Results 41 to 50 of about 241,082 (329)

Maxillary osteosarcoma in a beef suckler cow [PDF]

open access: yes, 2012
A ten-year-old beef suckler cow was referred to the Scottish Centre for Production Animal Health and Food Safety of the University of Glasgow, because of facial swelling in the region of the right maxilla.
Barrett, D.C., Prins, D.G.J., Wittek, T.
core   +3 more sources

Identification and Verification of Immune-Related Gene Prognostic Signature Based on ssGSEA for Osteosarcoma

open access: yesFrontiers in Oncology, 2020
Osteosarcoma is the most common malignant bone tumor in children and adolescence. Multiple immune-related genes have been reported in different cancers.
Bo Xiao   +6 more
semanticscholar   +1 more source

Ferroptosis‐related gene signature associates with immunity and predicts prognosis accurately in patients with osteosarcoma

open access: yesCancer Science, 2021
Osteosarcoma has been the most common malignant bone tumor in children and adolescents, while the 5‐y survival of osteosarcoma patients gained no significant improvement over the past decades.
Ting Lei, Hu Qian, Pengfei Lei, Yihe Hu
semanticscholar   +1 more source

Clinical Features and Outcomes Differ between Skeletal and Extraskeletal Osteosarcoma. [PDF]

open access: yes, 2014
Background. Extraskeletal osteosarcoma (ESOS) is a rare subtype of osteosarcoma. We investigated patient characteristics, overall survival, and prognostic factors in ESOS. Methods.
Boscardin, W John   +4 more
core   +2 more sources

Clinical Trials of Immunogene Therapy for Spontaneous Tumors in Companion Animals [PDF]

open access: yes, 2014
Despite the important progress obtained in the treatment of some pets’ malignancies, new treatments need to be developed. Being critical in cancer control and progression, the immune system’s appropriate modulation may provide effective therapeutic ...
Finocchiaro, Liliana Maria Elena   +1 more
core   +9 more sources

Pathogenesis and Current Treatment of Osteosarcoma: Perspectives for Future Therapies

open access: yesJournal of Clinical Medicine, 2021
Osteosarcoma is the most common primary malignant bone tumor in children and young adults. The standard-of-care curative treatment for osteosarcoma utilizes doxorubicin, cisplatin, and high-dose methotrexate, a standard that has not changed in more than ...
R. Rathore, B. V. Van Tine
semanticscholar   +1 more source

The subcellular distribution of phosphorylated Y‐box‐binding protein‐1 at S102 in colorectal cancer patients, stratified by KRAS mutational status and clinicopathological features

open access: yesMolecular Oncology, EarlyView.
This study identifies nuclear YB‐1 S102 phosphorylation as a marker associated with KRAS and FBXW7 mutations in colorectal cancer. Mutated KRAS correlates specifically with nuclear, not cytoplasmic, S102 YB‐1. These findings provide the first ex vivo evidence of this link in CRC and suggest future studies should assess the prognostic and therapeutic ...
Konstanze Lettau   +9 more
wiley   +1 more source

Telangiectatic Osteosarcoma [PDF]

open access: yesJournal of Orthopaedic Surgery, 2013
Purpose. To review records of 8 patients with telangiectatic osteosarcoma (TOS) and determine whether pathologic fractures correlate with recurrence and survival. Methods. Records of 4 men and 4 women aged 17 to 44 (mean, 28) years treated for TOS were reviewed. Results. Of the 8 patients, 4 developed a pathologic fracture and 4 did not. In each group,
Jordi Colomina   +3 more
openaire   +4 more sources

Detection of circulating tumour DNA is associated with inferior outcomes in Ewing sarcoma and osteosarcoma: a report from the Children's Oncology Group. [PDF]

open access: yes, 2018
BackgroundNew prognostic markers are needed to identify patients with Ewing sarcoma (EWS) and osteosarcoma unlikely to benefit from standard therapy.
Barkauskas, Donald A   +20 more
core   +1 more source

BMP antagonist CHRDL2 enhances the cancer stem‐cell phenotype and increases chemotherapy resistance in colorectal cancer

open access: yesMolecular Oncology, EarlyView.
Overexpression of CHRDL2 in colon cancer cells makes them more stem‐like and resistant to chemo‐ and radiotherapy. CHRDL2‐high cells have upregulation of the WNT pathway, genes involved in the DNA damage response (DDR) pathway and epithelial‐to‐mesenchymal transition (EMT). This leads to quicker repair of damaged DNA and more cell migration.
Eloise Clarkson, Annabelle Lewis
wiley   +1 more source

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