Quantitative Analysis of Gentamicin Exposure in Neonates and Infants Calls into Question Its Current Dosing Recommendations. [PDF]
Optimal dosing of gentamicin in neonates is still a matter of debate despite its common use. We identified gentamicin dosing regimens from eight international guidelines and seven Swiss neonatal intensive care units.
Bielicki, J +6 more
core +2 more sources
Platinum-based compounds used for treating hematologic malignancies can lead to various side effects. One such side effect is ototoxicity, which is characterized by permanent bilateral sensorineural hearing loss or tinnitus.
Aleksandra Janowiak-Majeranowska +3 more
doaj +1 more source
Background: A significant number of medications that are prescribed by doctors to treat cancers, tuberculosis and infections are ototoxic. Disclosure of ototoxic risks is ethical practice as patients have the right to be properly informed about and ...
Anna Wium, Berna Gerber
doaj +1 more source
Evaluation of insert earphones for high-frequency bedside ototoxicity monitoring
Ototoxic hearing loss is usually detected earliest through monitoring of the highest audible frequencies in individuals administered ototoxic medications. Conducting ototoxicity monitoring may require testing patients in the hospital room. This study evaluated the use of insert earphones for obtaining reliable threshold responses at bedside.
Jane S, Gordon +4 more
openaire +2 more sources
Aminoglycoside-induced hearing deficits – a review of cochlear ototoxicity
This article aims to inform the reader about current knowledge of the effects of aminoglycosides on hearing. The hearing loss caused by aminoglycosides is permanent and can negatively affect the individual’s quality of life.
Lucretia Petersen, Christine Rogers
doaj +1 more source
Aminoglycosides for Intra-Abdominal Infection: Equal to the Challenge? [PDF]
Background: Aminoglycosides, combined with antianaerobic agents, have been used widely for the treatment of intra-abdominal infection. However, some prospective randomized controlled trials and other data suggested that aminoglycosides were less ...
Bailey, John A. +5 more
core +1 more source
Efficacy and Tolerability of Antimalarials and Molecular Resistance Markers of Falciparum Malaria in Jimma Region, Ethiopia [PDF]
Due to increasing drug resistance, artemisinin-based combination chemotherapy (ACT) has become the first-line treatment of falciparum malaria in many endemic countries.
Eshetu, Teferi
core
Delayed Complete Spontaneous Hearing Recovery in a Pediatric Chemotherapy Patient—A Case Report
OTO Open, Volume 10, Issue 2, April-June 2026.
Mihai A. Bentan +3 more
wiley +1 more source
Review of multidrug-resistant and extensively drug-resistant TB: global perspectives with a focus on sub-Saharan Africa [PDF]
Tuberculosis (TB) remains a global emergency and is responsible for 1.7 million deaths annually. Widespread global misuse of isoniazid and rifampicin over three decades has resulted in emergence of the ominous spread of multidrug-resistant TB (MDR-TB ...
Abdool Karim +70 more
core +1 more source
Measuring the Effects of Furosemide on Lung Mechanics Using Oscillometry in Preterm Infants
Pediatric Pulmonology, Volume 61, Issue 4, April 2026.
Colm P. Travers +4 more
wiley +1 more source

