhong He, Zhuangzhuang Li, Taojun Gong, Jingjing Wang, Li Min, Minxun Lu, Chongqi Tu   +9 more
doaj   +1 more source

Pelvic Osteosarcoma: Resection and Reconstruction Using a Customised Plate [PDF]

, 2021
Zeineb Alaya, Mohamed Ali Khalifa, Lassaad Hassini, Mehdi Jedidi, Adnen Siala, Walid Osman, Karim Bouattour   +6 more
openalex   +1 more source