Results 91 to 100 of about 29,179 (204)

Electrogenic transport and K(+) ion channel expression by the human endolymphatic sac epithelium. [PDF]

, 2015
The endolymphatic sac (ES) is a cystic organ that is a part of the inner ear and is connected to the cochlea and vestibule. The ES is thought to be involved in inner ear ion homeostasis and fluid volume regulation for the maintenance of hearing and ...
Choi, Jae Young, Jung, JinSei, Kim, Bo Gyung, Kim, Jin Young, Kim, Sung Huhn, Moon, In Seok, Moon, Sung K, Roh, Kyung Jin, Suh, Michelle J   +8 more
core   +7 more sources

Adynamia episodica hereditaria with myotonia: A non-inactivating sodium current and the effect of extracellular pH [PDF]

, 1987
To study the mechanism of periodic paralysis, we investigated the properties of intact muscle fibers biopsied from a patient who had adynamia episodica hereditaria with electromyographic signs of myotonia.
Aickin, Becker, Bekény, Bradley, Bretag, Buchthal, Caldwell, Carson, Clausen, Drager, French, Gamstorp, Grafe, Grafe, Helweg-Larsen, Heuser, Hille, Hoff van't, Krull, Kwieciński, Kwieciński, Lehmann-Horn, Lehmann-Horn, Lehmann-Horn, Lewis, McArdle, McComas, Meulen van der, Ricker, Ricker, Riggs, Ruff, Rüdel, Rüdel, Stafstrom, Subramony, Sugimori, Thomas   +37 more
core   +1 more source

Na+,K+-ATPase is the membrane receptor of hormone ouabain

Communicative & Integrative Biology, 2010
At 10 nM, ouabain elicits changes in cell contacts, which are independent and usually in opposite direction to effects occurring at μM levels, suggesting that these depend on entirely different mechanisms.1 However, this does not discard the possibility ...
Isabel Larre, Marcelino Cereijido
doaj   +1 more source

Comparative analysis of the mechanokinetics of contractile activity of myometrium smooth muscles under calixarene C-99 and ouabain action

Біологічні студії, 2014
It is known that calix[4]arene with cipher C-99 selectively and with high affinity capable of inhibiting the Na+, K+-ATPase (compared with a known inhibitor of this enzyme – ouabain) of smooth muscle cells plasma membrane preparations.
O. V. Tsymbalyuk
doaj   +1 more source

Inhibition of the mitochondrial pyruvate carrier protects from excitotoxic neuronal death. [PDF]

, 2017
Glutamate is the dominant excitatory neurotransmitter in the brain, but under conditions of metabolic stress it can accumulate to excitotoxic levels.
Andreyev, Alexander Y, Bloodgood, Brenda L, Buren, Caodu, Cordes, Thekla, Divakaruni, Ajit S, Fields, Jerel A, Li, Edward, Martyniuk, Kelly, Metallo, Christian M, Murphy, Anne N, Raymond, Lynn A, Reynolds, Ian J, Wallace, Martina   +12 more
core   +1 more source

Inhibition of MMP8 effectively alleviates manic-like behavior and reduces neuroinflammation by modulating astrocytic CEBPD

Journal of Neuroinflammation
There is an intrinsic relationship between psychiatric disorders and neuroinflammation, including bipolar disorder. Ouabain, an inhibitor of Na+/K+-ATPase, has been implicated in the mouse model with manic-like behavior. However, the molecular mechanisms
Tzu-Yun Wang, Eddie Feng-Ju Weng, Yun-Chen Hsu, Lu-Ping Shiu, Teng-Wei Huang, Hsuan-Cheng Wu, Jau-Shyong Hong, Shao-Ming Wang   +7 more
doaj   +1 more source

Ouabain inhibition of Na/K-ATPase across the retina prevents signed refractive compensation to lens-induced defocus, but not default ocular growth in young chicks [v1; ref status: indexed, http://f1000r.es/rt]

F1000Research, 2013
Purpose: The relevance of retinal integrity and energy pathways to ocular growth and induction of refractive errors has seldom been investigated. Thus, we used ouabain to target the channels that are essential for the maintenance of membrane potentials ...
Melanie J Murphy, Sheila Gillard Crewther   +1 more
doaj   +1 more source

A ouabain‐sensitive membrane conductance [PDF]

The Journal of Physiology, 1968
1. Changes in membrane conductance and potential of sodium‐loaded frog muscle fibres were found when the external recovery solution was changed: from cold to warm, to warm plus ouabain, to cold plus ouabain. Comparisons of these measurements for different external solutions were made by leaving the electrodes implanted in the same fibre during all ...
openaire   +2 more sources

Na+, K+-ATPase inhibition induces neuronal cell death in rat hippocampal slice cultures: Association with GLAST and glial cell abnormalities

Journal of Pharmacological Sciences, 2018
Na+, K+-ATPase is a highly expressed membrane protein. Dysfunction of Na+, K+-ATPase has been implicated in the pathophysiology of several neurodegenerative and psychiatric disorders, however, the underlying mechanism of neuronal cell death resulting ...
Yuki Kurauchi, Kazuki Noma, Akinori Hisatsune, Takahiro Seki, Hiroshi Katsuki   +4 more
doaj   +1 more source

Role of Ca2+-activated K+ channels and Na+-K+-ATPase in prostaglandin E1- and E2-induced inhibition of the adrenergic response in human vas deferens [PDF]

, 2011
We studied the role of K+ channels and Na+,K+-ATPase in the presynaptic inhibitory effects of prostaglandin E1 (PGE1) and PGE2 on the adrenergic responses of human vas deferens.
Banchelli, Benham, Birmingham, Blatz, Brugnara, Docherty, Edwards, Galvez, Gloria Segarra, Glynn, Gordon, Hedlund, Hedqvist, Herman, Holmquist, Huang, Illes, José M. Vila, Kaczorowski, Kanwal, Legler, Liang, Malik, María Dolores Mauricio, McKay, Medina, Medina, Medina, Miller, Miller, Miller, Nakazato, North, Pascual Chuan, Pascual Medina, Ruan, Salvador Lluch, Sanbe, Scherzer, Stocker, Sturgess, Tajima, Urquilla, Webb, Winquist   +44 more
core   +3 more sources