Results 81 to 90 of about 29,310 (202)
Frontiers in Physiology, 2020 Ouabain is of cardiotonic steroids (CTS) family that is plant-derived compounds and is known for many years as therapeutic and cytotoxic agents. They are specific inhibitors of Na,K-ATPase, the enzyme, which pumps Na+ and K+ across plasma membrane of ...
Olga Dmitrievna Lopina +5 more
doaj +1 more source
Spreading depolarization and its influence on epileptiform activity
Epilepsia, Volume 67, Issue 3, Page 1078-1089, March 2026.Abstract Spreading depolarization (SD) is a transient disruption of electrographic activity that slowly propagates through the gray matter by chemical contiguity, and it is characterized by a large depolarization of neurons and glial cells. SD, which is associated with massive changes in ion homeostasis, including extreme increases in [K+]o, was shown ...
Maxime Lévesque +2 more
wiley +1 more source
The polarized expression of Na+,K+-ATPase in epithelia depends on the association between beta-subunits located in neighboring cells [PDF]
, 2005 The polarized distribution of Na+,K+-ATPase plays a paramount physiological role, because either directly or through coupling with co- and countertransporters, it is responsible for the net movement of, for example, glucose, amino acids, Ca2+, K+, Cl ...
Balda, MS +7 more
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Membrane-Mediated Alterations of Intracellular Na+ and K+ in Lytic-Virus-Infected and Retrovirus-Transformed Cells [PDF]
Infection of chick-embryo fibroblasts and other ceils by certain animal viruses results in alterations in the intracellular concentrations of Na + and K +.
Bose, Henry R. +2 more
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Construction of two whole genome radiation hybrid panels for dromedary (Camelus dromedarius): 5000RAD and 15000RAD [PDF]
, 2018 The availability of genomic resources including linkage information for camelids has been very limited. Here, we describe the construction of a set of two radiation hybrid (RH) panels (5000RAD and 15000RAD) for the dromedary (Camelus dromedarius) as a ...
Alshanbari, F +9 more
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Experimental Physiology, Volume 111, Issue 3, Page 1313-1329, 1 March 2026.Abstract The principal processes that govern interstitial K+ ([K+]o) buffering in mouse optic nerve (MON), a central white matter tract, either directly consume energy (Na+–K+‐ATPase) or use transmembrane ion gradients created by energy‐dependent pumps to enable the K+ fluxes that maintain a stable [K+]o, and thus ready availability of utilisable ...
Amy J. Hopper, Angus M. Brown
wiley +1 more source
Na+,K+-ATPase is the membrane receptor of hormone ouabain
Communicative & Integrative Biology, 2010 At 10 nM, ouabain elicits changes in cell contacts, which are independent and usually in opposite direction to effects occurring at μM levels, suggesting that these depend on entirely different mechanisms.1 However, this does not discard the possibility ...
Isabel Larre, Marcelino Cereijido
doaj +1 more source
The relevance of α-KLOTHO to the central nervous system: Some key questions [PDF]
, 2017 α-Klotho is well described as an anti-aging protein, with critical roles in kidney function as a transmembrane co-receptor for FGF23, and as a soluble factor in serum.
Berwick, Daniel Charles +4 more
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Nephroprotective effect of the cardiotonic steroid ouabain [PDF]
, 2014 It has been shown that Na,K-ATPase (NKA) is a signal transducer. Our group described the anti-apoptotic effect of ouabain to the signaling function of NKA.
Burlaka, Ievgeniia
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Біологічні студії, 2014 It is known that calix[4]arene with cipher C-99 selectively and with high affinity capable of inhibiting the Na+, K+-ATPase (compared with a known inhibitor of this enzyme – ouabain) of smooth muscle cells plasma membrane preparations.
O. V. Tsymbalyuk
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