Results 41 to 50 of about 29,553 (224)
Changes in extracellular pH during electrical stimulation of isolated rat vagus nerve [PDF]
, 1986 Double-barrelled pH-sensitive micro-electrodes were used to record changes of extracellular pH during repetitive stimulation of isolated rat vagus nerves. It was found that a small initial alkaline shift was followed by a prolonged acidification.
Ammann +16 more
core +1 more source
Discover Oncology, 2023 Background Glioblastoma multiforme (GBM) is the most aggressive primary brain tumor with poor prognosis. GMB are highly recurrent mainly because of radio- and chemoresistance.
Heidrun Weidemann +4 more
doaj +1 more source
Cellular mechanisms of potassium homeostasis in the mammalian nervous system [PDF]
, 1987 Double-barrelled ion-sensitive microelectrodes were used to measure changes in the intracellular activities of K+, Na+, and Cl- (aKi, aNai, aCli) in neurones of rat sympathetic ganglia and in glial cells of slices from guinea-pig olfactory cortex.
Ballanyi, Klaus, Grafe, Peter
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Neuroinflammation and Neutrophils: Modulation by Ouabain [PDF]
Frontiers in Pharmacology, 2022 Cardiotonic steroids are natural compounds that present many physiological and pharmacological functions. They bind Na+/K+-ATPase (NKA) modifying cellular ion concentration and trigger cell signaling mechanisms without altering ion balance. These steroids are known to modulate some immune responses, including cytokine production, neutrophil migration ...
Jacqueline Alves Leite +5 more
openaire +3 more sources
Changes in intracellular ion activities induced by adrenaline in human and rat skeletal muscle [PDF]
, 1988 To study the stimulating effect of adrenaline (ADR) on active Na+/K+ transport we used double-barrelled ion-sensitive micro-electrodes to measure the activities of extracellular K+ (aKe) and intracellular Na+ (aNai) in isolated preparations of rat soleus
A Chinet +29 more
core +1 more source
Ouabain enhances ADPKD cell apoptosis via the intrinsic pathway
Frontiers in Physiology, 2016 Progression of autosomal dominant polycystic kidney disease (ADPKD) is highly influenced by factors circulating in blood. We have shown that the hormone ouabain enhances several characteristics of the ADPKD cystic phenotype, including the rate of cell ...
Gustavo eBlanco, Jessica eVenugopal
doaj +1 more source
Sodium chloride transport of normal and dietary enlarged rat cecum in vitro [PDF]
, 1998 Sodium chloride transport across isolated cecum mucosa was investigated in normal rats and rats with adaptive cecum growth induced by dietary polyethylene glycol (PEG). The normal cecum absorbed CI in excess of Na with a small short-circuit current (Isc).
Loeschke, Klaus +2 more
core +1 more source
Radioiodinated Tyrosyl-Ouabain and Measurement of a Circulating Ouabain-like Compound [PDF]
Clinical Chemistry, 2001 Abstract Background: Assays for endogenous ouabain, a cardiac glycoside believed to be involved in blood pressure and volume regulation, are characterized by laboratory-specific plasma values that are measured by different assays. Because of this variability, our study focused on the development of a new 125I-labeled ouabain derivative ...
O, Vakkuri +5 more
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THE EFFECT OF LITHIUM ON THE INOTROPIC EFFECT OF OUABAIN AND MANIFESTATION OF ARRHYTHMIA IN GUINEA-PIG ATRIA [PDF]
Acta Medica Iranica, 1995 rli....xposure ofthe guinea-pig whole a/ria to lithium (1 and 5 mM) produced a reduction ofinotropic response to ouubain. The inhibitory effect oflithium (1 m"f) was slight, whereas lithium (5 mM) significantly reduced tlze response oj the preparations ...
Ahmad Reza Dehpour +3 more
doaj +2 more sources
Frontiers in Physiology, 2020 The cardiotonic steroids (CTS), such as ouabain and marinobufagenin, are thought to be adrenocortical hormones secreted during exercise and the stress response. The catalytic α-subunit of Na,K-ATPase (NKA) is a CTS receptor, whose largest pool is located
Sergej Pirkmajer +13 more
doaj +1 more source