Results 41 to 50 of about 19,052 (152)

(-)-Epigallocatechin-3-gallate protects against NO-induced ototoxicity through the regulation of caspase- 1, caspase-3, and NF-κB activation. [PDF]

PLoS ONE, 2012
Excessive nitric oxide (NO) production is toxic to the cochlea and induces hearing loss. However, the mechanism through which NO induces ototoxicity has not been completely understood.
Su-Jin Kim, Jeong-Han Lee, Beom-Su Kim, Hong-Seob So, Raekil Park, Noh-Yil Myung, Jae-Young Um, Seung-Heon Hong   +7 more
doaj   +1 more source

Table10_Tetrandrine Prevents Neomycin-Induced Ototoxicity by Promoting Steroid Biosynthesis.XLSX

, 2022
Aminoglycoside antibiotics are widely used for the treatment of serious acute infections, life-threatening sepsis, and tuberculosis, but all aminoglycosides cause side effects, especially irreversible ototoxicity.
Yan Yu (56143), Chen Zhang (66790), Jieyu Qi (7105475), Yuguang Niu (11387679), Yunhao Wu (4604983), Xin Chen (14149), Geping Wu (10183164), Renjie Chai (276884), Qilei Zhang (12433341), Qiaojun Fang (211668), Kaiming Su (491616)   +10 more
core   +1 more source

Oncologists' views on ototoxicity monitoring in head and neck cancer patients: A South Indian qualitative study.

PLoS ONE
AimThe perspectives and practices of healthcare professionals regarding ototoxicity in individuals with head and neck cancers are important for the implementation of ototoxicity monitoring. The current study aims to explore the oncologist's awareness and
Varsha Shankar, Jayashree Seethapathy, Satish Srinivas, Raghu Nandhan, Prasanna Kumar Saravanam   +4 more
doaj   +1 more source

Cisplatin Ototoxicity: Where We Are?

, 2013
Objective: Ototoxicity is a dose limiting side effect of Cisplatin based chemotherapy protocols. Currently there is no approved agent against Cisplatin ototoxicity.
Olgun, YÜKSEL
core   +1 more source

Knowledge of final year medicine, pharmacy, audiology and nursing students in South Africa on drug-induced ototoxicity: A pilot study

South African Journal of Communication Disorders, 2019
Background: There is a high prevalence of human immunodeficiency virus (HIV), tuberculosis (TB), cancer and malaria in South Africa, and the drugs used to treat these conditions can be ototoxic. It is therefore important that healthcare professionals are
Omphile Mogole, Natalie Schellack, Cara Hollander, Lebogang Ramma   +3 more
doaj   +1 more source

The Mechanotransduction Channel and Organic Cation Transporter Are Critical for Cisplatin Ototoxicity in Murine Hair Cells

Frontiers in Molecular Neuroscience, 2022
Cisplatin is one of the most widely used chemotherapeutic drugs across the world. However, the serious ototoxic effects, leading to permanent hair cell death and hearing loss, significantly limit the utility of cisplatin.
Jinan Li, Chang Liu, Samuel Kaefer, Mariam Youssef, Bo Zhao   +4 more
doaj   +1 more source

Concordance among different ototoxicity criteria.

, 2019
Concordance among different ototoxicity criteria.
B. Carleton (6335324), B. Brooks (6335315), M. M. van den Heuvel-Eibrink (6059804), A. C. H. de Vries (6335318), E. Clemens (6335312), M. van Grotel (6335321)   +5 more
core   +1 more source

Table4_Tetrandrine Prevents Neomycin-Induced Ototoxicity by Promoting Steroid Biosynthesis.XLSX

, 2022
Aminoglycoside antibiotics are widely used for the treatment of serious acute infections, life-threatening sepsis, and tuberculosis, but all aminoglycosides cause side effects, especially irreversible ototoxicity.
Yan Yu (56143), Chen Zhang (66790), Jieyu Qi (7105475), Yuguang Niu (11387679), Yunhao Wu (4604983), Xin Chen (14149), Geping Wu (10183164), Renjie Chai (276884), Qilei Zhang (12433341), Qiaojun Fang (211668), Kaiming Su (491616)   +10 more
core   +1 more source

Perspectives and practices of ototoxicity monitoring

South African Journal of Communication Disorders, 2020
Background: Treatment of cancer with cisplatin can result in hearing loss. Given the increasing burden of cancer in Africa, appropriate and timely identification, intervention and management of hearing loss in affected patients is of paramount importance.
Jessica Paken, Cyril D. Govender, Mershen Pillay, Vikash Sewram   +3 more
doaj   +1 more source

Table12_Tetrandrine Prevents Neomycin-Induced Ototoxicity by Promoting Steroid Biosynthesis.XLSX

, 2022
Aminoglycoside antibiotics are widely used for the treatment of serious acute infections, life-threatening sepsis, and tuberculosis, but all aminoglycosides cause side effects, especially irreversible ototoxicity.
Yan Yu (56143), Chen Zhang (66790), Jieyu Qi (7105475), Yuguang Niu (11387679), Yunhao Wu (4604983), Xin Chen (14149), Geping Wu (10183164), Renjie Chai (276884), Qilei Zhang (12433341), Qiaojun Fang (211668), Kaiming Su (491616)   +10 more
core   +1 more source