Results 171 to 180 of about 1,561,508 (282)

Assessing the Role of Cardiac Disease in Severe Maternal Morbidity: A Population-Based Cohort Study. [PDF]

O G Open
Darmawan KF, Sherwin EB, Leonard SA, Panelli DM, Mayo JA, Girsen AI, Carmichael SL, Khandelwal A, Bianco K.   +8 more
europepmc   +1 more source

Proteasomal degradation of intracellularly expressed Amblyomin‐X limits suicide gene therapy potential in melanoma cells

FEBS Open Bio, EarlyView.
This study explores the feasibility of expressing the antitumoral protein Amblyomin‐X through a suicide gene therapy approach and investigates its intracellular fate after gene delivery. Although the gene is efficiently expressed, melanoma cells rapidly degrade the Amblyomin‐X protein via proteasome activity.
Victor Dal Posolo Cinel, Carlos DeOcesano Pereira, Aline Ramos Maia Lobba, Melissa Regina Fessel, Ana Marisa Chudzinski‐Tavassi   +4 more
wiley   +1 more source

Success rates of American clinical oncology trials by geographic factors. [PDF]

Sci Rep
Patiyal S, Schäffer AA.
europepmc   +1 more source

Rapid screening of staphylokinase protein variants using an unpurified cell‐free expression system

FEBS Open Bio, EarlyView.
An unpurified cell‐free protein synthesis (CFPS) platform enables rapid functional screening of staphylokinase variants. Direct plasminogen‐activation assays performed in microplate format provide real‐time activity readouts, allowing rapid identification and ranking of variants with improved or reduced fibrinolytic activity without protein ...
Maria Tomková, Veronika Hovanová, Jiri Damborsky, Erik Sedlák   +3 more
wiley   +1 more source

DIFFERENTIATION OF PART-TIME JOB AND COMBINATION OF DUTIES FROM OTHER TYPES OF ACTIVITIES IN THE OFFENSE UNDER ARTICLE 1724 OF THE CODE OF UKRAINE ON ADMINISTRATIVE OFFENSES (CUAO)

Право.ua, 2020
openaire   +1 more source

Eating Experiences of Patients With Cancer in the Hospital - A Qualitative Study. [PDF]

J Hum Nutr Diet
van Elst JM, Beukers K, Beijer S, Janssen-Heijnen M, Reyners AKL, Jager-Wittenaar H, de Haan JJ.   +6 more
europepmc   +1 more source

Evolutionarily divergent DUF4465 domains have a common vitamin B12‐binding function

FEBS Open Bio, EarlyView.
We show that DUF4465 family proteins, widespread across bacteria from gut microbiomes, hydrothermal vents, and soil, share a common vitamin B12‐binding function. These augmented β‐jellyroll proteins bind vitamin B12 via extended loops. Our findings establish sequence‐diverse DUF4465 proteins as a widespread class of B12‐binding proteins, highlighting ...
Charlea Clarke, Michal Banasik, Rokas Juodeikis, Martin J. Warren, Richard W. Pickersgill   +4 more
wiley   +1 more source

Computing double-pushout graph transformation rules and atom-to-atom maps from KEGG RCLASS data. [PDF]

Algorithms Mol Biol
Beier N, Gatter T, Andersen JL, Stadler PF.   +3 more
europepmc   +1 more source

Systemic dysregulation of apolipoproteins in amyotrophic lateral sclerosis serum

FEBS Open Bio, EarlyView.
Amyotrophic lateral sclerosis (ALS) is a fatal disease that damages motor neurons. This study found that people with ALS show significant changes in blood fats and the proteins that carry them. Several apolipoproteins were higher, lipid balances were altered, and normal protein–lipid relationships were disrupted.
Finula I. Isik, Russell Pickford, Hannah C. Timmins, Olivier Piguet, Glenda M. Halliday, Matthew C. Kiernan, Woojin Scott Kim   +6 more
wiley   +1 more source

Quick response codes in the breakfast cereal aisle: prevalence, landing page, and product characteristics. [PDF]

Health Promot Int
Bathie L, Chen MCL, Leahy A, Sträuli B, Pettigrew S, Barrett EM.   +5 more
europepmc   +1 more source