Results 111 to 120 of about 913,373 (166)

Spatiotemporal expression of thyroid hormone transporter MCT8 and THRA mRNA in human cerebral organoids recapitulating first trimester cortex development

Scientific Reports
Thyroid hormones (TH) play critical roles during nervous system development and patients carrying coding variants of MCT8 (monocarboxylate transporter 8) or THRA (thyroid hormone receptor alpha) present a spectrum of neurological phenotypes resulting ...
Adina Sophie Graffunder, Audrey Amber Julie Bresser, Valeria Fernandez Vallone, Matthias Megges, Harald Stachelscheid, Peter Kühnen, Robert Opitz   +6 more
doaj   +1 more source

A bio-inspired neural environment to control neurons comprising radial glia, substrate chemistry and topography

, 2013
Achieving alignment of cells is key to the success of regenerative strategies of neural tissue. We report a high-throughput method to investigate neural cell response to surface chemistry overlaid orthogonally onto a gradient of gradually changing groove
Roach, Paul, Alexander, Morgan R., Parker, Terrance, Gadegaard, Nikolaj   +3 more
core   +1 more source

Coevolution of radial glial cells and the cerebral cortex

, 2015
Radial glia cells play fundamental roles in the development of the cerebral cortex, acting both as the primary stem and progenitor cells, as well as the guides for neuronal migration and lamination.
Camino De Juan Romero, Víctor Borrell, Borrell, Víctor, Juan Romero, Camino de   +3 more
core   +1 more source

Regional diversity of outer radial glia

Outer radial glia(oRG) cells are a key progenitor population in the developing cortex, believedto facilitate cortical expansion during midgestation. Several studies havehinted at the presence of oRG cells in the human ganglionic eminences (GEs),the ventral forebrain regions where inhibitory interneurons are produced, butthis has not been thoroughly ...
openaire   +1 more source

Author response: mTOR signaling regulates the morphology and migration of outer radial glia in developing human cortex

, 2020
Lakshmi Subramanian, Madeline G Andrews, Arnold R Kriegstein   +2 more
openaire   +1 more source

Müller glia: stem cells for generation and regeneration of retinal neurons in teleost fish [PDF]

, 2014
Adult zebrafish generate new neurons in the brain and retina throughout life. Growth-related neurogenesis allows a vigorous regenerative response to damage, and fish can regenerate retinal neurons, including photoreceptors, and restore functional vision ...
Raymond, Pamela, Lenkowski, Jenny
core  

Radial glia require PDGFD-PDGFRβ signalling in human but not mouse neocortex

, 2014
© 2014 Macmillan Publishers Limited. All rights reserved.Evolutionary expansion of the human neocortex underlies many of our unique mental abilities. This expansion has been attributed to the increased proliferative potential of radial glia (RG; neural ...
Oldham, Michael, Javaherian, A, Pollen, AA, Oldham, MC, Nowakowski, TJ, Kriegstein, Arnold, Lui, JH   +6 more
core  

Decision letter: mTOR signaling regulates the morphology and migration of outer radial glia in developing human cortex

, 2020
openaire   +1 more source

Sox8 and Sox9 regulate differentiation and nuclear positioning of retinal Müller glia. [PDF]

Development
Pannullo N, Datta D, Santiago CP, Tangeman JA, Jiang L, Duncan LH, Gohar T, Gimmen M, Blackshaw S.   +8 more
europepmc   +1 more source

An efficient and reproducible method to culture Bergmann and cortical radial glia using textured PMMA

Radial glia cells comprise the principal population of neural stem cells (NSC) during development. Attempts to develop reproducible radial glia and NSC culture methods have met with variable results, yielding non-adherent cultures or requiring the ...
Álvarez Pinto, Zaída, Mattotti, Marta, Engel López, Elisabeth, Sena, Elena, Alcantara, Soledad   +4 more
core