Results 101 to 110 of about 29,179 (204)

Involvement of Inflammatory Cytokines in Antiarrhythmic Effects of Clofibrate in Ouabain-Induced Arrhythmia in Isolated Rat Atria

Advances in Pharmacological Sciences, 2016
Considering the cardioprotective and anti-inflammatory properties of clofibrate, the aim of the present experiment was to investigate the involvement of local and systemic inflammatory cytokines in possible antiarrhythmic effects of clofibrate in ouabain-
Somayeh Moradi, Vahid Nikoui, Muhammad Imran Khan, Shayan Amiri, Farahnaz Jazaeri, Azam Bakhtiarian   +5 more
doaj   +1 more source

Potassium ion influx and Na+,K+-ATPase activity are required for the hamster sperm acrosome reaction. [PDF]

, 1981
The role of a K+ ion influx and Na+,K+-ATPase activity in the hamster sperm acrosome reaction (AR) was examined, using a range of concentrations of K+,K+ ionophores and a Na+,K+-ATPase inhibitor.
Meizel, S, Mrsny, RJ
core  

Ouabain Counteracts Retinal Ganglion Cell Death Through Modulation of BDNF and IL-1 Signaling Pathways

Brain Sciences
Background: Ouabain is a steroid hormone that binds to the sodium pump (Na+, K+-ATPase) at physiological (nanomolar) concentrations, activating different signaling pathways.
Amanda Candida da Rocha Oliveira, Camila Saggioro Figueiredo, Ícaro Raony, Juliana Salles Von-Held-Ventura, Marcelo Gomes Granja, Thalita Mázala-de-Oliveira, Vinícius Henrique Pedrosa-Soares, Aline Araujo dos Santos, Elizabeth Giestal-de-Araujo   +8 more
doaj   +1 more source

Effects of Age on Na+,K+-ATPase Expression in Human and Rodent Skeletal Muscle [PDF]

, 2016
The maintenance of transmembrane Na+ and K+ concentration gradients and membrane potential is vital for the production of force in skeletal muscle. In ageing an inability to maintain ion regulation and membrane potential would have adverse consequences ...
McKenna, Michael, Wyckelsma, Victoria
core   +2 more sources

Transcriptomic changes triggered by ouabain in rat cerebellum granule cells: Role of α3- and α1-Na+,K+-ATPase-mediated signaling.

PLoS ONE, 2019
It was shown previously that inhibition of the ubiquitous α1 isoform of Na+,K+-ATPase by ouabain sharply affects gene expression profile via elevation of intracellular [Na+]i/[K+]i ratio.
Larisa V Smolyaninova, Alexandra A Shiyan, Leonid V Kapilevich, Alexander V Lopachev, Tatiana N Fedorova, Tatiana S Klementieva, Aleksey A Moskovtsev, Aslan A Kubatiev, Sergei N Orlov   +8 more
doaj   +1 more source

Protein Carbonylation of an Amino Acid Residue of the Na/K‐ATPase α1 Subunit Determines Na/K‐ATPase Signaling and Sodium Transport in Renal Proximal Tubular Cells

Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2016
Background We have demonstrated that cardiotonic steroids, such as ouabain, signaling through the Na/K‐ATPase, regulate sodium reabsorption in the renal proximal tubule.
Yanling Yan, Anna P. Shapiro, Brahma R. Mopidevi, Muhammad A. Chaudhry, Kyle Maxwell, Steven T. Haller, Christopher A. Drummond, David J. Kennedy, Jiang Tian, Deepak Malhotra, Zi‐jian Xie, Joseph I. Shapiro, Jiang Liu   +12 more
doaj   +1 more source

The Effect of Paroxetine on Ouabain-Induced Toxicity in Isolated Guinea Pig Atria [PDF]

Acta Medica Iranica, 2011
It has been reported that selective serotonin reuptake inhibitors (SSRIs) possess some cardiac effects. In the present study we have investigated the effect of paroxetine (PX), a potent SSRI agent, on spontaneously as well as ouabain-induced arrhythmia ...
Farzaneh Najar, Peyvand Bina, Sima Sabzeh-Khah, Azam Bakhtiarian, Mir-Jamal Hosseini, Abbas Pousti   +5 more
doaj  

Cardiac glycoside binding sites in cultured heart muscle cells [PDF]

, 1984
Erdmann, E., Krawietz, W., Wagenknecht, B., Werdan, K., Zwißler, Bernhard   +4 more
core   +1 more source

Regulation of blood pressure during long-term ouabain infusion in Long-Evans rats [PDF]

, 2017
We tested whether ouabain, an inhibitor of the sodium pump, can lead to chronic hypertension in Long-Evans rats using sensitive 24-h measurements of blood pressure.
Montani, Jean-Pierre, Schnyder, Bruno, Tempini, Aldo, Wang, Jingli   +3 more
core  

Cardiac glycoside receptors in cultured heart cells II [PDF]

, 1984
Brown, L., Erdmann, E., Krawietz, W., Wagenknecht, B., Werdan, K., Zwißler, Bernhard   +5 more
core   +2 more sources