Results 101 to 110 of about 17,163 (245)

Suppression of the TGF-β signaling exacerbates degeneration of auditory neurons in kanamycin-induced ototoxicity in mice

Scientific Reports
Transforming growth factor-β (TGF-β) signaling plays a significant role in multiple biological processes, including inflammation, immunity, and cell death. However, its specific impact on the cochlea remains unclear.
Yoshihiro Nitta, Takaomi Kurioka, Sachiyo Mogi, Hajime Sano, Taku Yamashita   +4 more
doaj   +1 more source

Evaluation of a New, Community‐Based Screening Program to Detect Hearing Loss in Adult Childhood Cancer Survivors in Switzerland: Findings From the HEAR Study

Pediatric Blood &Cancer, Volume 73, Issue 6, June 2026.
ABSTRACT Background Childhood cancer survivors (CCS) have an increased risk of long‐term health complications, including treatment‐related hearing loss. Although early detection is important, many adult survivors do not attend hearing screenings in clinical centers because visits can be logistically or emotionally burdensome.
Philippa Jörger, Carina Nigg, Christina Schindera, Maša Žarković, Grit Sommer, Martin Kompis, Annika Frahsa, Nicolas Waespe, Marc Ansari, Claudia E. Kuehni   +9 more
wiley   +1 more source

A dermatosurgically optimized ear tamponade technique to prevent external auditory canal obstruction – a method for secure closure

JDDG: Journal der Deutschen Dermatologischen Gesellschaft, EarlyView.
Martin Flatz, Sandra Schreiner, Christian Kunte   +2 more
wiley   +1 more source

SKOOTS: Skeleton‐Oriented Object Segmentation for Mitochondria in High‐Resolution Cochlear EM Datasets

Advanced Science, Volume 13, Issue 32, 9 June 2026.
Skeleton‐oriented object segmentation (SKOOTS) introduces a new strategy for 3D mitochondrial instance segmentation by predicting explicit skeletons rather than relying on boundary cues. This approach enables robust analysis of densely packed organelles in large FIB‐SEM datasets.
Christopher J. Buswinka, Richard T. Osgood, Hidetomi Nitta, Artur A. Indzhykulian   +3 more
wiley   +1 more source

Clinical Predictors of Cisplatin Chemoradiation-Induced Ototoxicity in HPV-Positive Oropharyngeal Squamous Cell Carcinoma: A Case-Control Study

Journal of Otolaryngology - Head and Neck Surgery
Background Cisplatin-based chemoradiation is a standard treatment for many patients with human papillomavirus (HPV)-positive oropharyngeal squamous cell carcinoma (OPSCC), an etiologically distinct subset of head and neck cancer. Although associated with
John JW. Lee MD, Salahaldin Alamleh BHSc, Luna Jia Zhan MPH, Katrina Hueniken MSc, Mary B. Mahler MD, Astrid Billfalk-Kelly MD, Joel Davies MD, M. Catherine Brown MSc, Anna Spreafico MD, Shao Hui Huang MSc, Andrew Hope MD, Wei Xu PhD, David P. Goldstein MD, Geoffrey Liu MD   +13 more
doaj   +1 more source

Antibiotic‐Impregnated Calcium Sulfate Beads for Local Therapy of Severe Skull Base Osteomyelitis

Clinical Case Reports, Volume 14, Issue 6, June 2026.
Novel Local Therapy of Severe Skull Base Osteomyelitis. ABSTRACT We report on a patient with severe progressive osteomyelitis of the lateral skull base, despite targeted long‐term antibiotic therapy. Successful treatment and recovery of the facial nerve palsy were achieved through additional surgical debridement and insertion of synthetic calcium ...
Stefan Lyutenski, Aviva Henze, Paul James, Marc Bloching   +3 more
wiley   +1 more source

Establishing a pharmacotherapy induced ototoxicity programme within a service-learning approach

South African Journal of Communication Disorders, 2015
Pharmacotherapy-induced ototoxicity is growing, especially in developing countries such as South Africa. This highlights the importance of ototoxicity monitoring and management of hearing loss.
Natalie Schellack, Anna M. Wium, Katerina Ehlert, Yolande van Aswegen, Andries Gous   +4 more
doaj   +1 more source

Bilateral Brucellar Sacroiliitis Mimicking Tuberculous or Inflammatory Spondyloarthropathy: A Case Report

Clinical Case Reports, Volume 14, Issue 6, June 2026.
ABSTRACT Brucellosis is a zoonotic infection, endemic in rural areas. It is caused by Brucella species, which are transmitted through the intake of unpasteurized dairy products and contact with infected animals. Sacroiliac joint involvement is common in brucellosis and typically presents as unilateral sacroiliitis. Contrarily, bilateral sacroiliitis is
Zia Ullah, Zain Ul Abedeen, Muhammad Kashif Habib, Naeem Ullah, Abad Ur Rehman   +4 more
wiley   +1 more source

Magnitude, Patterns and Factors Associated With Sensorineural Hearing Loss Among Hypertensive Adults at a Tertiary Hospital in Northern Tanzania

Eye &ENT Research, Volume 3, Issue 2, Page 101-106, June 2026.
ABSTRACT Background Hearing loss affects 1.5 billion people globally, with sensorineural hearing loss (SNHL) linked to hypertension. Hypertension affects 1.39 billion people worldwide and its prevalence is rising sharply in Sub‐Saharan Africa. While 12% of Tanzanian population has cardiovascular diseases, including hypertension and recent studies ...
Johnson Shayo, Denis Katundu, Abdallah Jonas, Peter Shija   +3 more
wiley   +1 more source

Audiologic monitoring of ototoxicity

, 2005
Ototoksisite, çe.itli terapötik ajanların veya kimyasal maddelerin iç kulak yapılarında veya fonksiyonlarında hasar yaratma etkisi olarak tanımlanabilir. Etkilenen kısım koklea, vestibül veya her ikisi olabilir. Ototoksisitenin başlıca semptomları işitme
Yağız, Recep, Taş, Abdullah
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