Results 81 to 90 of about 17,163 (245)

N-Acetylcysteine in the prevention of ototoxicity

open access: yes, 2007
Prevention of ototoxicity after the administration of aminoglycoside antibiotics has been notably difficult, in particular in patients with chronic kidney disease. Feldman et al.
Tepel, M.
core   +1 more source

Systematic review and scoring‐based selection of pharmacokinetic models for precision dosing of vancomycin in neonates and children

open access: yesBritish Journal of Clinical Pharmacology, Volume 92, Issue 7, Page 2028-2048, July 2026.
This systematic review identified 112 population pharmacokinetic models of vancomycin in neonates and children. To support rational model selection for model‐informed precision, we developed and applied expert‐driven, transparent criteria that integrate both methodological rigour and clinical relevance.
Zoë Vander Elst   +8 more
wiley   +1 more source

Preventing ototoxicity and its effects [PDF]

open access: yes, 2021
Although studies from many countries have shown that ototoxicity is not a major cause of hearing loss or balance problems, it is important as it is potentially preventable. It is more prevalent in low- and middle-income countries (LMICs) due to a lack of
Sirimanna, Tony   +2 more
core  

Fertility preservation access among female adolescents and young adults with cancer: A systematic review

open access: yesCancer, Volume 132, Issue 13, 1 July 2026.
Abstract Adolescents and young adults (AYAs; aged 15–39 years) with cancer face significant threats to future fertility. Despite fertility preservation (FP) guidelines, disparities in access persist, particularly among female AYAs. This systematic review aims to describe FP access and explore disparities by sociodemographic and clinical factors among ...
Marcela Algave   +3 more
wiley   +1 more source

J Toxicol Environ Health B Crit Rev [PDF]

open access: yes
To determine the state of the research on ototoxic properties of Pb, evaluate possible synergistic effects with concurrent noise exposure, and identify opportunities to improve future research, we performed a review of the peer-reviewed literature to ...

core  

Table2_Tetrandrine Prevents Neomycin-Induced Ototoxicity by Promoting Steroid Biosynthesis.XLSX

open access: yes, 2022
Aminoglycoside antibiotics are widely used for the treatment of serious acute infections, life-threatening sepsis, and tuberculosis, but all aminoglycosides cause side effects, especially irreversible ototoxicity.
Yan Yu (56143)   +10 more
core   +1 more source

Efficacy and Mechanisms of Antioxidant Compounds and Combinations Thereof against Cisplatin-Induced Hearing Loss in a Rat Model

open access: yesAntioxidants
Cisplatin is an election chemotherapeutic agent used for many cancer treatments. Its cytotoxicity against neoplastic cells is mirrored by that taking place in healthy cells and tissues, resulting in serious adverse events.
Liliana Carles   +6 more
doaj   +1 more source

The efficacy of strategies used to minimise or prevent Cisplatin-induced ototoxicity in patients

open access: yesSouth African Journal of Oncology, 2019
Background: Hearing loss is a major side effect of cisplatin-based chemotherapy. With a large burden of cancer in developing countries, an evidence-based approach to prevention of cisplatin-induced hearing loss (ototoxicity) is pertinent.
Zenzo S. Chakara, Lebogang Ramma
doaj   +1 more source

Hearing Loss in Adults With Diabetes and Prediabetes: A Systematic Review and Meta‐Analysis

open access: yesDiabetes/Metabolism Research and Reviews, Volume 42, Issue 5, July 2026.
ABSTRACT Diabetes impairs hearing through microvascular damage and neuropathy, yet the prevalence of moderate‐to‐severe hearing loss (≥ 40 dB HL) remains inadequately explored. Variations by age, diabetes duration, and socioeconomic factors are inadequately characterised. This systematic review quantified the prevalence and comparative risk of moderate‐
Mehwish Nisar   +4 more
wiley   +1 more source

Table10_Tetrandrine Prevents Neomycin-Induced Ototoxicity by Promoting Steroid Biosynthesis.XLSX

open access: yes, 2022
Aminoglycoside antibiotics are widely used for the treatment of serious acute infections, life-threatening sepsis, and tuberculosis, but all aminoglycosides cause side effects, especially irreversible ototoxicity.
Yan Yu (56143)   +10 more
core   +1 more source

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