Results 71 to 80 of about 18,941 (209)

Toxicity of ouabain on Drosophila melanogaster

Experientia, 1977
Uploaded by Plazi for TaxoDros. We do not have abstracts.
openaire   +4 more sources

Involvement of Inflammatory Cytokines in Antiarrhythmic Effects of Clofibrate in Ouabain-Induced Arrhythmia in Isolated Rat Atria

Advances in Pharmacological Sciences, 2016
Considering the cardioprotective and anti-inflammatory properties of clofibrate, the aim of the present experiment was to investigate the involvement of local and systemic inflammatory cytokines in possible antiarrhythmic effects of clofibrate in ouabain-
Somayeh Moradi, Vahid Nikoui, Muhammad Imran Khan, Shayan Amiri, Farahnaz Jazaeri, Azam Bakhtiarian   +5 more
doaj   +1 more source

Ouabain alleviates Mycobacterium abscessus-triggered inflammatory responses through dual regulation of NLRP3 inflammasome activity and M1 macrophage polarization

Frontiers in Immunology
IntroductionMycobacterium abscessus (M. abscessus) is a highly drug-resistant pathogen responsible for chronic pulmonary inflammation in humans. The cardiac glycoside ouabain exhibits broad anti-inflammatory effects in various disease models, but its ...
Nan Li, Nan Li, Nan Li, Songqiang Huang, Songqiang Huang, Xing Shi, Kuo Lu, Kuo Lu, Xiu Yu, Chen Qiu, Rongchang Chen   +10 more
doaj   +1 more source

The Effect of Diphenylhydantoin Sodium (Dilantin), Procaine Hydrochloride, Procaine Amide Hydrochloride, and Quinidine Hydrochloride upon Ouabain-Induced Ventricular Tachycardia in Unanesthetized Dogs [PDF]

, 1954
Lois M. Mosey, Myra D. Tyler
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PRODUCTION AND CHARACTERIZATION OF ANTIBODIES TO OUABAIN

Japanese Journal of Medical Science and Biology, 1991
Two monoclonal antibodies (249F8 and 278A9) to ouabain were produced by somatic cell fusion. They reacted in dose-dependent manners with ouabain and digoxin. These antibodies were supposed to recognize the partial structure important for cardiac compounds to show their pharmacological activity, Na+, K(+)-ATPase inhibition in a competitive mode against ...
Yoshitake Terano, Akiko Tomii, Fuminori Masugi   +2 more
openaire   +4 more sources

Computational Drug Repositioning in Cardiorenal Disease: Opportunities, Challenges, and Approaches

PROTEOMICS, Volume 25, Issue 11-12, June 2025.
Paul Perco, Matthias Ley, Kinga Kęska‐Izworska, Dorota Wojenska, Enrico Bono, Samuel M. Walter, Lucas Fillinger, Klaus Kratochwill   +7 more
wiley   +1 more source

Mechanistic insight into the initiation of spreading depolarizations: Is it really all about potassium?

The Journal of Physiology, Volume 603, Issue 11, Page 3269-3273, 1 June 2025.
Rachel Ricks, Connie MacKenzie‐Gray Scott, Andrew J. Trevelyan, R. Ryley Parrish   +3 more
wiley   +1 more source

The Effect of Paroxetine on Ouabain-Induced Toxicity in Isolated Guinea Pig Atria [PDF]

Acta Medica Iranica, 2011
It has been reported that selective serotonin reuptake inhibitors (SSRIs) possess some cardiac effects. In the present study we have investigated the effect of paroxetine (PX), a potent SSRI agent, on spontaneously as well as ouabain-induced arrhythmia ...
Farzaneh Najar, Peyvand Bina, Sima Sabzeh-Khah, Azam Bakhtiarian, Mir-Jamal Hosseini, Abbas Pousti   +5 more
doaj   +2 more sources

Transcriptomic changes triggered by ouabain in rat cerebellum granule cells: Role of α3- and α1-Na+,K+-ATPase-mediated signaling.

PLoS ONE, 2019
It was shown previously that inhibition of the ubiquitous α1 isoform of Na+,K+-ATPase by ouabain sharply affects gene expression profile via elevation of intracellular [Na+]i/[K+]i ratio.
Larisa V Smolyaninova, Alexandra A Shiyan, Leonid V Kapilevich, Alexander V Lopachev, Tatiana N Fedorova, Tatiana S Klementieva, Aleksey A Moskovtsev, Aslan A Kubatiev, Sergei N Orlov   +8 more
doaj   +1 more source

Effect of Hypoadrenalism and Excessive Doses of Desoxycorticosterone Acetate upon Response of the Rat to Ouabain [PDF]

, 1955
David Unterman, Arthur C. DeGraff, Herbert S. Kupperman   +2 more
openalex   +1 more source