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An epigenetic hypothesis for ovarian cancer prevention by oral contraceptive pill use [PDF]

open access: yesClinical Epigenetics, 2023
Background Ovarian cancer is the second most common gynecological cancer type after uterine cancers. In 2020, according to worldwide statistics, there were more than 313,000 new cases of ovarian cancer.
Anna S. Avramenko, James M. Flanagan
doaj   +2 more sources

Resveratrol Targets a Variety of Oncogenic and Oncosuppressive Signaling for Ovarian Cancer Prevention and Treatment [PDF]

open access: yesAntioxidants, 2021
Ovarian cancer is a heterogeneous disease and is also the major cause of death among women from gynecologic malignancies. A combination of surgery and chemotherapy is the major therapy for ovarian cancer.
Xue-Ling Xu   +3 more
doaj   +2 more sources

Factors influencing decision-making on opportunistic salpingo-oophorectomy for ovarian cancer prevention in women with gastrointestinal cancers undergoing intra-abdominal surgery [PDF]

open access: yesGynecologic Oncology Reports
Objective: To assess the attitudes of women with non-gynecologic cancers undergoing intra-abdominal surgery toward opportunistic salpingo-oophorectomy (OSO) for ovarian cancer prevention, and to identify factors influencing their decision-making ...
Jaekyung Bae, Uisuk Kim, Sokbom Kang
doaj   +2 more sources

Ovarian Cancer in China:Trends in Incidence and Mortality,2005—2016 [PDF]

open access: yesZhongguo quanke yixue, 2022
BackgroundThe health impairment caused by ovarian cancer in female population has become a global focus. However, there is a lack of research on ovarian cancer incidence and mortality trends in Chinese female population.ObjectiveTo describe the trends of
HUANG Haitao, CHEN Shuyu, GENG Xu, WAN Xiao, JIA Ruiying, LIANG Dandan, CHEN Chaoran
doaj   +1 more source

ORGAVADS: establishment of tumor organoids from head and neck squamous cell carcinoma to assess their response to innovative therapies

open access: yesBMC Cancer, 2023
Background Radiotherapy is one of the cornerstones of the treatment of Head and Neck Squamous Cell Carcinomas (HNSCC). However, radioresistance is associated with a high risk of recurrence.
Marion Perréard   +26 more
doaj   +1 more source

The TRIPLEX study: use of patient-derived tumor organoids as an innovative tool for precision medicine in triple-negative breast cancer

open access: yesBMC Cancer, 2023
Background Triple negative breast cancers (TNBC) account for approximately 15% of all breast cancers and are associated with a shorter median survival mainly due to locally advanced tumor and high risk of metastasis. The current neoadjuvant treatment for
Jordane Divoux   +25 more
doaj   +1 more source

Comparative analysis of response to treatments and molecular features of tumor-derived organoids versus cell lines and PDX derived from the same ovarian clear cell carcinoma

open access: yesJournal of Experimental & Clinical Cancer Research, 2023
Background In the era of personalized medicine, the establishment of preclinical models of cancer that faithfully recapitulate original tumors is essential to potentially guide clinical decisions.
Lucie Thorel   +23 more
doaj   +1 more source

Primary Prevention of Ovarian Cancer

open access: yesZhongliu Fangzhi Yanjiu, 2023
Ovarian cancer is the most lethal malignancy of the female genital tract. Genetic predisposition, usage of hormone, relative disease and reproduction, and lifestyle factors are possible risk factors for ovarian cancer.
SHEN Li'na, ZANG Rongyu
doaj   +1 more source

Ovarian Cancer: From Precursor Lesion Identification to Population-Based Prevention Programs

open access: yesCurrent Oncology, 2023
Epithelial ovarian cancer (EOC) is a heterogeneous group of malignancies, including high-grade serous ovarian cancer (HGSC). HGSC is often diagnosed at advanced stages and is linked to TP53 variants.
Ramlogan Sowamber   +3 more
doaj   +1 more source

Predictors of cardiopulmonary fitness in cancer-affected and -unaffected women with a pathogenic germline variant in the genes BRCA1/2 (LIBRE-1)

open access: yesScientific Reports, 2022
Physical activity (PA) helps prevention and aftercare of sporadic breast cancer (BC), cardiopulmonary fitness (CPF) being an age-independent predictor of tumor-specific mortality.
A. Berling-Ernst   +14 more
doaj   +1 more source

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