Results 51 to 60 of about 17,163 (245)
Current Strategies to Combat Cisplatin-Induced Ototoxicity
Frontiers in Pharmacology, 2020 Cisplatin is widely used for the treatment of a number of solid malignant tumors. However, ototoxicity induced by cisplatin is an obstacle to effective treatment of tumors. The basis for this toxicity has not been fully elucidated.
Dehong Yu +17 more
doaj +1 more source
Journal of Applied Toxicology, EarlyView.ABSTRACT This study aimed to evaluate whether polydatin (Poly) could eliminate the harmful effects of vancomycin (VCM) on the lungs of rats. Rats were administered VCM (200 mg/kg) and Poly (50 mg/kg), both separately and in combination, for a duration of 7 days.
Serpil Aygörmez +6 more
wiley +1 more source
Systemic ototoxicity: a review
, 2006 Background: Systemic ototoxicity is a significant cause of vestibulocochlear morbidity in sub-Saharan Africa. It may result in permanent hearing impairment and/or balance problems.Objectives: To review the literature pertaining to the ototoxic potential ...
Shine, NP, NP Shine, Coates, H, H Coates
core +1 more source
PLoS ONEAimThe perspectives and practices of healthcare professionals regarding ototoxicity in individuals with head and neck cancers are important for the implementation of ototoxicity monitoring. The current study aims to explore the oncologist's awareness and
Varsha Shankar +4 more
doaj +1 more source
Cisplatin ototoxicity mechanism and antagonistic intervention strategy: a scope review
Frontiers in Cellular Neuroscience, 2023 Cisplatin is a first-line chemotherapeutic agent in the treatment of malignant tumors with remarkable clinical effects and low cost. However, the ototoxicity and neurotoxicity of cisplatin greatly limit its clinical application.
Yingru Li +29 more
doaj +1 more source
Radiotherapy‐Induced Otitis Media With Effusion in Nasopharyngeal Carcinoma: A Meta‐Analysis
The Laryngoscope, EarlyView.This meta‐analysis of eight studies comprising 582 NPC patients provides the first quantitative synthesis of radiotherapy‐induced otitis media with effusion (OME), demonstrating a significant overall risk difference of 0.18 (95% CI: −0.06 to 0.42, p < 0.0001) in OME naive ears.
Nevin Yi Meng Chua +3 more
wiley +1 more source
Cisplatin-induced ototoxicity: the current state of ototoxicity monitoring in New Zealand. [PDF]
, 2011 Background: Many well-known pharmacologic agents have been shown to have toxic effects to the cochleo-vestibular system. Examples of such ototoxic agents include cisplatin and aminoglycoside antibiotics. Ototoxicity monitoring consists of a comprehensive
Venter, Kinau
core +1 more source
Disparities in Hearing Screening Practices in Minnesota Elementary Schools
The Laryngoscope, EarlyView.ABSTRACT Objective Identifying and addressing pediatric hearing loss is critical to supporting a child's development. School‐based hearing screening is a mainstay of timely identification of hearing loss. The objectives of this study were to characterize the current hearing screening practices in public, charter, and private elementary schools in ...
Autefeh Sajjadi +12 more
wiley +1 more source
ViewIt is widely recognized that platinum‐based chemotherapy, particularly cisplatin therapy, can cause ototoxicity. At present, there are no Food and Drug Administration‐approved drugs to prevent or alleviate ototoxicity.
Yaqin Tu +8 more
doaj +1 more source
Ménière's Disease: A Tri‐Decade Scoping Review of Treatment Trends and Evidence Quality
The Laryngoscope, EarlyView.This tri‐decade scoping review of Ménière's disease literature reveals a significant increase in high‐level evidence and a clinical pivot toward hearing‐preserving interventions, such as intratympanic steroids and cochlear implants. However, a significant quality paradox has emerged, where adherence to standardized AAO‐HNS reporting and diagnostic ...
Ofir Zavdy +4 more
wiley +1 more source