Results 71 to 80 of about 13,484 (179)

Ouabain - the insulin of the heart.

International journal of clinical practice, 2010
Prior to the introduction of modern drugs like angiotensin converting enzyme inhibitors and β-adrenergic receptor antagonists, the cardiac glycoside ouabain (referred to as g-Strophanthin in German) has routinely been used in treatment of heart diseases.
openaire   +2 more sources

Transcriptomic changes triggered by ouabain in rat cerebellum granule cells: Role of α3- and α1-Na+,K+-ATPase-mediated signaling.

PLoS ONE, 2019
It was shown previously that inhibition of the ubiquitous α1 isoform of Na+,K+-ATPase by ouabain sharply affects gene expression profile via elevation of intracellular [Na+]i/[K+]i ratio.
Larisa V Smolyaninova, Alexandra A Shiyan, Leonid V Kapilevich, Alexander V Lopachev, Tatiana N Fedorova, Tatiana S Klementieva, Aleksey A Moskovtsev, Aslan A Kubatiev, Sergei N Orlov   +8 more
doaj   +1 more source

Protein Carbonylation of an Amino Acid Residue of the Na/K‐ATPase α1 Subunit Determines Na/K‐ATPase Signaling and Sodium Transport in Renal Proximal Tubular Cells

Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2016
Background We have demonstrated that cardiotonic steroids, such as ouabain, signaling through the Na/K‐ATPase, regulate sodium reabsorption in the renal proximal tubule.
Yanling Yan, Anna P. Shapiro, Brahma R. Mopidevi, Muhammad A. Chaudhry, Kyle Maxwell, Steven T. Haller, Christopher A. Drummond, David J. Kennedy, Jiang Tian, Deepak Malhotra, Zi‐jian Xie, Joseph I. Shapiro, Jiang Liu   +12 more
doaj   +1 more source

The Effect of Paroxetine on Ouabain-Induced Toxicity in Isolated Guinea Pig Atria [PDF]

Acta Medica Iranica, 2011
It has been reported that selective serotonin reuptake inhibitors (SSRIs) possess some cardiac effects. In the present study we have investigated the effect of paroxetine (PX), a potent SSRI agent, on spontaneously as well as ouabain-induced arrhythmia ...
Farzaneh Najar, Peyvand Bina, Sima Sabzeh-Khah, Azam Bakhtiarian, Mir-Jamal Hosseini, Abbas Pousti   +5 more
doaj  

OUABAIN

Journal of Biological Chemistry, 1933
Walter A. Jacobs, Newell M. Bigelow
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Ouabain [PDF]

Nature, 1932
openaire   +1 more source

OUABAIN

Journal of Biological Chemistry, 1936
L.F. Fieser, M.S. Newman
openaire   +1 more source

Regional Crosstalk Between the Amygdala, Hippocampus, and Prefrontal Cortex Following Na⁺,K⁺-ATPase Inhibition by Ouabain. [PDF]

Neurotox Res
Schmidt BE, Leite AKO, Farias CP, Rieder AS, Prauchner GRK, Netto CA, Wyse ATS.   +6 more
europepmc   +1 more source

Auditory perception and neural representation of temporal features are altered by age but not by cochlear synaptopathy. [PDF]

Elife
Steenken F, Beutelmann R, Oetjen H, Köppl C, Klump GM.   +4 more
europepmc   +1 more source

Ethanol disrupts cerebellar synaptic modulation by enhancing EAAT4-mediated glutamate uptake. [PDF]

Commun Biol
Satake S.
europepmc   +1 more source