Results 81 to 90 of about 37,475 (253)

Extinction of tyrosine aminotransferase gene activity in somatic cell hybrids involves modification and loss of several essential transcription factors [PDF]

open access: yes, 1993
Extinction is defined as the loss of cell type-specific gene expression that occurs in somatic cell hybrids derived by fusion of cells with dissimilar phenotypes.
Boshart, Michael   +2 more
core   +1 more source

Nerol Attenuates Ouabain-Induced Arrhythmias [PDF]

open access: yesEvidence-Based Complementary and Alternative Medicine, 2019
Nerol (C10H18O) is a monoterpene found in many essential oils, such as lemon balm and hop. In this study, we explored the contractile and electrophysiological properties of nerol and demonstrated its antiarrhythmic effects in guinea pig heart preparation.
José Evaldo Rodrigues de Menezes-Filho   +7 more
openaire   +2 more sources

Non‐Invasive, High‐Resolution (1H2O) Metabolic Activity Diffusion Imaging [MADI] of Rat Glioma

open access: yesNMR in Biomedicine, Volume 39, Issue 3, March 2026.
We employed Metabolic Activity Diffusion Imaging [MADI] and 18FDG‐PET in rats with syngeneic RG2 glioblastoma brain tumors. MADI quantifies kio (the cellular H2O efflux rate constant), cell volume (V), and cell density (ρ), without the use of contrast agents. The kioV product quantifies the rate of water efflux per cell.
Joshua W. Schlegel   +9 more
wiley   +1 more source

Cardiac glycoside ouabain efficiently targets leukemic stem cell apoptotic machinery independent of cell differentiation status

open access: yesCell Communication and Signaling, 2023
Background Acute myeloid leukemia (AML) is an aggressive hematologic malignancy characterized by an accumulation of immature leukemic myeloblasts initiating from leukemic stem cells (LSCs)—the subpopulation that is also considered the root cause of ...
Jirarat Poohadsuan   +6 more
doaj   +1 more source

Inhibition of activity of GABA transporter GAT1 by δ-opioid receptor [PDF]

open access: yes, 2012
Analgesia is a well-documented effect of acupuncture. A critical role in pain sensation plays the nervous system, including the GABAergic system and opioid receptor (OR) activation.
Fucke, Thomas   +7 more
core   +2 more sources

Cryopreserved Human Otic Neuronal Spheroids Self‐assemble for Functional Connectivity Analysis and Long‐term Ototoxicity Evaluation

open access: yesAdvanced Science, Volume 13, Issue 7, 3 February 2026.
This study establishes a robust and reproducible protocol for generating human otic neuronal spheroids (hONS) from cryopreserved hPSC‐derived pre‐placodal ectoderm cells. These hONS further differentiate into functional SGN‐like neurons, which extend neurite projections toward both murine hair cells and human cortical organoids, thereby forming ...
Gaoying Sun   +15 more
wiley   +1 more source

The polarized expression of Na+,K+-ATPase in epithelia depends on the association between beta-subunits located in neighboring cells [PDF]

open access: yes, 2005
The polarized distribution of Na+,K+-ATPase plays a paramount physiological role, because either directly or through coupling with co- and countertransporters, it is responsible for the net movement of, for example, glucose, amino acids, Ca2+, K+, Cl ...
Balda, MS   +7 more
core  

Body Biofluids for Minimally‐Invasive Diagnostics: Insights, Challenges, Emerging Technologies, and Clinical Potential

open access: yesAdvanced Healthcare Materials, Volume 15, Issue 4, 26 January 2026.
Recent advances in diagnostics have accelerated the development of miniaturized wearable technologies for the continuous monitoring of diseases. This paradigm is shifting healthcare away from invasive, centralized blood tests toward decentralized monitoring, using alternative body biofluids.
Lanka Tata Rao   +2 more
wiley   +1 more source

Activation of electroneutral K flux in Amphiuma red blood cells by N-ethylmaleimide. Distinction between K/H exchange and KCl cotransport. [PDF]

open access: yes, 1987
Exposure of Amphiuma red blood cells to millimolar concentrations of N-ethylmaleimide (NEM) resulted in net K loss. In order to determine whether net K loss was conductive or was by electroneutral K/H exchange or KCl cotransport, studies were performed ...
Adorante, JS, Cala, PM
core  

Changes in extracellular pH during electrical stimulation of isolated rat vagus nerve [PDF]

open access: yes, 1986
Double-barrelled pH-sensitive micro-electrodes were used to record changes of extracellular pH during repetitive stimulation of isolated rat vagus nerves. It was found that a small initial alkaline shift was followed by a prolonged acidification.
Ammann   +16 more
core   +1 more source

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