Results 81 to 90 of about 25,486 (236)

The Role of Anatomy‐Based Fitting in Bimodal Rehabilitation: Choosing Electrode Arrays Based on Cochlear Length

World Journal of Otorhinolaryngology - Head and Neck Surgery, EarlyView.
ABSTRACT Objectives To evaluate the clinical impact of anatomy‐based fitting (ABF) in cochlear implants for patients with asymmetric hearing loss. Study Design Prospective cohort study. Setting Tertiary referral center specializing in hearing disorders.
Andrea Canale, Arianna Daquino, Maria Gragnano, Claudia Filippini, Marco Boldreghini, Giuseppe Riva, Andrea Albera   +6 more
wiley   +1 more source

An Ototoxicity Grading System Within a Mobile App (OtoCalc) for a Resource-Limited Setting to Guide Grading and Management of Drug-Induced Hearing Loss in Patients With Drug-Resistant Tuberculosis: Prospective, Cross-Sectional Case Series

JMIR mHealth and uHealth, 2020
BackgroundTuberculosis (TB) affects millions of people worldwide and is treated with medication including aminoglycosides and polypeptides. Individuals respond differently to medications as a result of their genetic inheritance.
Hollander, Cara, Joubert, Karin, Schellack, Natalie   +2 more
doaj   +1 more source

Intravesical therapy for recurrent urinary tract infection: a systematic review and meta‐analysis

BJU International, EarlyView.
Objective To undertake a systematic review and meta‐analysis to evaluate the efficacy, safety, and clinical applicability of intravesical instillations for preventing recurrent urinary tract infections (rUTIs). Methods PubMed/MEDLINE, Embase, Cochrane CENTRAL, Scopus, and Web of Science were searched from January 2000 to April 2025 for randomised and ...
Matthew Kwon, Asaad Ahmad, Natalie Lott, Alison Blatt   +3 more
wiley   +1 more source

Efficacy of three drugs for protecting against gentamicin-induced hair cell and hearing losses [PDF]

, 2012
BACKGROUND AND PURPOSEExposure to an ototoxic level of an aminoglycoside can result in hearing loss. In this we study investigated the otoprotective efficacy of dexamethasone (DXM), melatonin (MLT) and tacrolimus (TCR) in gentamicin (GM)-treated animals ...
Bas, E, Dinh, J, Gupta, C, Láinez Andrés, José Miguel, Marco, J, Martínez-Soriano, F, Van De Water, TR, Vu, L   +7 more
core   +1 more source

Relationship Between Serum Ferritin Level and Amikacin Ototoxicity

Oman Medical Journal, 2012
Objectives: Aminoglycosides are highly effective against bacteria but have serious side-effects including ototoxicity and nephrotoxicity. One of the theories in aminoglycosides ototoxicity is that Iron-aminoglycoside complex causes ototoxicity by ...
Mohammad Shayaninasab, Mohammadreza Fatololoomi, Fatollah Behnood, Azam Alizamir   +3 more
doaj  

Intermediate filaments link glutamate–aspartate transporter deficiency to cochlear synaptopathy

The FEBS Journal, EarlyView.
In a healthy ear, GLAST transporters in supporting cells clear excess glutamate to protect auditory connections. When GLAST is missing, glutamate accumulates and leads to the destruction of structural scaffolding within the postsynaptic nerve endings. This internal collapse causes a loss of synapses that are essential for hearing, ultimately resulting ...
Paul Emmerich Krumpoeck, Lukas David Landegger   +1 more
wiley   +1 more source

Evaluation of a New, Community‐Based Screening Program to Detect Hearing Loss in Adult Childhood Cancer Survivors in Switzerland: Findings From the HEAR Study

Pediatric Blood &Cancer, Volume 73, Issue 6, June 2026.
ABSTRACT Background Childhood cancer survivors (CCS) have an increased risk of long‐term health complications, including treatment‐related hearing loss. Although early detection is important, many adult survivors do not attend hearing screenings in clinical centers because visits can be logistically or emotionally burdensome.
Philippa Jörger, Carina Nigg, Christina Schindera, Maša Žarković, Grit Sommer, Martin Kompis, Annika Frahsa, Nicolas Waespe, Marc Ansari, Claudia E. Kuehni   +9 more
wiley   +1 more source

Otoprotective properties of 6α-methylprednisolone-loaded nanoparticles against cisplatin: In vitro and in vivo correlation [PDF]

, 2016
This is the peer reviewed version of the following article: Nanomedicine: Nanotechnology, Biology and Medicine (2016): 59-65, which has been published in final form at http://dx.doi.org/10.1016/j.nano.2015.12.3676α-Methylprednisolone-loaded surfactant ...
Aguilar, María Rosa, Martín-Saldaña, Sergio, Palao-Suay, Raquel, Ramírez-Camacho, Rafael, San Román, Julio, Trinidad, Almudena   +5 more
core   +2 more sources

PACS2 Alleviates Sepsis‐Induced Myopathy by Activating ERK–MAPK Signalling Pathway to Suppress ER‐Phagy

Journal of Cachexia, Sarcopenia and Muscle, Volume 17, Issue 3, June 2026.
ABSTRACT Background Sepsis‐induced myopathy (SIM) is a common and life‐threatening complication, but its underlying mechanisms remain poorly understood. PACS2, a key resident protein at mitochondria‐associated endoplasmic reticulum membranes (MAMs), regulates ER homeostasis under various pathological conditions.
Xuexin Li, Zu‐an Shi, Fei He, Guo Mu, Feixiang Wang, Bowen Sun, Xiaobin Wang, Li Liu   +7 more
wiley   +1 more source

Systemic aminoglycosides-induced vestibulotoxicity in humans

, 2017
Objectives: This systematic review aimed to investigate the prevalence and characteristics of vestibular adverse effects of aminoglycoside (AG) therapy in humans and to analyze objective vestibular tests for the detection of AG-induced vestibulotoxicity.
Agrawal, Ahmed, Ahmed, Ahmed, Al-Malky, Ariano, Aust, Barza, Black, Black, Black, Caminero, Carey, Chen, Chiodo, Colebatch, Curthoys, Davis, Deka, Demer, Dobie, Elfving, Esterhai, Eviatar, Farzal, Fausti, Fee, Finitzo-Hieber, Forge, Fujimoto, Gendeh, Gendeh, Geyer, Gibson, Goldberg, Gonçalves, Govaerts, Grohskopf, Guinand, Hain, Halmagyi, Halmagyi, Hauch, Hermann, Hinshaw, Huizing, Ishiyama, Ishiyama, Kahlmeter, Kim, Landis, Lehmann, Leis, Lerner, Li, Liberati, Lindeman, Liu, Lucieer, Lue, Lyford-Pike, Maes, Maes, Matz, McCaslin, Mendel, Minor, Nakashima, Noone, Pedersen, Petersen, Pillers, Poirrier, Prayle, Price, Rizzi, Rogers, Rosengren, Rybak, Schacht, Schatz, Scheenstra, Selimoglu, Selimoğlu, Stavroulaki, Stevenson, Sun, Sun, Tange, Thomas, Tjernström, Tjernström, Tsuji, van de Berg, Vasquez, Venhovens, Ward, Weber, Winkel, Wuyts, Wuyts, Zagólski, Zingler   +102 more
core   +1 more source