Results 71 to 80 of about 4,708 (180)

Cisplatin associated ototoxicity in patients receiving cancer chemotherapy in a tertiary care hospital

National Journal of Physiology, Pharmacy and Pharmacology, 2020
Background: Cisplatin-based treatment regimen has been a gold standard in the treatment of various solid tumors. Ototoxicity is a very serious adverse effect of cisplatin therapy in either high or low dose regimens.
Nalini R, Ezhilramya J, Arumugham R, Suresh Kumar R, Celiba G   +4 more
doaj   +1 more source

Bacterial Ghosts as Innovative Transport Vehicles for Platinum‐Based Anticancer Drugs

ChemMedChem, Volume 21, Issue 12, 26 June 2026.
Bacterial ghosts (BGs), empty envelopes of Gram‐negative E. coli, are introduced as versatile carriers for platinum anticancer drugs. Oxaliplatin (OXA) shows high loading, stability, and reproducible encapsulation, while retaining full cytotoxicity in vitro.
Irena Pashkunova‐Martic, Matthias H. M. Klose, Pavol Kudela, Diana Groza‐Weber, Siegfried Reipert, Christian R. Kowol, Petra Heffeter, Walter Berger, Bernhard K. Keppler, Werner Lubitz   +9 more
wiley   +1 more source

Extended-Interval Dosing of Aminoglycosides in Pediatrics: A Narrative Review

Journal of Pediatrics Review, 2015
Aminoglycosides (AGs) are frequently used in pediatric settings, especially for empiric treatment of early-onset neonatal sepsis. Although AGs are used for several decades, the optimum method of administration and their dosing schemes needs more ...
Ebrahim Salehifar, Mohammad Reza Rafati
doaj   +2 more sources

Ototoxicity and otoprotection in the inner ear of guinea pigs using gentamicin and amikacin: ultrastructural and functional aspects

Brazilian Journal of Otorhinolaryngology, 2008
Summary: Ototoxicity is still a challenge to medicine. The discovery of self-protecting endogenous mechanisms of the outer hair cells associated with their functional and ultra-structural assessment methods has opened new horizons in the understanding ...
Thomaz José Marra de Aquino, José Antônio Apparecido de Oliveira, Maria Rossato   +2 more
doaj   +1 more source

Evaluation of a New, Community‐Based Screening Program to Detect Hearing Loss in Adult Childhood Cancer Survivors in Switzerland: Findings From the HEAR Study

Pediatric Blood &Cancer, Volume 73, Issue 6, June 2026.
ABSTRACT Background Childhood cancer survivors (CCS) have an increased risk of long‐term health complications, including treatment‐related hearing loss. Although early detection is important, many adult survivors do not attend hearing screenings in clinical centers because visits can be logistically or emotionally burdensome.
Philippa Jörger, Carina Nigg, Christina Schindera, Maša Žarković, Grit Sommer, Martin Kompis, Annika Frahsa, Nicolas Waespe, Marc Ansari, Claudia E. Kuehni   +9 more
wiley   +1 more source

A proposed ototoxicity monitoring protocol based on specificity, feasibility, and early identification [PDF]

, 2018
Senior capstone poster, Department of Communication Sciences and Disorders, SUNY PlattsburghOtotoxicity is damage to inner ear structures resulting from exposure to an ototoxic medication.
Moser, Caitlin
core   +1 more source

Antibiotic‐Impregnated Calcium Sulfate Beads for Local Therapy of Severe Skull Base Osteomyelitis

Clinical Case Reports, Volume 14, Issue 6, June 2026.
Novel Local Therapy of Severe Skull Base Osteomyelitis. ABSTRACT We report on a patient with severe progressive osteomyelitis of the lateral skull base, despite targeted long‐term antibiotic therapy. Successful treatment and recovery of the facial nerve palsy were achieved through additional surgical debridement and insertion of synthetic calcium ...
Stefan Lyutenski, Aviva Henze, Paul James, Marc Bloching   +3 more
wiley   +1 more source

Highly active antiretroviral therapy: Does it Sound toxic?

Journal of Pharmacy and Bioallied Sciences, 2011
Objective : The main objective of the current study is to monitor the auditory status in a group of adults with AIDS, receiving Highly Active Antiretroviral Therapy (HAART) (3TC -lamivudine, D4T - stavudine, and efavirenz) in a hospital outpatient clinic
Katijah Khoza-Shangase
doaj   +1 more source

Vancomycin intoxication in a patient with inappropriate antidiuretic hormone syndrome and diarrhea [PDF]

Farmacia Hospitalaria, 2015
Vancomycin is an antibiotic used for infections by gram-positive bacteria with a two-compartment pharmacokinetic model. Its monitoring has an established therapeutic range (10-20 mg/L) to prevent nephrotoxicity and ototoxicity due to supratherapeutic ...
Patricia Hidalgo-Collazos, Cristina López González-Cobos, Paula Arrabal-Durán, María Sanjurjo-Sáez   +3 more
doaj   +1 more source

Otoacoustic Emissions for Monitoring Aminoglycoside-Induced Ototoxicity in Children With Cystic Fibrosis [PDF]

Archives of Otolaryngology–Head & Neck Surgery, 2002
To investigate whether transient-evoked and distortion-product (DP) otoacoustic emissions (OAEs) are more sensitive than pure-tone audiometry (PTA) in revealing gentamicin-induced ototoxicity in children with cystic fibrosis (CF).Prospective case-control study.Tertiary referral audiologic center in conjunction with an academic pediatric CF unit.The ...
Stavroulaki, P, Vossinakis, IC, Dinopoulou, D, Doudounakis, S, Adamopoulos, G, Apostolopoulos, N   +5 more
openaire   +3 more sources