Results 91 to 100 of about 2,606,163 (178)

Cisplatin associated ototoxicity in patients receiving cancer chemotherapy in a tertiary care hospital

open access: yesNational Journal of Physiology, Pharmacy and Pharmacology, 2020
Background: Cisplatin-based treatment regimen has been a gold standard in the treatment of various solid tumors. Ototoxicity is a very serious adverse effect of cisplatin therapy in either high or low dose regimens.
Nalini R   +4 more
doaj   +1 more source

Real‐World Management of Difficult Exacerbations of Bronchiectasis: A Case Study to Illustrate How Guidelines Can Support Best Practice

open access: yesClinical Case Reports, Volume 14, Issue 10, October 2026.
ABSTRACT Timely management of exacerbations and optimisation of ongoing care are vital in preventing disease progression and preserving outcomes and quality of life in patients with bronchiectasis. This retrospective case review underscores the importance of the new ERS guidelines in supporting multidisciplinary teams to provide optimal care for their ...
Hulance Bianca   +3 more
wiley   +1 more source

Extended-Interval Dosing of Aminoglycosides in Pediatrics: A Narrative Review

open access: yesJournal of Pediatrics Review, 2015
Aminoglycosides (AGs) are frequently used in pediatric settings, especially for empiric treatment of early-onset neonatal sepsis. Although AGs are used for several decades, the optimum method of administration and their dosing schemes needs more ...
Ebrahim Salehifar, Mohammad Reza Rafati
doaj   +2 more sources

Ototoxicity and otoprotection in the inner ear of guinea pigs using gentamicin and amikacin: ultrastructural and functional aspects

open access: yesBrazilian Journal of Otorhinolaryngology, 2008
Summary: Ototoxicity is still a challenge to medicine. The discovery of self-protecting endogenous mechanisms of the outer hair cells associated with their functional and ultra-structural assessment methods has opened new horizons in the understanding ...
Thomaz José Marra de Aquino   +2 more
doaj   +1 more source

Highly active antiretroviral therapy: Does it Sound toxic?

open access: yesJournal of Pharmacy and Bioallied Sciences, 2011
Objective : The main objective of the current study is to monitor the auditory status in a group of adults with AIDS, receiving Highly Active Antiretroviral Therapy (HAART) (3TC -lamivudine, D4T - stavudine, and efavirenz) in a hospital outpatient clinic
Katijah Khoza-Shangase
doaj   +1 more source

Evaluation of insert earphones for high-frequency bedside ototoxicity monitoring

open access: yesThe Journal of Rehabilitation Research and Development, 2004
Ototoxic hearing loss is usually detected earliest through monitoring of the highest audible frequencies in individuals administered ototoxic medications. Conducting ototoxicity monitoring may require testing patients in the hospital room. This study evaluated the use of insert earphones for obtaining reliable threshold responses at bedside.
Jane S, Gordon   +4 more
openaire   +2 more sources

Ototoxicity Induced by Cinnabar (a Naturally Occurring Hgs) in Mice through Oxidative Stress and down-Regulated Na+/K+-Atpase Activities

open access: yes, 2009
Cinnabar, a naturally occurring mercuric sulfide (HgS), has long been used in Chinese mineral medicine for more than 2000 years; currently it is still used as a sedative for infants in Asian countries.
黃俊發;許權振;劉興華;蕭水銀   +1 more
core   +1 more source

Evoked otoacoustic emissions — an approach for monitoring cisplatin induced ototoxicity in children

open access: yesInternational Journal of Pediatric Otorhinolaryngology, 2001
Cisplatin chemotherapy is associated with an increased risk of ototoxic changes. The incidence of hearing loss after the 1st cisplatin-infusion session is only scarcely mentioned in the international literature. With increasing survival rates, prevention and/or early detection of ototoxicity are important for providing management options.
Stavroulaki, P   +4 more
openaire   +3 more sources

Serial Assessment of Cochlear Changes Using Transient Evoked and Distortion Product Otoacoustic Emissions in Children Receiving Platinum-Based Chemotherapy

open access: yesNational Board of Examinations Journal of Medical Sciences
Background: Advances in platinum-based chemotherapy have improved childhood cancer survival, but ototoxicity remains a major complication, particularly in younger children. This prospective study evaluated serial cochlear changes using TEOAE and DPOAE to
Monica Mrudubhashini Michael   +6 more
doaj   +1 more source

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