Results 31 to 40 of about 16,988,510 (382)

The effect of delaying initiation with umeclidinium/vilanterol in patients with COPD: an observational administrative claims database analysis using marginal structural models

Multidisciplinary Respiratory Medicine, 2018
Background Chronic obstructive pulmonary disease (COPD) is associated with high clinical and economic burden. Optimal pharmacological therapy for COPD aims to reduce symptoms and the frequency and severity of exacerbations.
Ami R. Buikema, Lee Brekke, Amy Anderson, Eleena Koep, Damon Van Voorhis, Lucie Sharpsten, Beth Hahn, Riju Ray, Richard H. Stanford   +8 more
doaj   +1 more source

Development of a novel patient-reported outcome measure to assess signs and symptoms of COVID-19

Journal of Patient-Reported Outcomes, 2022
Background Given the urgent need for vaccines and treatments for coronavirus disease 2019 (COVID-19), the Symptoms of Infection with Coronavirus-19 (SIC), a comprehensive, patient-reported outcome (PRO) measure of signs and symptoms associated with COVID-
Carla Romano, Sheri Fehnel, Jeffrey Stoddard, Jerald Sadoff, Sandy Lewis, Pauline McNulty, Eric K. H. Chan, Emily Evans, Carol Jamieson, Ashley F. Slagle, Allen Mangel, Kelly McQuarrie   +11 more
doaj   +1 more source

Holmium Laser Enucleation of the Prostate [PDF]

, 2018
Introduction: Holmium laser enucleation of the prostate (HoLEP) offers superior voiding outcomes to traditional transurethral resection and less morbidity than open simple prostatectomy. Likewise, HoLEP has been determined to result in excellent outcomes
Krambeck, Amy E., Lingeman, James E., Rivera, Marcelino E.   +2 more
core   +1 more source

Observational vignette study to examine patient and healthcare provider perceived impact of asthma-related exacerbations in the US

Multidisciplinary Respiratory Medicine, 2019
Background Little is known about how patients and healthcare providers (HCPs) perceive the impact of asthma-related exacerbations. This study examined the impact of asthma-related exacerbations on patients’ lives from these different perspectives ...
Phaedra T. Johnson, Christopher F. Bell, John White, Breanna Essoi, Linda Nelsen, Carlyne M. Averell   +5 more
doaj   +1 more source

Effect of Finerenone on Chronic Kidney Disease Outcomes in Type 2 Diabetes.

New England Journal of Medicine, 2020
BACKGROUND Finerenone, a nonsteroidal, selective mineralocorticoid receptor antagonist, reduced albuminuria in short-term trials involving patients with chronic kidney disease (CKD) and type 2 diabetes.
G. Bakris, R. Agarwal, S. Anker, B. Pitt, L. Ruilope, P. Rossing, P. Kolkhof, C. Nowack, Patrick Schloemer, A. Joseph, G. Filippatos   +10 more
semanticscholar   +1 more source

Costs, outcomes, and cost-effectiveness of ovc interventions [PDF]

, 2010
This item is archived in the repository for materials published for the USAID supported Orphans and Vulnerable Children Comprehensive Action Research Project (OVC-CARE) at the Boston University Center for Global Health and Development.More than 1 out of ...
Larson, Bruce
core   +1 more source

Qualitative research to explore the symptoms and impacts experienced by children with ulcerative colitis

Journal of Patient-Reported Outcomes, 2020
Background Ulcerative Colitis (UC) is a chronic gastrointestinal disease that often presents during one’s most productive years and is characterized by colon inflammation.
Jason A. Randall, Aiste Guobyte, Laure Delbecque, Louise Newton, Tara Symonds, Theresa Hunter   +5 more
doaj   +1 more source

Key measurement concepts and appropriate clinical outcome assessments in pediatric achondroplasia clinical trials

Orphanet Journal of Rare Diseases, 2022
Background This study aimed to identify fit-for-purpose clinical outcome assessments (COAs) to evaluate physical function, as well as social and emotional well-being in clinical trials enrolling a pediatric population with achondroplasia.
Natalie V. J. Aldhouse, Helen Kitchen, Chloe Johnson, Chris Marshall, Hannah Pegram, Sheryl Pease, Sam Collins, Christine L. Baker, Katherine Beaverson, Chandler Crews, Jill Massey, Kathleen W. Wyrwich   +11 more
doaj   +1 more source

Outcomes and outcome measures

Haemophilia
AbstractIntroductionAdvances in haemophilia treatment have resulted in a near‐normal life expectancy, lower burden of bleeding and treatment, and improved quality of life in high‐income countries. Bleeding rate is approaching zero and novel parameters should be evaluated to assess the efficacy of treatment not only from the clinical point of view by ...
Giancarlo Castaman, Victor Jimenez‐Yuste, Samanta Gouw, Roseline D'Oiron   +3 more
openaire   +2 more sources

Treatment Effects on Ordinal Outcomes: Causal Estimands and Sharp Bounds

, 2018
Assessing the causal effects of interventions on ordinal outcomes is an important objective of many educational and behavioral studies. Under the potential outcomes framework, we can define causal effects as comparisons between the potential outcomes ...
Dasgupta, Tirthankar, Ding, Peng, Lu, Jiannan   +2 more
core   +1 more source