Results 111 to 120 of about 25,486 (236)

Ceruminolith removal and otitis externa in a 2‐year‐old male neutered red kangaroo (Osphranter rufus)

open access: yesVeterinary Record Case Reports, Volume 14, Issue 2, May 2026.
Abstract A 2‐year‐old, male, neutered red kangaroo (Osphranter rufus) presented for a 9‐month history of right‐sided otic pruritus, ear droop and otitis externa with suspected ceruminolith formation. At initial presentation, computed tomography of the skull was performed, which revealed a non‐contrast‐enhancing mass effect in the ear canal.
Christina Gentry, Alice Blue‐McLendon
wiley   +1 more source

Establishing a pharmacotherapy induced ototoxicity programme within a service-learning approach

open access: yesSouth African Journal of Communication Disorders, 2015
Pharmacotherapy-induced ototoxicity is growing, especially in developing countries such as South Africa. This highlights the importance of ototoxicity monitoring and management of hearing loss.
Natalie Schellack   +4 more
doaj   +1 more source

Dynamic Editome of Zebrafish under Aminoglycosides Treatment and Its Potential Involvement in Ototoxicity

open access: yesFrontiers in Pharmacology, 2017
RNA editing is an important co- and post-transcriptional event that generates RNA and protein diversity. Aminoglycosides are a group of bactericidal antibiotics and a mainstay of antimicrobial therapy for several life-threatening infections.
Sijia Yan   +11 more
doaj   +1 more source

Cellular signals of cisplatin ototoxicity [PDF]

open access: yes, 2011
Three separate theories of inhibiting cisplatin-induced apoptosis were investigated utilizing different cellular mechanisms. Specifically, the copper transport cycle, TRPV1, and the JNK pathway were inhibited and immunohistochemistry was performed to ...
Yarnell, Lindsey M
core   +1 more source

Role of RGS17 in cisplatin-induced cochlear inflammation and ototoxicity via caspase-3 activation

open access: yesFrontiers in Immunology
Cisplatin is a chemotherapy drug used to treat different solid tumors, including ovarian, bladder, lung, and head and neck cancers. One of its significant side effects is ototoxicity, especially when high doses are required. Cisplatin-induced ototoxicity
Raheem F. H. Al Aameri   +7 more
doaj   +1 more source

Genetic and temporal aspects of protection by kanamycin against cochlear noise injury [PDF]

open access: yes, 2010
Experiments explored the minimal kanamycin dosing regimen that renders protection against noise induced hearing loss in young CBA/J mice. We also tested the age-dependence of protection in CBA/J as well as the dependence of protection on a particular ...
Rosen, Allyson D
core   +1 more source

Synergistic effects of noise, kanamycin, and hyperoxia on ABR thresholds in CBA/J mice [PDF]

open access: yes, 2008
Young CBA/J mice were exposed to noise, kanamycin, and/or hyperoxia by 30 days post-gestational age in order to determine if a synergistic effect exists on ABR ...
Baum, Elizabeth Ann
core   +1 more source

The effect of anti-inflammatory drugs on hair cell regeneration in the zebrafish lateral line [PDF]

open access: yes, 2014
Hair cell death and regeneration on the three distal-most neuromasts in the posterior lateral line of zebrafish larvae were investigated after neomycin treatment.
Garbo, Sarah C
core   +1 more source

Hesperidin activates Nrf2 to protect cochlear hair cells from cisplatin-induced damage

open access: yesRedox Report
Cisplatin is widely employed in clinical oncology as an anticancer chemotherapy drug in clinical practice and is known for its severe ototoxic side effects.
Jintao Lou   +8 more
doaj   +1 more source

Efficacy of the Speech Intelligibility Index as an intervention tool with pediatric cancer patients [PDF]

open access: yes, 2010
This study evaluates the Speech Intelligibility Index (SII) as a tool to describe hearing loss and predict when hearing aids would be appropriate for pediatric oncology patients who have received or are currently receiving cisplatin.
Cahill, Megan
core   +1 more source

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