Results 81 to 90 of about 19,052 (152)

Clinical Predictors of Cisplatin Chemoradiation-Induced Ototoxicity in HPV-Positive Oropharyngeal Squamous Cell Carcinoma: A Case-Control Study

Journal of Otolaryngology - Head and Neck Surgery
Background Cisplatin-based chemoradiation is a standard treatment for many patients with human papillomavirus (HPV)-positive oropharyngeal squamous cell carcinoma (OPSCC), an etiologically distinct subset of head and neck cancer. Although associated with
John JW. Lee MD, Salahaldin Alamleh BHSc, Luna Jia Zhan MPH, Katrina Hueniken MSc, Mary B. Mahler MD, Astrid Billfalk-Kelly MD, Joel Davies MD, M. Catherine Brown MSc, Anna Spreafico MD, Shao Hui Huang MSc, Andrew Hope MD, Wei Xu PhD, David P. Goldstein MD, Geoffrey Liu MD   +13 more
doaj   +1 more source

Ototoxic drugs, diagnosis and monitoring

, 2019
Ototoxicity is a cochlear or vestibular dysfunction caused by chemical, physical or biological effects. It affects the internal ear and hearing nerve and might be reversible or irreversible.
Tan M., Toplu Y.
core   +1 more source

J Toxicol Environ Health B Crit Rev [PDF]

To determine the state of the research on ototoxic properties of Pb, evaluate possible synergistic effects with concurrent noise exposure, and identify opportunities to improve future research, we performed a review of the peer-reviewed literature to ...

core  

Standardizing ototoxicity monitoring for children treated with cisplatin: an urgent call to action

Frontiers in Oncology
Over the past 25 years, considerable progress has been made in identifying the prevalence, risk factors, functional impacts, and protective strategies for cisplatin-induced ototoxicity.
Kristin Knight, Milanka Drenovak, Thorsten Langer, Nienke Streefkerk, Tri Juda Airlangga, Murti Andriastuti, Asmarinah, Deborah Berndtson, Adwina Nurlita Kusuma Wardhani Hartantyo, Alexander E. Hoetink, Alexander E. Hoetink, Kim E. de Jager, Dawn Konrad Martin, Dawn Konrad Martin, Cimi Ilmiawati, M. Tayyar Kalcioglu, Ika Dewi Mayangsari, Nyilo Purnami, Shally Adhina Putri, Haldun Oguz, Irene Schmid, Rasjid Soeparwata, Helen Spoudeas, Anna-Katharina Rohlfs, Kaukab Rajput, Penelope Brock, Marry M. van den Heuvel-Eibrink, Antoinette am Zehnhoff-Dinnesen   +27 more
doaj   +1 more source

Role of RGS17 in cisplatin-induced cochlear inflammation and ototoxicity via caspase-3 activation

Frontiers in Immunology
Cisplatin is a chemotherapy drug used to treat different solid tumors, including ovarian, bladder, lung, and head and neck cancers. One of its significant side effects is ototoxicity, especially when high doses are required. Cisplatin-induced ototoxicity
Raheem F. H. Al Aameri, Raheem F. H. Al Aameri, Entkhab M. A. Alanisi, Dheyaa Al Sallami, Ian Alberts, Shelley Tischkau, Leonard P. Rybak, Vickram Ramkumar   +7 more
doaj   +1 more source

Mechanistic insights into cisplatin-induced ototoxicity: the central role of transient receptor potential channels

Frontiers in Molecular Biosciences
This review systematically elucidates the molecular mechanisms underlying cisplatin-induced ototoxicity, with a particular focus on the pivotal role played by TRP channels.
Man Yu, Man Yu, Juanjuan Li, Xianhai Zeng, Xianhai Zeng   +4 more
doaj   +1 more source

Demographic data of patients with ototoxicity included for meta-analysis.

, 2014
Demographic data of patients with ototoxicity included for meta-analysis.
Eveline S. J. M. de Bont (87571), Ana Patino-Garcia (5661973), Maroeska W. M. te Loo (680904), Melanie M. Hagleitner (680902), Marieke J. H. Coenen (176218), Henk-Jan Guchelaar (78210), Frank N. van Leeuwen (88846), Anna Gonzalez-Neira (81748), Hanneke I. Vos (680903), Peter M. Hoogerbrugge (184736), Hans Gelderblom (78206)   +10 more
core   +1 more source

Nobiletin alleviates cisplatin-induced ototoxicity via activating autophagy and inhibiting NRF2/GPX4-mediated ferroptosis

Scientific Reports
Nobiletin, a citrus polymethoxy flavonoid with antiapoptotic and antioxidative properties, could safeguard against cisplatin-induced nephrotoxicity and neurotoxicity.
Wenao Song, Li Zhang, Xiaolin Cui, Rongrong Wang, Jingyu Ma, Yue Xu, Yan Jin, Dawei Wang, Zhiming Lu   +8 more
doaj   +1 more source

Cisplatin-Induced Ototoxicity in Head and Neck Cancer: A Systematic Review of Current Evidence, Clinical Implications, and the Need for Standardized Monitoring. [PDF]

Curr Oncol
Mirabile A, Vukatana A, Guizzardi M, Vaccarello G, Giordano L, Addeo R.   +5 more
europepmc   +1 more source

Capsaicin Modulates DNA Damage Related Gene Expressions in Cisplatin-Induced Ototoxicity. [PDF]

Laryngoscope Investig Otolaryngol
Altun YK, Olgun Y, Kaynar AP, Aktaş S, Altun Z.   +4 more
europepmc   +1 more source