Results 241 to 250 of about 121,702 (332)

Precision‐Guided Stealth Missiles in Biomedicine: Biological Carrier‐Mediated Nanomedicine Hitchhiking Strategy

open access: yesAdvanced Science, Volume 12, Issue 21, June 5, 2025.
Diagram illustrating the binding methods of NPs and biological barriers. The biological carrier‐mediated nanomedicine hitchhiking strategy (BCM‐NHS) utilizes two distinct techniques: the surface‐based “Backpack” method, which relies on ligand‐receptor binding, covalent conjugation, and non‐covalent binding, and the encapsulated “Trojan horse” approach,
Yuyan Zhou   +17 more
wiley   +1 more source

Advances in Cytosolic Delivery of Proteins: Approaches, Challenges, and Emerging Technologies

open access: yesChemistry &Biodiversity, Volume 22, Issue 6, June 2025.
Proteins regulate almost all biological processes, and overcoming the protein's natural membrane inpermeability will provide a unique opportunity for intracellular targeting of related therapeutic proteins. Chemical modification of proteins and different types of delivery vectors can mediate intracellular transport of proteins, providing new ideas for ...
Wenyan Zhang   +8 more
wiley   +1 more source

SEC‐SAXS/MC Ensemble Structural Studies of the Microtubule Binding Protein Cdt1 Show Monomeric, Folded‐Over Conformations

open access: yesCytoskeleton, Volume 82, Issue 6, Page 372-387, June 2025.
ABSTRACT Cdt1 is a mixed folded protein critical for DNA replication licensing and it also has a “moonlighting” role at the kinetochore via direct binding to microtubules and the Ndc80 complex. However, it is unknown how the structure and conformations of Cdt1 could allow it to participate in these multiple, unique sets of protein complexes.
Kyle P. Smith   +9 more
wiley   +1 more source

Time-resolved small-angle X-ray scattering system development for the biological macromolecules at SACLA: A pilot study. [PDF]

open access: yesBiophys Physicobiol
Shimizu N   +6 more
europepmc   +1 more source

Anti‐Inflammatory and Antioxidant Activities of Polyphenols From Loquat (Eriobotrya japonica Lindl.) Leaf Hair in Lipopolysaccharide‐Induced In Vitro and In Vivo Models

open access: yeseFood, Volume 6, Issue 3, June 2025.
This study identifies polyphenols in loquat leaf hair with potent antioxidant and anti‐inflammatory activities, demonstrating their efficacy in mitigating LPS‐induced oxidative stress and inflammation In Vitro and In Vivo via modulation of the Jak2–Stat3 and Nrf2–Keap1 pathways.
Can Hu   +10 more
wiley   +1 more source

Industrial Trans Fatty Acids Promote the Development of Food Allergy in a Mouse Model. [PDF]

open access: yesAllergy Asthma Immunol Res
Fu W   +10 more
europepmc   +1 more source

Home - About - Disclaimer - Privacy