Scientific ReportsNobiletin, a citrus polymethoxy flavonoid with antiapoptotic and antioxidative properties, could safeguard against cisplatin-induced nephrotoxicity and neurotoxicity.
Wenao Song +8 more
doaj +1 more source
To develop behavioral tests of vestibular functioning in the Wistar rat [PDF]
Two tests of vestibular functioning in the rat were developed. The first test was the water maze. In the water maze the rat does not have the normal proprioceptive feedback from its limbs to help it maintain its orientation, and must rely primarily on ...
Nielson, H. C.
core +1 more source
Ototoxicity: a high risk to auditory function that needs to be monitored in drug development
Frontiers in Molecular NeuroscienceHearing loss constitutes a major global health concern impacting approximately 1.5 billion people worldwide. Its incidence is undergoing a substantial surge with some projecting that by 2050, a quarter of the global population will experience varying ...
Marie-Pierre Pasdelou +8 more
doaj +1 more source
Extrahepatic toxicity of acetaminophen: critical evaluation of the evidence and proposed mechanisms [PDF]
, 2017 Kennon-McGill, Stefanie +1 more
core +2 more sources
Genetic influences on early cochlear vulnerability to noise and protection from noise by low-dose kanamycin in hybrid mice [PDF]
, 2011 Experiments evaluated both noise vulnerability and the extent of protection from noise by sub-chronic low-dose kanamycin in young F1 hybrids resulting from a cross between C57BL/6J and CBA/J inbred ...
Barden, Emily Kathleen
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Chemotherapy Induced Hearing Loss and the Effects It Has on Learning [PDF]
, 2012 The purpose of this study was to determine whether the chemotherapy drug Cisplatin causes hearing loss significant enough to affect attention. Three groups of participants, all of which will have taken the drug Cisplatin, was sought to participate in ...
Smith, Sydney
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Efficacy and Tolerability of Antimalarials and Molecular Resistance Markers of Falciparum Malaria in Jimma Region, Ethiopia [PDF]
, 2011 Due to increasing drug resistance, artemisinin-based combination chemotherapy (ACT) has become the first-line treatment of falciparum malaria in many endemic countries.
Eshetu, Teferi
core
Pharmacogenetic strategies to mitigate cisplatin-induced ototoxicity in head and neck cancer: A cost-minimization analysis with the use of GSTP1 c.313A>G genotyping. [PDF]
PLoS OneMacedo LT +7 more
europepmc +1 more source
An integration of physiological, morphological and biochemical assessments in studying guinea pig models of ototoxicity and otoprotection-a systematic review. [PDF]
Curr Res ToxicolYoung YH, Wu PH, Liu SH.
europepmc +1 more source