Results 71 to 80 of about 18,820 (207)
Is Ouabain Produced by the Adrenal Gland?
General Pharmacology: The Vascular System, 1998 1. Ouabain or a related stereoisomer, termed endogenous ouabain, has been identified in adrenal cortex tissue and culture medium from adrenocortical cells. 2. Angiotensin II and adrenocorticotropin, the main activators of aldosterone secretion from adrenal glomerulosa cells appear to increase the production of this compound. 3.
Foster, Richard H. +2 more
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Clinical and Translational Medicine, Volume 15, Issue 2, February 2025.• NKAα1 downregulation impairs endothelial function in diabetes by promoting oxidative/nitrative stress and ferroptosis. • NKAα1 supports lysosomal degradation of ACSL4 via autophagy, preventing lipid peroxidation and ferroptosis. • Hamaudol, an activator of NKAα1, restores endothelial relaxation in diabetic mice by inhibiting NKAα1 phosphorylation and
Xue‐Xue Zhu +16 more
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Toxicity of ouabain on Drosophila melanogaster
Experientia, 1977 Uploaded by Plazi for TaxoDros. We do not have abstracts.
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Advances in Pharmacological Sciences, 2016 Considering the cardioprotective and anti-inflammatory properties of clofibrate, the aim of the present experiment was to investigate the involvement of local and systemic inflammatory cytokines in possible antiarrhythmic effects of clofibrate in ouabain-
Somayeh Moradi +5 more
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PRODUCTION AND CHARACTERIZATION OF ANTIBODIES TO OUABAIN
Japanese Journal of Medical Science and Biology, 1991 Two monoclonal antibodies (249F8 and 278A9) to ouabain were produced by somatic cell fusion. They reacted in dose-dependent manners with ouabain and digoxin. These antibodies were supposed to recognize the partial structure important for cardiac compounds to show their pharmacological activity, Na+, K(+)-ATPase inhibition in a competitive mode against ...
Yoshitake Terano +2 more
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The Effect of Paroxetine on Ouabain-Induced Toxicity in Isolated Guinea Pig Atria [PDF]
Acta Medica Iranica, 2011 It has been reported that selective serotonin reuptake inhibitors (SSRIs) possess some cardiac effects. In the present study we have investigated the effect of paroxetine (PX), a potent SSRI agent, on spontaneously as well as ouabain-induced arrhythmia ...
Farzaneh Najar +5 more
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PLoS ONE, 2019 It was shown previously that inhibition of the ubiquitous α1 isoform of Na+,K+-ATPase by ouabain sharply affects gene expression profile via elevation of intracellular [Na+]i/[K+]i ratio.
Larisa V Smolyaninova +8 more
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Effect of Hypoadrenalism and Excessive Doses of Desoxycorticosterone Acetate upon Response of the Rat to Ouabain [PDF]
, 1955 David Unterman +2 more
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The Effect of Diphenylhydantoin Sodium (Dilantin), Procaine Hydrochloride, Procaine Amide Hydrochloride, and Quinidine Hydrochloride upon Ouabain-Induced Ventricular Tachycardia in Unanesthetized Dogs [PDF]
, 1954 Lois M. Mosey, Myra D. Tyler
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