Results 71 to 80 of about 8,213 (210)

Ménière's Disease: A Tri‐Decade Scoping Review of Treatment Trends and Evidence Quality

The Laryngoscope, EarlyView.
This tri‐decade scoping review of Ménière's disease literature reveals a significant increase in high‐level evidence and a clinical pivot toward hearing‐preserving interventions, such as intratympanic steroids and cochlear implants. However, a significant quality paradox has emerged, where adherence to standardized AAO‐HNS reporting and diagnostic ...
Ofir Zavdy, Teeraya Piyajarawong, Seamus Boyle, Ross O'Shea, John Rutka   +4 more
wiley   +1 more source

Extended-Interval Dosing of Aminoglycosides in Pediatrics: A Narrative Review

Journal of Pediatrics Review, 2015
Aminoglycosides (AGs) are frequently used in pediatric settings, especially for empiric treatment of early-onset neonatal sepsis. Although AGs are used for several decades, the optimum method of administration and their dosing schemes needs more ...
Ebrahim Salehifar, Mohammad Reza Rafati
doaj   +2 more sources

Risk versus benefit: Who assesses this in the management of patients on ototoxic drugs?

Journal of Pharmacy and Bioallied Sciences, 2017
The current paper is an attempt at highlighting important strategic indicators, as well as important variables, that the audiology community needs to consider in order to play a more central role in pharmaco-vigilance as part of pharmaco-audiology ...
Katijah Khoza-Shangase
doaj   +1 more source

Cisplatin associated ototoxicity in patients receiving cancer chemotherapy in a tertiary care hospital

National Journal of Physiology, Pharmacy and Pharmacology, 2020
Background: Cisplatin-based treatment regimen has been a gold standard in the treatment of various solid tumors. Ototoxicity is a very serious adverse effect of cisplatin therapy in either high or low dose regimens.
Nalini R, Ezhilramya J, Arumugham R, Suresh Kumar R, Celiba G   +4 more
doaj   +1 more source

Intravesical therapy for recurrent urinary tract infection: a systematic review and meta‐analysis

BJU International, EarlyView.
Objective To undertake a systematic review and meta‐analysis to evaluate the efficacy, safety, and clinical applicability of intravesical instillations for preventing recurrent urinary tract infections (rUTIs). Methods PubMed/MEDLINE, Embase, Cochrane CENTRAL, Scopus, and Web of Science were searched from January 2000 to April 2025 for randomised and ...
Matthew Kwon, Asaad Ahmad, Natalie Lott, Alison Blatt   +3 more
wiley   +1 more source

Gentamicin affects the bioenergetics of isolated mitochondria and collapses the mitochondrial membrane potential in cochlear sensory hair cells [PDF]

, 2019
Aminoglycoside antibiotics are widely prescribed to treat a variety of serious bacterial infections. They are extremely useful clinical tools, but have adverse side effects such as oto- and nephrotoxicity.
Abuelezz, Alharazneh, Anthony L. Moore, Bendirdjian, Bendirdjian, Chen, Clerici, Corné J. Kros, Dehne, Ding, Eltahawy, Esterberg, Esterberg, Esterberg, Felix, Forge, Gonzalez, Gray, Gray, Guy P. Richardson, Hailey, He, Hirose, Hobbie, Jensen-Smith, Kluckova, Knight, Kornguth, Krumschnabel, Lash, Lesniak, Long, Lotz, Luke Young, Marcotti, Margulis, Medja, Mingeot-Leclercq, Molly O’Reilly, Nagai, Nerissa K. Kirkwood, Oliveira, Olszewska, O’Sullivan, Prezant, Rahn, Rizzi, Rohlena, Sahu, Schacht, Selimoglu, Servais, Sha, Simmons, Simmons, Skinner, Steyger, Walker, Wargo, Weinberg, Xie, Yang, Åkerman   +62 more
core   +1 more source

Re-telling the story of aminoglycoside ototoxicity: tales from sub-Saharan Africa

Frontiers in Neurology
BackgroundAminoglycosides, such as Streptomycin, are cheap, potent antibiotics widely used Sub-Saharan Africa. However, aminoglycosides are the commonest cause of ototoxicity.
Adebolajo A. Adeyemo, Adebolajo A. Adeyemo, Babatunde Adedokun, Josephine Adeolu, Joshua O. Akinyemi, Olayemi O. Omotade, Odunayo M. Oluwatosin   +6 more
doaj   +1 more source

Evaluation of a New, Community‐Based Screening Program to Detect Hearing Loss in Adult Childhood Cancer Survivors in Switzerland: Findings From the HEAR Study

Pediatric Blood &Cancer, Volume 73, Issue 6, June 2026.
ABSTRACT Background Childhood cancer survivors (CCS) have an increased risk of long‐term health complications, including treatment‐related hearing loss. Although early detection is important, many adult survivors do not attend hearing screenings in clinical centers because visits can be logistically or emotionally burdensome.
Philippa Jörger, Carina Nigg, Christina Schindera, Maša Žarković, Grit Sommer, Martin Kompis, Annika Frahsa, Nicolas Waespe, Marc Ansari, Claudia E. Kuehni   +9 more
wiley   +1 more source

Audiological monitoring of cisplatin exposed patients [PDF]

, 2003
Cisplatin is an antineoplasic drug, which has ototoxicity as a side effect. The goals of this paper were to evaluate the audiological behavior in osteosarcoma patients treated with cisplatin and to verify which evaluation method is the best for early ...
Garcia, Adriana Pontin [UNIFESP], Iorio, Maria Cecilia Martinelli [UNIFESP], Petrilli, Antonio Sergio [UNIFESP]   +2 more
core   +4 more sources

Once-daily versus multiple-daily dosing with intravenous aminoglycosides for cystic fibrosis [PDF]

, 2014
Background: People with cystic fibrosis, who are chronically colonised with the organism Pseudomonas aeruginosa, often require multiple courses of intravenous aminoglycoside antibiotics for the management of pulmonary exacerbations.
Bhatt, Jayesh, Smyth, Alan R.
core   +4 more sources