Results 61 to 70 of about 18,820 (207)

Vanillin Enhances Photobiomodulation Wound Healing by Modulating Glyco‐Oxidative Stress and Glucose Dysmetabolism in Diabetic Wounded Fibroblast Cells

open access: yesJournal of Cellular and Molecular Medicine, Volume 29, Issue 7, April 2025.
ABSTRACT Delayed wound healing is among the major peripheral complications of diabetes. Synergistic treatment of diabetic wounds (DW) with phytochemicals and non‐invasive techniques has shown promising results. The synergistic effect of vanillin and photobiomodulation (PBM) on DW healing, and their modulatory effect on oxidative stress and glucose ...
Ochuko L. Erukainure   +1 more
wiley   +1 more source

Involvement of the Na+/Ca2+ Exchanger in Ouabain-Induced Inotropy and Arrhythmogenesis in Guinea-Pig Myocardium as Revealed by SEA0400

open access: yesJournal of Pharmacological Sciences, 2007
Involvement of the Na+/Ca2+ exchanger in ouabain-induced inotropy and arrhythmogenesis was examined with a specific inhibitor, SEA0400. In right ventricular papillary muscle isolated from guinea-pig ventricle, 1 µM SEA0400, which specifically inhibits ...
Hikaru Tanaka   +5 more
doaj  

A ouabain‐sensitive membrane conductance [PDF]

open access: yesThe Journal of Physiology, 1968
1. Changes in membrane conductance and potential of sodium‐loaded frog muscle fibres were found when the external recovery solution was changed: from cold to warm, to warm plus ouabain, to cold plus ouabain. Comparisons of these measurements for different external solutions were made by leaving the electrodes implanted in the same fibre during all ...
openaire   +3 more sources

Na+,K+-ATPase is the membrane receptor of hormone ouabain

open access: yesCommunicative & Integrative Biology, 2010
At 10 nM, ouabain elicits changes in cell contacts, which are independent and usually in opposite direction to effects occurring at μM levels, suggesting that these depend on entirely different mechanisms.1 However, this does not discard the possibility ...
Isabel Larre, Marcelino Cereijido
doaj   +1 more source

Computational Drug Repositioning in Cardiorenal Disease: Opportunities, Challenges, and Approaches

open access: yes
PROTEOMICS, EarlyView.
Paul Perco   +7 more
wiley   +1 more source

Role of the calcium‐sensing receptor in regulating vascular function

open access: yesJournal of Cell Communication and Signaling, Volume 19, Issue 1, March 2025.
Representation of the role of the CaSR in the vasculature shows that a rise in extracellular Ca2+ concentration ([Ca2+]o) stimulates the CaSR expressed at the plasma membrane of perivascular sensory nerves, VECs, and VSMCs, which leads to the release of vasodilator substances (e.g., calcitonin‐related gene‐related peptide (CGRP), substance P (Sub P ...
Anthony P. Albert, Harry Z.E. Greenberg
wiley   +1 more source

A Comprehensive Analysis of Epoxide Hydrolase 2 (EPHX2) in Pan‐Cancer

open access: yesCancer Reports, Volume 8, Issue 3, March 2025.
ABSTRACT Background and Aims Epoxide hydrolase 2 (EPHX2) regulates lipid signaling across various metabolites by encoding soluble epoxide hydrolase. However, its mechanisms and implications in human malignancies remain unknown. This research aimed to detail the prognostic landscape of EPHX2 in pan‐cancer and explore its potential relationship with ...
Weiquan Hu   +9 more
wiley   +1 more source

Comparative analysis of the mechanokinetics of contractile activity of myometrium smooth muscles under calixarene C-99 and ouabain action

open access: yesБіологічні студії, 2014
It is known that calix[4]arene with cipher C-99 selectively and with high affinity capable of inhibiting the Na+, K+-ATPase (compared with a known inhibitor of this enzyme – ouabain) of smooth muscle cells plasma membrane preparations.
O. V. Tsymbalyuk
doaj   +1 more source

The Na+,K+,2Cl− Cotransporter, Not Aquaporin 1, Sustains Cerebrospinal Fluid Secretion While Controlling Brain K+ Homeostasis

open access: yesAdvanced Science, Volume 12, Issue 6, February 10, 2025.
CSF is secreted by the choroid plexus in each ventricle. The choroid plexus water channel, aquaporin 1, is not required for CSF secretion and thus brain fluid dynamics, whereas the Na+, K+, 2Cl‐ cotransporter 1 is a key factor in this process. Elevated ventricular K+ alters the transport activity to clear brain K+ while maintaining the CSF secretion ...
Dennis Bo Jensen   +12 more
wiley   +1 more source

Ouabain inhibition of Na/K-ATPase across the retina prevents signed refractive compensation to lens-induced defocus, but not default ocular growth in young chicks [v1; ref status: indexed, http://f1000r.es/rt]

open access: yesF1000Research, 2013
Purpose: The relevance of retinal integrity and energy pathways to ocular growth and induction of refractive errors has seldom been investigated. Thus, we used ouabain to target the channels that are essential for the maintenance of membrane potentials ...
Melanie J Murphy   +1 more
doaj   +1 more source

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