Results 101 to 110 of about 4,708 (180)

In vivo screening for toxicity-modulating drug interactions identifies antagonism that protects against ototoxicity in zebrafish

Frontiers in Pharmacology
Introduction: Ototoxicity is a debilitating side effect of over 150 medications with diverse mechanisms of action, many of which could be taken concurrently to treat multiple conditions.
Ethan Bustad, Emma Mudrock, Elizabeth M. Nilles, Andrea Mcquate, Andrea Mcquate, Andrea Mcquate, Monica Bergado, Alden Gu, Louie Galitan, Natalie Gleason, Henry C. Ou, Henry C. Ou, David W. Raible, David W. Raible, David W. Raible, Rafael E. Hernandez, Rafael E. Hernandez, Shuyi Ma, Shuyi Ma, Shuyi Ma, Shuyi Ma   +20 more
doaj   +1 more source

Ototoxicity Monitoring using Automated Extended High-Frequency Audiometry and the Sensitive Range of Ototoxicity in Patients with MDR-TB

, 2021
Background: Disabling hearing loss is a global burden. This burden is worsened by the emergence of multi-drug resistant tuberculosis (MDR-TB). Some of the medications used to treat MDR-TB are damaging to the cochlea and auditory nerve (ototoxic) and can ...
Greeff, Wildine Marion
core  

Ototoxicity Monitoring Protocols for Common Chemotherapeutics

Cancer is a major public health concern and is increasingly prevalent worldwide. Sung et al. (2021) states that there were 19.3 million new cases of cancer across the globe, and almost 10 million deaths related to cancer in 2021. Sung et al.
Kennedy, Megan Pamela
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Monitoring carboplatin ototoxicity with distortion-product otoacoustic emissions in children with retinoblastoma

, 2010
ObjectiveCarboplatin is a common chemotherapy agent with potential ototoxic side effects that is used to treat a variety of pediatric cancers, including retinoblastoma.
Matthew W. Wilson, Jianrong Wu, Qaddoumi, Ibrahim, Wilson, Matthew, Shaum P. Bhagat, Stephanie T. White, Ibrahim Qaddoumi, Bass, Johnnie, Rodriguez-Galindo, Carlos, Wu, Jianrong, Carlos Rodriguez-Galindo, White, Stephanie, Bhagat, Shaum, Johnnie K. Bass   +13 more
core   +1 more source

Long-Term Variability of Distortion-Product Otoacoustic Emissions in Infants and Children and Its Relation to Pediatric Ototoxicity Monitoring. [PDF]

Ear Hear, 2020
Konrad-Martin D, Knight K, McMillan GP, Dreisbach LE, Nelson E, Dille M.   +5 more
europepmc   +1 more source

Ototoxicity Associated with Oxaliplatin in a Patient with Pancreatic Cancer

, 2013
Context Oxaliplatin, a third-generation platinum derivative is commonly used for the treatment of colorectal cancer, pancreatic cancer, upper gastrointestinal cancer, hepatobiliary cancer, and ovarian cancer.
Rodriguez, Gladys, Wasif, Nawal, Oh, Sun Young, Saif, Muhammad Wasif, Garcon, Marie Carmel   +4 more
core   +1 more source

A profile of the auditory function of children with TB receiving ototoxic medication at Brooklyn Chest Hospital

, 2012
Includes abstract.Includes bibliographical references.A descriptive survey research design was used to describe the auditory function of children with tuberculosis (TB) receiving ototoxic medication at Brooklyn Chest Hospital.
Ghafari, Nazanin
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A review: Pharmaceutical induced ototoxicity

Ototoxicity, defined as drug-induced damage to the auditory and vestibular systems, manifests as hearing loss, tinnitus, dizziness, and balance disorders, representing a critical challenge in clinical practice and pharmaceutical development.
Oltulu, Cagatay, Dasman, Mustafa
core   +1 more source

Ototoxicity: Early Detection and Monitoring

The ASHA Leader, 2005
Dawn Konrad-Martin, Wendy J. Helt, Kelly M. Reavis, Jane S. Gordon, Laura L. Coleman, Gene W. Bratt, Stephen A. Fausti   +6 more
openaire   +1 more source

An analysis of ototoxicity in children: Audiological detection, clinical practice and genetic susceptibility [PDF]

, 2014
Ototoxicity is the damage to the ear from exposure to medications. The inner ear is the commonest site of damage where cochlear and/or vestibular functions are affected. Ototoxic medications can cause irreversible toxicity, with aminoglycosides (AGs) and
Al-Malky, GMA
core