Results 91 to 100 of about 3,725,551 (310)

Construct domain analysis of patient health-related quality of life: physical and mental trajectory profiles following open versus endovascular repair of abdominal aortic aneurysm

open access: yesPatient Related Outcome Measures, 2012
Nicolas J Mouawad, Stefan W Leichtle, Jeffrey V Manchio, Richard M Lampman, Brian G Halloran, Walter M Whitehouse JrMichigan Heart and Vascular Institute, Saint Joseph Mercy Health System, Ann Arbor, MI, USAPurpose: Many clinical trials comparing the ...
Mouawad NJ   +5 more
doaj  

Interplay between circadian and other transcription factors—Implications for cycling transcriptome reprogramming

open access: yesFEBS Letters, EarlyView.
This perspective highlights emerging insights into how the circadian transcription factor CLOCK:BMAL1 regulates chromatin architecture, cooperates with other transcription factors, and coordinates enhancer dynamics. We propose an updated framework for how circadian transcription factors operate within dynamic and multifactorial chromatin landscapes ...
Xinyu Y. Nie, Jerome S. Menet
wiley   +1 more source

Effectiveness of a physiotherapy-initiated telephone triage of orthopedic waitlist patients

open access: yesPatient Related Outcome Measures, 2011
Joanne Morris1, Karen Grimmer-Somers2, Saravana Kumar2, Karen Murphy3, Lisa Gilmore1, Bryan Ashman1, Chandima Perera1, Kathryn Vine1, Corinne Coulter11The Canberra Hospital, ACT Government Health Directorate, Canberra, ACT, Australia; 2International ...
Gilmore L   +8 more
doaj  

Patient-Reported Outcomes in Rheumatoid Arthritis: A Key Consideration for Evaluating Biosimilar Uptake?

open access: yesPatient Related Outcome Measures, 2022
Gabriel Horta-Baas Rheumatology Department, Hospital General Regional # 1, Instituto Mexicano del Seguro Social, Merida, Yucatan, MexicoCorrespondence: Gabriel Horta-Baas, Rheumatology Department, Hospital General Regional # 1, Instituto Mexicano del ...
Horta-Baas G
doaj  

Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing

open access: yesFEBS Letters, EarlyView.
Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley   +1 more source

Provider use of a participatory decision-making style with youth and caregivers and satisfaction with pediatric asthma visits

open access: yesPatient Related Outcome Measures, 2018
Betsy Sleath,1,2 Delesha M Carpenter,1 Imelda Coyne,3 Scott A Davis,1 Claire Hayes Watson,1 Ceila E Loughlin,4 Nacire Garcia,1 Daniel S Reuland,5 Gail E Tudor6 1Division of Pharmaceutical Outcomes and Policy, UNC Eshelman School of Pharmacy, University ...
Sleath B   +8 more
doaj  

Antiepileptic Drug Treatment Outcomes and Seizure-Related Injuries Among Adult Patients with Epilepsy in a Tertiary Care Hospital in Ethiopia

open access: yesPatient Related Outcome Measures, 2020
Beshir Bedru Nasir,1 Yared Mamushet Yifru,2 Ephrem Engidawork,1 Meron Awraris Gebrewold,2 Minyahil Alebachew Woldu,1 Alemseged Beyene Berha1 1Department of Pharmacology and Clinical Pharmacy, School of Pharmacy, College of Health Sciences, Addis Ababa ...
Nasir BB   +5 more
doaj  

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

open access: yesFEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe   +3 more
wiley   +1 more source

National Institutes of Health Toolbox Emotion Battery for English- and Spanish-speaking adults: normative data and factor-based summary scores

open access: yesPatient Related Outcome Measures, 2018
Ida Babakhanyan,1,2 Benjamin S McKenna,2 Kaitlin B Casaletto,3 Cindy J Nowinski,4 Robert K Heaton2 1Defense and Veteran’s Brain Injury Center, Camp Pendleton, 2Department of Psychiatry, University of California, San Diego, La Jolla, 3Department of ...
Babakhanyan I   +4 more
doaj  

Function‐driven design of a surrogate interleukin‐2 receptor ligand

open access: yesFEBS Letters, EarlyView.
Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang   +9 more
wiley   +1 more source

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