Results 101 to 110 of about 19,639 (216)

Ouabain Effects on Human Anaplastic Thyroid Carcinoma 8505C Cells

, 2022
Anaplastic thyroid carcinoma (ATC) is a rare, but aggressive, carcinoma derived from follicular cells. While conventional treatments may improve patients’ survival, the lethality remains high.
Marcelle Novaes Andrade, de Paiva, Luciana Souza, Eliza Freitas Passos, da Silva, Joyle Moreira Carvalho, Denise Pires de Carvalho, Elizabeth Giestal-de-Araujo, Campos, Maria Luisa Arantes, Giestal-de-Araujo, Elizabeth, Maria Luisa Arantes Campos, Leandro Miranda-Alves, Teixeira, Mariana Pires, de Carvalho, Denise Pires, Natalia Ferreira Haddad, Luciana Souza de Paiva, Mariana Pires Teixeira, Camila Saggioro de Figueiredo, Miranda-Alves, Leandro, Haddad, Natalia Ferreira, Passos, Eliza Freitas, Andrade, Marcelle Novaes, Joyle Moreira Carvalho da Silva, de Figueiredo, Camila Saggioro   +21 more
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Involvement of Inflammatory Cytokines in Antiarrhythmic Effects of Clofibrate in Ouabain-Induced Arrhythmia in Isolated Rat Atria

Advances in Pharmacological Sciences, 2016
Considering the cardioprotective and anti-inflammatory properties of clofibrate, the aim of the present experiment was to investigate the involvement of local and systemic inflammatory cytokines in possible antiarrhythmic effects of clofibrate in ouabain-
Somayeh Moradi, Vahid Nikoui, Muhammad Imran Khan, Shayan Amiri, Farahnaz Jazaeri, Azam Bakhtiarian   +5 more
doaj   +1 more source

Antiapoptotic effect of ouabain on human umbilical vein endothelial cells

, 2004
The present study investigates the effect of ouabain on caspase-3 activation in human umbilical vein endothelial cells (HUVEC). Ouabain (EC(50) 20 nM) reduced caspase-3 activity in HUVEC treated for 24h in a medium deprived of fibroblast growth factor ...
TREVISI, LUCIA, CUSINATO F, VISENTIN B, PIGHIN I, LUCIANI S.   +4 more
core   +1 more source

Ouabain Counteracts Retinal Ganglion Cell Death Through Modulation of BDNF and IL-1 Signaling Pathways

Brain Sciences
Background: Ouabain is a steroid hormone that binds to the sodium pump (Na+, K+-ATPase) at physiological (nanomolar) concentrations, activating different signaling pathways.
Amanda Candida da Rocha Oliveira, Camila Saggioro Figueiredo, Ícaro Raony, Juliana Salles Von-Held-Ventura, Marcelo Gomes Granja, Thalita Mázala-de-Oliveira, Vinícius Henrique Pedrosa-Soares, Aline Araujo dos Santos, Elizabeth Giestal-de-Araujo   +8 more
doaj   +1 more source

Novel Receptors for Ouabain: Studies in Adrenocortical Cells and Membranes

, 2002
Sodium-potassium pumps (Na pumps) are the only known plasma membrane receptors for cardiac glycosides. However, adrenocortical cells secrete an endogenous ouabain via an unknown mechanism that is subject to feedback inhibition via the cell ...
Bruce P. Hamilton, John M. Hamlyn, Stephen C. Ward   +2 more
core   +1 more source

Ouabain Binding to Rabbit Erythrocytes

, 1972
iii, 29 p.Ouabain is a digitalizating cardiac glycoside. Digitalis is a drug that is administered to patients with congestive heart failure. The net effect of these cardiac glycosides are (1) a more complete systolic emptying decreasing the over all ...
Peck, Bruce F., II
core  

Ouabain modulates ciliogenesis in epithelial cells

, 2011
The exchange of substances between higher organisms and the environment occurs across transporting epithelia whose basic features are tight junctions (TJs) that seal the intercellular space, and polarity, which enables cells to transport ...
Catalina Flores-Maldonado, Ruben G. Contreras, Aida Castillo, Marcelino Cereijido, Isabel Larre, Jesus Muñoz-Estrada, Ivan Galvan   +6 more
core   +1 more source

Mechanisms of ouabain-induced arterial muscle contraction

, 1980
Ouabain caused dose-related contractions in helically cut strips of cerebral, mesenteric, renal, and femoral arteries isolated from dogs and monkeys; the contractions were elicited at lower concentrations in cerebral than in the peripheral arteries ...
N. Toda
core   +1 more source

Ouabain Binding and Cation Transport in Human Erythrocytes [PDF]

, 2020
A B S T R A C T In the present studies we have explored the relation between ouabain binding and the inhibition of potassium influx in intact human erythrocytes.
Diane R Kino, Jrmry D Gardn
core  

Ouabain - the insulin of the heart.

International journal of clinical practice, 2010
Prior to the introduction of modern drugs like angiotensin converting enzyme inhibitors and β-adrenergic receptor antagonists, the cardiac glycoside ouabain (referred to as g-Strophanthin in German) has routinely been used in treatment of heart diseases.
openaire   +2 more sources