Results 71 to 80 of about 116,442 (313)

Single-shot multispectral quantitative phase imaging using deep neural network [PDF]

arXiv, 2022
Multi-spectral quantitative phase imaging (MS-QPI) is a cutting-edge label-free technique to determine the morphological changes, refractive index variations and spectroscopic information of the specimens. The bottleneck to implement this technique to extract quantitative information, is the need of more than two measurements for generating MS-QPI ...
arxiv  

A UV-cured nanofibrous membrane of vinylbenzylated gelatin-poly(ε-caprolactone) dimethacrylate co-network by scalable free surface electrospinning [PDF]

Materials Science and Engineering: C Mater. Sci. Eng. C 2018 (91) 541-555, 2018
Electrospun nanofibrous membranes of natural polymers, such as gelatin, are fundamental in the design of regenerative devices. Crosslinking of electrospun fibres from gelatin is required to prevent dissolution in water, to retain the original nanofibre morphology after immersion in water, and to improve the thermal and mechanical properties, although ...
arxiv   +1 more source

Probiotic‐Based Mineralized Living Materials to Produce Antimicrobial Yogurts

Advanced Healthcare Materials, EarlyView.
The self‐assembly and mineralization of collagen in the presence of probiotics produces hybrid living materials that hosts and protects the cells. Intra‐ and interfibrillar mineralization of collagen fibers, as occurring in bone, results, respectively, in a bulk and single‐cell protective layer of cells, that survive in simulated gastric conditions and,
Gloria B. Ramírez‐Rodríguez, Laura Sabio, Laura Cerezo‐Collado, Víctor Garcés, Jose M. Domínguez‐Vera, José M. Delgado‐López   +5 more
wiley   +1 more source

In vitro cytocompatibility and antibacterial studies on biodegradable Zn alloys supplemented by a critical assessment of direct contact cytotoxicity assay

Journal of Biomedical Materials Research Part B: Applied Biomaterials, Volume 111, Issue 2, Page 241-260, February 2023., 2023
Abstract In vitro cytotoxicity assessment is indispensable in developing new biodegradable implant materials. Zn, which demonstrates an ideal corrosion rate between Mg‐ and Fe‐based alloys, has been reported to have excellent in vivo biocompatibility.
Maria Wątroba, Wiktor Bednarczyk, Piotr K. Szewczyk, Jakub Kawałko, Krzysztof Mech, Alina Grünewald, Irem Unalan, Nicola Taccardi, Gabriela Boelter, Manuel Banzhaf, Caroline Hain, Piotr Bała, Aldo R. Boccaccini   +12 more
wiley   +1 more source

Recent Applications of Mesoporous Silica Nanoparticles in Gene Therapy

Advanced Healthcare Materials, EarlyView.
The review summarizes the synthesis of mesoporous silica nanoparticles (MSNs) with modifiable surface properties, functionalization strategies, mechanism of therapeutic payload release, and current applications in gene therapy, focusing on their capabilities in the targeted delivery of therapeutic nucleic acids, CRISPR‐Cas systems, and other genetic ...
Tamanna Binte Huq, Punnya Anil Kumar Jeeja, Sudip Kumar Dam, Sabya Sachi Das, Juan L. Vivero‐Escoto   +4 more
wiley   +1 more source

Solvent types used for the preparation of hydrogels determine their mechanical properties and influence cell viability through gelatine and calcium ions release

Journal of Biomedical Materials Research Part B: Applied Biomaterials, Volume 111, Issue 2, Page 314-330, February 2023., 2023
By the selection of the hydrogel composition, applied solvents, and concentration of the cross‐linking compound, it is possible to modify the properties of the materials designated for bioinks for 3D printing in Bone Tissue Engineering. Abstract Alginate‐gelatin hydrogels are the most commonly used materials for 3D bioprinting.
Karolina Rosińska, Mateusz Bartniak, Adrianna Wierzbicka, Anna Sobczyk‐Guzenda, Dorota Bociaga   +4 more
wiley   +1 more source

Long noncoding RNA OR3A4 promotes the proliferation and invasion of osteosarcoma cells by sponging miR-1227-5p

Journal of Bone Oncology, 2020
Background: Long noncoding RNAs (lncRNAs) have been identified as key players in promoting tumourigenesis in osteosarcoma. LncRNA OR3A4 (OR3A4) has been reported as an oncogene in a number of tumours.
Changcheng Yang, Xingrui Cai, Mengsi Yu, Bangmin Wang, Song Wang, Zhihui He, Jiangzheng Zeng, Boke Zhang, Yanda Lu   +8 more
doaj  

Triptolide inhibits the growth of osteosarcoma by regulating microRNA-181a via targeting PTEN gene in vivo and vitro

Tumor Biology, 2017
We aimed to study the anti-tumor effects of triptolide on osteosarcoma and the related molecular mechanisms. The cell viability, apoptosis portion, tumor size, tumor weight, and invasion of osteosarcoma cells were determined.
Chunming Jiang, Xiang Fang, Hongxu Zhang, Xuepeng Wang, Maoqiang Li, Wu Jiang, Fei Tian, Liulong Zhu, Zhenyu Bian   +8 more
doaj   +1 more source

ITGB3 promotes cisplatin resistance in osteosarcoma tumors

Cancer Medicine, 2023
Objective Osteosarcoma is the most malignant and common primary bone tumor with a high rate of recurrence that mainly occurs in children and young adults.
Qian Li, Guangyou Chen, Huachai Jiang, Haoping Dai, Dongdong Li, Kai Zhu, Kaiquan Zhang, Huarui Shen, Houping Xu, Sen Li   +9 more
doaj   +1 more source

FGF2 Mediated USP42‐PPARγ Axis Activation Ameliorates Liver Oxidative Damage and Promotes Regeneration

Advanced Science, EarlyView.
USP42 is identified as a novel DUB of PPARγ in hepatocytes. USP42 mediated PPARγ deubiquitylation determines its transcriptional preference on proliferative and redox balance genes. USP42 knockdown exacerbates liver damage and delays regeneration. FGF2 is the upstream signal that initiates and activates the USP42‐PPARγ axis.
Nanfei Yang, Qiang Tian, Zhenli Lei, Shuxin Wang, Nan Cheng, Zhen Wang, Xianqin Jiang, Xuqun Zheng, Wenjing Xu, Minyan Ye, Longwei Zhao, Meiyun Wen, Jianlou Niu, Weijian Sun, Pingping Shen, Zhifeng Huang, Xiaokun Li   +16 more
wiley   +1 more source