Results 31 to 40 of about 116,442 (313)

ROCK2 Regulates Invasion and Migration of Osteosarcoma Cells

open access: yesZhongliu Fangzhi Yanjiu, 2022
Objective To analyze the expression of ROCK2 in osteosarcoma tissues and explore its effect on the invasion and migration of osteosarcoma cells and related mechanism.
SHAN Wenhao   +4 more
doaj   +1 more source

Osteosarcoma and Metastasis [PDF]

open access: yesFrontiers in Oncology, 2021
Osteosarcoma is the most common primary bone malignancy in adolescents. Its high propensity to metastasize is the leading cause for treatment failure and poor prognosis. Although the research of osteosarcoma has greatly expanded in the past decades, the knowledge and new therapy strategies targeting metastatic progression remain sparse.
Gaohong Sheng   +3 more
openaire   +3 more sources

LncRNA EBLN3P attributes methotrexate resistance in osteosarcoma cells through miR-200a-3p/O-GlcNAc transferase pathway

open access: yesJournal of Orthopaedic Surgery and Research, 2022
Background Osteosarcoma is highly malignant. The migration, invasion, and chemoresistance contribute to poor prognosis of osteosarcoma. Research reported that endogenous bornavirus-like nucleoprotein 3 pseudogene (EBLN3P) promotes the progression of ...
Ming-Xia Sun   +4 more
doaj   +1 more source

Exosomes and their roles in the chemoresistance of pancreatic cancer

open access: yesCancer Medicine, Volume 11, Issue 24, Page 4979-4988, December 2022., 2022
Despite the development of multiple promising chemotherapeutic agents as recommended first‐line treatment for PC, the therapeutic efficacy is largely limited by unwanted drug resistance.Exploring the relation between exosomes and chemoresistance may be conducive to understanding molecular mechanisms and taking effective measures to reduce the ...
Yubin Pan   +4 more
wiley   +1 more source

Noise-reducing attention cross fusion learning transformer for histological image classification of osteosarcoma [PDF]

open access: yesarXiv, 2022
The degree of malignancy of osteosarcoma and its tendency to metastasize/spread mainly depend on the pathological grade (determined by observing the morphology of the tumor under a microscope). The purpose of this study is to use artificial intelligence to classify osteosarcoma histological images and to assess tumor survival and necrosis, which will ...
arxiv  

Deep Interactive Learning: An Efficient Labeling Approach for Deep Learning-Based Osteosarcoma Treatment Response Assessment [PDF]

open access: yes, 2020
Osteosarcoma is the most common malignant primary bone tumor. Standard treatment includes pre-operative chemotherapy followed by surgical resection. The response to treatment as measured by ratio of necrotic tumor area to overall tumor area is a known prognostic factor for overall survival.
arxiv   +1 more source

Cellular functions and molecular mechanisms of ubiquitination in osteosarcoma

open access: yesFrontiers in Oncology, 2022
Although some advances have been made in the treatment of osteosarcoma in recent years, surgical resection remains the mainstream treatment. Initial and early diagnosis of osteosarcoma could be very difficult to achieve due to the insufficient ...
Jiaxun Song   +8 more
doaj   +1 more source

Osteosarcoma of the maxilla

open access: yesJournal of the Belgian Society of Radiology, 2012
Background: A 25-year-old male patient presented with tooth pain and progressive swelling of his left cheek. Dental examination was unremarkable.
Vanhoenacker, Filip   +3 more
openaire   +8 more sources

Osteosarcomas of the Heart [PDF]

open access: yesThe American Journal of Surgical Pathology, 1991
We reviewed nine primary cardiac sarcomas with osteosarcomatous differentiation. The patients' ages ranged from 24 to 67 (mean 38 years). All tumors were surgical specimens from the left atrium; many were clinically diagnosed as atypical myxomas. In eight cases complete excisions were attempted, one requiring reconstruction with grafting; one tumor was
Burke, Allen P., Virmani, Renu
openaire   +4 more sources

Molecular and cellular paradigms of multidrug resistance in cancer

open access: yesCancer Reports, Volume 5, Issue 12, December 2022., 2022
Abstract Background The acquisition of resistance to chemotherapy is a major hurdle in the successful application of cancer therapy. Several anticancer approaches, including chemotherapies, radiotherapy, surgery and targeted therapies are being employed for the treatment of cancer.
Foram U. Vaidya   +6 more
wiley   +1 more source

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