Results 61 to 70 of about 17,163 (245)
Advances in GPCRs Associated With Wnt Signaling Within the Auditory System
Medicine Bulletin, EarlyView.ABSTRACT G protein‐coupled receptors (GPCRs) that interact with the Wnt signaling pathway are pivotal for auditory system homeostasis, as they orchestrate inner ear development, hair cell (HC) regeneration, and hearing preservation. Frizzled (FZD) receptors, the core Wnt‐related GPCRs, bind Wnt ligands and co‐receptors (e.g., LRP5/6) to activate both ...
Liang Wang +3 more
wiley +1 more source
Otolaryngology–Head and Neck Surgery, EarlyView.Abstract Objective To investigate the association between distortion product otoacoustic emission (DPOAE) signal‐to‐noise ratios (SNRs) and pure‐tone audiometry (PTA) thresholds in adolescents, both cross‐sectionally at age 18 and longitudinally by evaluating whether DPOAE SNRs at age 13 predict high‐frequency hearing loss (HFHL) at age 18.
Stefanie N. H. Reijers +5 more
wiley +1 more source
Effects of Asymmetric Auditory Deprivation in Sequential Cochlear Implant
Otolaryngology–Head and Neck Surgery, EarlyView.Abstract Objective To evaluate the influence of auditory deprivation on sequential cochlear implants in postlingual patients, comparing the ear with shorter deprivation (ESAD), longer deprivation (ELAD), and the bilateral condition (BIL). Study design Retrospective study. Setting A tertiary referral center.
Eduardo S. Farinazzo +4 more
wiley +1 more source
Concordance among different ototoxicity criteria.
, 2019 Concordance among different ototoxicity criteria.
B. Carleton (6335324) +5 more
core +1 more source
World Journal of Otorhinolaryngology - Head and Neck Surgery, EarlyView.ABSTRACT Objectives To evaluate the clinical impact of anatomy‐based fitting (ABF) in cochlear implants for patients with asymmetric hearing loss. Study Design Prospective cohort study. Setting Tertiary referral center specializing in hearing disorders.
Andrea Canale +6 more
wiley +1 more source
Monitoring Ototoxicity with DPOAEs [PDF]
, 2016 Ototoxicity is damage to the ears following exposure to medications. It is a common yet a preventable cause of hearing and/or balance problems. There are hundreds of drugs and chemicals that can cause hearing loss with the most established ototoxic drugs
Al-Malky, GMA
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ToxicsOtotoxicity refers to the adverse effects of substances on auditory or vestibular functions. This study examines the evidence of ototoxicity’s association with exposure to common environmental pollutants, as documented in toxicological profiles by the ...
Gregory M. Zarus +6 more
doaj +1 more source
Impact of Treatment Intensity on Quality of Life in Patients With Metastatic Testicular Cancer
Andrology, EarlyView.ABSTRACT Introduction Testicular cancer (TC) is the most common malignancy in young men and is highly curable with platinum‐based chemotherapy. With growing survivorship rates, treatment‐related symptom burden and quality of life (QoL) have become increasingly important.
Pailin Pongratanakul +6 more
wiley +1 more source
Platinum-based compounds used for treating hematologic malignancies can lead to various side effects. One such side effect is ototoxicity, which is characterized by permanent bilateral sensorineural hearing loss or tinnitus.
Aleksandra Janowiak-Majeranowska +3 more
core +1 more source
, 2023 Introduction: Nearly half of the patients who underwent chemotherapy received cisplatin as part of their regimen. Cisplatin-induced hearing loss generally starts at high frequencies first and can affect the speech frequency range after prolonged use ...
Awad, Asma Rafa. A.
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