Results 31 to 40 of about 4,586,853 (323)
Validation of the 5-domain Niemann-Pick type C Clinical Severity Scale
Orphanet Journal of Rare Diseases, 2021 Background Niemann-Pick disease type C (NPC) is an ultra-rare, progressive, genetic disease leading to impaired lysosomal function and neurodegeneration causing serious morbidity and shortened life expectancy.
Marc C. Patterson +8 more
doaj +1 more source
Using Multiple Outcomes to Improve the Synthetic Control Method [PDF]
arXiv, 2023 When there are multiple outcome series of interest, Synthetic Control analyses typically proceed by estimating separate weights for each outcome. In this paper, we instead propose estimating a common set of weights across outcomes, by balancing either a vector of all outcomes or an index or average of them.
arxiv
Clinical Prediction Models to Predict the Risk of Multiple Binary Outcomes: a comparison of approaches [PDF]
, 2020 Clinical prediction models (CPMs) are used to predict clinically relevant outcomes or events. Typically, prognostic CPMs are derived to predict the risk of a single future outcome. However, with rising emphasis on the prediction of multi-morbidity, there is growing need for CPMs to simultaneously predict risks for each of multiple future outcomes.
arxiv +1 more source
Journal of Patient-Reported OutcomesBackground Goal attainment scaling (GAS), an established individualized, patient-centred outcome measure, is used to capture the patient’s voice. Although first introduced ~60 years ago, there are few published guidelines for implementing GAS, and almost
Kulpreet Cheema +5 more
doaj +1 more source
Facial Plastic Surgery, 2019 AbstractIn recent years, there is an increasing trend to use health-related quality of life questionnaires after surgical procedures. The idea is to prove the success of an operation by objectively measurable parameters. Rhinoplasty is by far the most frequently performed surgery of facial plastic surgery. One of the most difficult parts of rhinoplasty
Beegun, Issa +2 more
openaire +4 more sources
Significance, 2015 Abstract Gianluca Baio and Roberto Cerina used a modified version of a dynamic Bayesian forecasting model to “predict” the 2014 US Senate elections.
Baio, G, Cerina, R
openaire +3 more sources
The dual nature of TDC – bridging dendritic and T cells in immunity
FEBS Letters, EarlyView.TDC are hematopoietic cells combining dendritic and T cell features. They reach secondary lymphoid organs (SLOs) and peripheral organs (liver and lungs) after FLT3‐dependent development in the bone marrow and maturation in the thymus. TDC are activated and enriched in SLOs upon viral infection, suggesting that they might play unique immune roles, since
Maria Nelli, Mirela Kuka
wiley +1 more source
Journal of Patient-Reported Outcomes, 2021 Background Presbyopia is a progressive condition that reduces the eye’s ability to focus on near objects with increasing age. After a systematic literature review identified no existing presbyopia-specific patient-reported outcome (PRO) instruments ...
Elaheh Shirneshan +8 more
doaj +1 more source
FEBS Letters, EarlyView.In vivo IL‐10 produced by tissue‐resident tolDC is involved in maintaining/inducing tolerance. Depending on the agent used for ex vivo tolDC generation, cells acquire common features but prime T cells towards anergy, FOXP3+ Tregs, or Tr1 cells according to the levels of IL‐10 produced. Ex vivo‐induced tolDC were administered to patients to re‐establish/
Konstantina Morali +3 more
wiley +1 more source