Arginine mutation alters binding of a human monoclonal antibody to antigens linked to systemic lupus erythematosus and the antiphospholipid syndrome [PDF]
Objective: Previous studies have shown the importance of somatic mutations and arginine residues in the complementarity-determining regions (CDRs) of pathogenic anti-double-stranded DNA (anti-dsDNA) antibodies in human and murine lupus, and in studies of
Giles, I.+7 more
core +1 more source
Structural Differences of Ovalbumin and S-Ovalbumin Revealed by Denaturing Conditions
We found, by circular dichroism and Raman spectroscopy measurements, that the secondary structure of the native ovalbumin and of its heat-stable form, called S-ovalbumin, is a probe of the structural differences between the two proteins. Small angle X-ray scattering and circular dichroism measurements performed on the two proteins under denaturing ...
Paolinelli C+6 more
openaire +4 more sources
Some Differences Noted between the Properties of Ovalbumin and s-Ovalbumin in Native State [PDF]
To study the mechanism of the formation of the heat-stable form of ovalbumin (s-ovalbumin), comparisons were made about the properties of ovalbumin and s-ovalbumin in native state. Although gross structural difference could not be found, some minor differences were clearly noted in some cases such as the DEAE-cellulose chromatographic elution pattern ...
Ryo Nakamura+2 more
openaire +3 more sources
Conformational Changes Involved in the Switch from Ovalbumin to S-Ovalbumin
Abstract For the first time a comparative study on conformational differences between native oval buminand its heat-stable form, called S-ovalbumin. using small angle x-ray scattering, is reported. To detect a different pathway in the folding mechanism of the two proteins, scattering measurements have been performed on ovalbumin and S ...
Castellano AC+5 more
openaire +4 more sources
Performance evaluation of optical attocells configuration in an indoor visible light communication [PDF]
Visible light communication VLC is deemed as futuristic technology applied for both illumination and data communication due to the low-cost energy consumption, long life expectancy, huge bandwidth, and high security compared to radio frequency RF ...
Abdullah, Mohammad Faiz Liew+1 more
core +1 more source
The use of sulfated polysaccharides (fucoidans) as active pharmaceutical ingredients or adjuvants poses the challenge of obtaining structurally characterised and homogeneous samples or their oligomeric fractions maintaining high biological activity.
T. A. Kuznetsova+6 more
doaj +1 more source
Serpins : form, function and dysfunction [PDF]
The serpin superfamily of serine protease inhibitors is one of the most ubiquitous and successful classes of inhibitors in the living world. Their unique mechanism of suicide inhibition has led to much research and several important discoveries.
Cassar, Nicholas J., Hunter, Gary J.
core +1 more source
Lung inflammation by fungus, Bjerkandera adusta isolated from Asian sand dust (ASD) aerosol and enhancement of ovalbumin-induced lung eosinophilia by ASD and the fungus in mice. [PDF]
BackgroundBjerkandera adusta (B. adusta) is one of the most important etiological fungi associated with chronic cough. However, precise details of the inflammatory response to exposure are not well understood yet. B.
Arashidani, Keiichi+11 more
core +1 more source
Generalized Lévy walks and the role of chemokines in migration of effector CD8+ T cells. [PDF]
Chemokines have a central role in regulating processes essential to the immune function of T cells, such as their migration within lymphoid tissues and targeting of pathogens in sites of inflammation.
Banigan, Edward J+11 more
core +2 more sources
Ovalbumin is synthesized in mouse cells transformed with the natural chicken ovalbumin gene. [PDF]
The entire chicken ovalbumin gene, accompanied by genomic DNA sequences flanking both termini of the gene and three copies of the herpes simplex virus thymidine kinase gene, has been cloned in plasmid pBR322. This recombinant plasmid was linearized and used to transform thymidine kinase-deficient mouse cells.
Bert W. O'Malley+4 more
openaire +4 more sources