Results 101 to 110 of about 24,961 (203)

Ototoxicity: a high risk to auditory function that needs to be monitored in drug development

Frontiers in Molecular Neuroscience
Hearing loss constitutes a major global health concern impacting approximately 1.5 billion people worldwide. Its incidence is undergoing a substantial surge with some projecting that by 2050, a quarter of the global population will experience varying ...
Marie-Pierre Pasdelou, Lise Byelyayeva, Susanna Malmström, Sylvie Pucheu, Marie Peytavy, Hugo Laullier, Donald B. Hodges, Abraham R. Tzafriri, Gaëlle Naert   +8 more
doaj   +1 more source

Early Detection of Ototoxicity Using Serial Mobile Audiometry, Otoacoustic Emissions Testing, and Inner Ear Biomarker Measurement in Patients Receiving Platinum-Based Chemotherapy Treatment: It is Feasible to Implement in a National Health Service (NHS) Cancer Ambulatory Care Setting. [PDF]

Otol Neurotol
Mehta N, Awad A, Forbes M, Iliadou E, Katiri R, Ferdous T, Lowe H, Ensell L, Alifrangis C, Schilder AGM, Windsor R.   +10 more
europepmc   +1 more source

Identifying Gaps and Opportunities to Improve Ototoxicity Management in Veterans With Cancer: Evidence From a Retrospective Cohort and Oncology Provider Survey. [PDF]

Cancer Med
Lacey C, Clark K, Debacker JR, Stuehm H, Hungerford M, Milnes T, Johansson K, Mannino R, Graff JN, Konrad-Martin D.   +9 more
europepmc   +1 more source

In Silico Hazard Assessment of Ototoxicants Through Machine Learning and Computational Systems Biology. [PDF]

Toxics
Luan S, Ji C, Zarus GM, Reh CM, Ruiz P.
europepmc   +1 more source

Liposome-Encapsulated Rutin Attenuates Cisplatin-Induced Ototoxicity via Suppression of P53-Associated Oxidative Injury. [PDF]

Biomater Res
Liu B, Tu Y, Li X, Yu W, Zou W, Tang W, Zong S, Tan S, Xiao H.   +8 more
europepmc   +1 more source

Monitoring Ototoxicity in Cancer Patients Undergoing Platinum-Based Chemotherapy and Radiation in Saudi Arabia: Challenges and Solutions. [PDF]

J Multidiscip Healthc
AlJasser A.
europepmc   +1 more source

Baicalin attenuates cisplatin-induced cochlear hair cell damage by modulating the ROS-p38 MAPK signaling pathway. [PDF]

Front Cell Dev Biol
Zhang Q, Wang Y, Zhang C, Li S, Yin Q, Zhou C, Dong C, Bu C.   +7 more
europepmc   +1 more source

Eleutheroside E alleviates cisplatin-induced ototoxicity by down-regulating MAPK/NF-κB/NLRP3 signaling pathway and inhibiting cochlear cell pyroptosis. [PDF]

Commun Biol
Zhang Y, Lu L, Tong B, Wang J, Liu K, Zhang J, Zhang D, Tian M, Sun W, Liu H, Wang P, Duan M, Tang Y.   +12 more
europepmc   +1 more source

Bortezomib-Induced Sensorineural Hearing Loss May Be Reversible with Intratympanic Dexamethasone. [PDF]

Hematol Rep
Peláez Casillas N, Verdaguer Muñoz JM, Rodríguez Valiente A, Romera Martínez I, García Berrocal JR.   +4 more
europepmc   +1 more source

Experimental and Clinical Approaches to Preventing Aminoglycoside-Induced Ototoxicity: A Scoping Review. [PDF]

Antioxidants (Basel)
Zadrożniak M, Biskupski M, Szymański M, Łuszczki JJ.   +3 more
europepmc   +1 more source