Results 71 to 80 of about 5,539,416 (160)

DNA replication fork speed acts as a pacer in cortical neurogenesis

Nature Communications
DNA replication fork speed, which controls the rate of genome duplication, has emerged as a key regulator of cellular plasticity. However, its role in neurogenesis remains unexplored.
Jianhong Wang, Yifan Kong, Xuezhuang Li, Dexi Chen, Kun Xiang, Yulian Tan, Lei Shi   +6 more
doaj   +1 more source

Dual‐Organelle Secretome Conjugation and Organ‐Uptake Tracking (DuO‐SCOUT) Enables Deep and Sensitive Mapping of the Secreted Proteins

Advanced Science, Volume 13, Issue 61, 3 November 2026.
A novel dual‐organelle proximity labeling platform, DuO‐SCOUT, decodes the complex landscape of systemic organ‐organ communication by capturing both classical and unconventional secretomes. Application in metabolic models maps the adipose‐to‐brain secretory relay, identifying selective extra‐hypothalamic sites for adipose‐derived factors and expanding ...
Fenglian Yang, Rui Qian, Jiaxing Song, Xingqi Meng, Jin Young Kim, Kwok On Lai, Li Wang, Liang Zhang   +7 more
wiley   +1 more source

Cxcr4 and Cxcl12 expression in radial glial cells of the brain of adult zebrafish.

, 2010
International audienceUnlike that of mammals, the brain of adult teleost fish exhibits an intense and widespread neurogenic activity as a result of the persistence of radial glial cells acting as neural progenitors throughout life.
Arianna Servili, Servili, Arianna, Colette Vaillant, Svetlana Mironov, Marie-Madeleine Gueguen, Mironov, Svetlana, Kah, Olivier, Isabelle Anglade, Nicolas Diotel, Elisabeth Pellegrini, Diotel, Nicolas, Pellegrini, Elisabeth, Olivier Kah, Anglade, Isabelle, Gueguen, Marie-Madeleine, Vaillant, Colette   +15 more
core   +1 more source

Red Fluorescent Labeling of Myelin by Membrane‐Targeted tdTomato in Transgenic Mouse Lines [PDF]

Glia
Transgenic mouse lines expressing membrane‐targeted tdTomato in myelin enable imaging of myelin in the red spectral range. Distinct expression patterns range from wide‐spread labeling to sparse single‐cell resolution, supporting diverse imaging applications.
Reinert A, Winkler U, Goebbels S, Komarek L, Möbius W, Zanker H, Schoknecht K, Bornschein G, Schmidt H, Fledrich R, Stassart R, Hirrlinger P, Nave K, Werner H, Saab A, Hirrlinger J.   +15 more
europepmc   +2 more sources

Curcumin in the Treatment of Various Diseases: Mechanism of Action, Bioavailability, Therapeutic Effects, and Current Clinical Trials

MedComm, Volume 7, Issue 11, November 2026.
Curcumin, a naturally occurring polyphenol, exhibits significant anti‐inflammatory and antioxidant capabilities. This review elucidates the specific molecular mechanisms by which curcumin exerts therapeutic effects on various diseases, including neurological disorders, cardiovascular diseases, cancers, inflammatory disorders, and autoimmune diseases ...
Lin Wang, Qifei Pan, Wenjuan Long, Xinyao Li, Jianqin Mao, Sitong Zhou, Zihui Wang, Xuelian Zou, Yuqing She, Mingqin Shi, Yang Zhou, Jiarong Du, Zhongyang Hu, Xiaoman Lv, Yishu Chen, Dongdong Qin   +15 more
wiley   +1 more source

How to Build a Spinal Cord: Exploring Radial Glial Proliferation and their Contribution to Embryonic Neurogenesis [PDF]

, 2015
During embryonic neural development, the concerted actions of neural stem cells (NSCs) populate and pattern the tissues that will give rise to the brain and spinal cord. This heterogeneous NSC population initially consists of neuroepithelial cells, which
Johnson, Kimberly A
core   +1 more source

Characterization of neurogenic niches and radial glial cells in the telencephalon of sharks: Comparative aspects and evolutionary implications [PDF]

, 2018
The telencephalon experiments many morphological and cytoarchitecture changes along evolution. For gaining understanding of the evolution of the telencephalon, we have analyzed the spatio-temporal pattern of several neurogenic and radial glial markers ...
Docampo Seara, Alberto
core  

Radial glial cell heterogeneity--the source of diverse progeny in the CNS.

, 2007
Here, we discuss the identity, heterogeneity and functions of radial glial cells mostly in the developing central nervous system (CNS). First, we define radial glial cells by morphological, cell biological and molecular criteria as true glial cells, akin
Götz, M., Pinto, L.
core   +1 more source

GFAP Expression of Radial Glial Cells of the Regenerating Spinal Cord of Axolotls

, 2020
Unlike humans, axolotls (Ambystoma mexicanum) possess the ability to completely regenerate their spinal cord following injury. It is theorized that the population of radial glial cells in the spinal cord act as the progenitors for the neurons populating ...
Fowler, Erin
core  

Axonal Versus Dendritic Outgrowth Is Differentially Affected by Radial Glia in Discrete Layers of the Retina

, 1998
Formation of neural cell polarity defined by oriented extension of axons and dendrites is a crucial event during the development of the nervous system.
Hubert Bauch, Burkhard Schlosshauer, Heike Stier   +2 more
core   +1 more source